Voltage-dependent anion channels mediated apoptosis in refractory epilepsy [PDF]
Open Medicine, 2020 The purpose of this study was to investigate the role of voltage-dependent anion channel (VDAC) in mitochondria-mediated apoptosis of neurons in refractory epilepsy. Western blot analyses were carried out to detect the changes in cytochrome C, caspase 9,
Zhao Yan +4 more
doaj +5 more sources
Microsporidia Interact with Host Cell Mitochondria via Voltage-Dependent Anion Channels Using Sporoplasm Surface Protein 1 [PDF]
mBio, 2019 Microsporidia are opportunistic intracellular pathogens that can infect a wide variety of hosts ranging from invertebrates to vertebrates. During invasion, the microsporidian polar tube pushes into the host cell, creating a protective microenvironment ...
Bing Han +8 more
doaj +4 more sources
Arabidopsis Voltage-Dependent Anion Channels (VDACs): Overlapping and Specific Functions in Mitochondria [PDF]
Cells, 2020 Voltage-dependent anion channels (VDACs) are essential components of the mitochondrial outer membrane. VDACs are involved in the exchange of numerous ions and molecules, from ATP to larger molecules such as tRNAs, and are supposed to adjust exchanges in ...
Mickaële Hemono +5 more
doaj +2 more sources
Arabidopsis Mitochondrial Voltage-Dependent Anion Channels Are Involved in Maintaining Reactive Oxygen Species Homeostasis, Oxidative and Salt Stress Tolerance in Yeast [PDF]
Frontiers in Plant Science, 2020 Voltage-dependent anion channels (VDACs) are conserved proteins of the mitochondria. We have functionally compared Arabidopsis VDACs using Saccharomyces cerevisiae Δpor1 and M3 yeast system.
Sibaji K. Sanyal +8 more
doaj +2 more sources
Voltage-Dependent Anion Channels in Male Reproductive Cells: Players in Healthy Fertility? [PDF]
BiomoleculesMale infertility affects nearly 50% of infertile couples, with various underlying causes, including endocrine disorders, testicular defects, and environmental factors. Spermatozoa rely on mitochondrial oxidative metabolism for motility and fertilization,
Stefano Conti Nibali +3 more
doaj +2 more sources
Tumor Biology, 2020 The exchange of metabolites between mitochondria and cytosol occurs through pores formed by voltage-dependent anion channel proteins. Voltage-dependent anion channels appear to be master regulators of mitochondrial bioenergetics and the intracellular ...
Paweł Jóźwiak +8 more
doaj +2 more sources
The Voltage-Dependent Anion Channels (VDAC) of Mycobacterium avium phagosome are associated with bacterial survival and lipid export in macrophages [PDF]
Scientific Reports, 2017 Mycobacterium avium subsp. hominissuis is associated with infection of immunocompromised individuals as well as patients with chronic lung disease. M. avium infects macrophages and actively interfere with the host killing machinery such as apoptosis and ...
Lia Danelishvili +4 more
doaj +2 more sources
Flexibility of the N-terminal mVDAC1 segment controls the channel's gating behavior. [PDF]
PLoS ONE, 2012 Since the solution of the molecular structures of members of the voltage dependent anion channels (VDACs), the N-terminal α-helix has been the main focus of attention, since its strategic location, in combination with its putative conformational ...
Barbara Mertins +7 more
doaj +5 more sources
Voltage‐dependent anion‐selective channel (VDAC) in the plasma membrane
FEBS Letters, 2010 Voltage‐dependent anion channels (VDACs) have originally been characterized as mitochondrial porins. Starting in the late 1980s, however, evidence began to accumulate that VDACs can also be expressed in plasma membranes. In this review, we briefly revisit the historical milestones in the discovery of plasma membrane‐bound VDAC, and we critically ...
Vito De Pinto +2 more
exaly +3 more sources
VDAC1 (voltage-dependent anion channel 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on VDAC1 (voltage-dependent anion channel 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Shoshan-Barmatz, V, Mizrachi, D
openaire +2 more sources