Results 161 to 170 of about 2,245,116 (239)

A physiologically-relevant intermediate state structure of a voltage-gated potassium channel. [PDF]

Nat Commun
Kyriakis E, Sastre D, Eldstrom J, Roscioni A, Russo S, Ataei F, Dou Y, Chan M, Molinarolo S, Maragliano L, Van Petegem F, Fedida D.   +11 more
europepmc   +1 more source

Ion Channel Modeling beyond State of the Art: A Comparison with a System Theory-Based Model of the Shaker-Related Voltage-Gated Potassium Channel Kv1.1. [PDF]

Cells, 2022
Langthaler S, Lozanović Šajić J, Rienmüller T, Weinberg SH, Baumgartner C.   +4 more
europepmc   +1 more source

Fire‐Safe Polymeric Insulation Foams for Energy‐Efficient and Low‐Carbon Buildings

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review systematically summarizes recent advances in fire‐safe polymeric insulation foams, emphasizing the balance among flame retardancy, thermal insulation, mechanical reliability, and long‐term durability. By linking material‐level thermophysical properties with building cooling‐energy demand and operational carbon emissions, it establishes a ...
Qinhe Guo, Jiayi Pan, Dehui Jia, Min Chen, Danni Pan, Yao Yuan, Ying Pan, Yan Zhang, Lulu Xu, Kate Nguyen, Wei Wang   +10 more
wiley   +1 more source

One model to rule them all: Unification of voltage-gated potassium channel models via deep non-linear mixed effects modelling. [PDF]

PLoS Comput Biol
Linkevicius D, Chadwick A, Stefan MI, Sterratt DC.   +3 more
europepmc   +1 more source

Cenobamate use in super‐refractory status epilepticus: A report of three cases

Epileptic Disorders, EarlyView.
Abstract Objectives Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...
Marina Romozzi, Juan Luis Alcala‐Zermeno, Antonio Funcis, Federico Tosto, Marta Piccioli, Luigi Francesco Iannone, Riccardo Maviglia, Masahito Katsuki, Yasuhiko Matsumori, Paolo Calabresi, Raffaele Iorio, Catello Vollono   +11 more
wiley   +1 more source

Protective function of the voltage-gated potassium channel Kv11.3 in a mouse model of cardiac ischemia/reperfusion injury. [PDF]

PLoS One
Sasaki H, Otake K, Takeda K, Tesaki K, Takahashi E, Yasuda J, Matsuda S, Kawasaki A, Watanabe M, Otani K, Okada M, Sekijima M, Yamawaki H, Sasaki N.   +13 more
europepmc   +1 more source

Electroclinical phenotypes—genetic characterization of developmental and epileptic encephalopathies in a cohort study

Epileptic Disorders, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by refractory seizures and frequently recurring epileptic activity with neurodevelopmental delay or regression that usually begin in early life. We aimed to define the relationship between electroclinical features and etiology, as well as the genotype–phenotype ...
Burcu Yaman, Fulya Kurekci, Sinan Akbas, Ceyda Oney, Mehmet Akif Kilic, Hulya Maras Genc, Ayca Dilruba Aslanger, Edibe Pembegul Yildiz   +7 more
wiley   +1 more source

Association of Voltage-Gated Potassium Channel Polymorphisms with the Risk and Prognosis of Epilepsy in the Saudi Population: A Case-Control Study. [PDF]

Medicina (Kaunas)
Alghamdi MA, Al-Eitan LN, Otaif MY, Rababa'h DM, Alasmar MK, Al-Garni AM, Saleh RAM, Abdel Ghaffar NF.   +7 more
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Complex partial seizures with orofacial involvement in 35 cats: MRI changes, cerebrospinal fluid analysis, voltage-gated potassium channel antibodies and survival. [PDF]

J Feline Med Surg
Flegel T, Matiasek K, Füsser M, Becker LF, Böttcher IC, Dietzel J, Gutmann S, Kalliwoda T, Loderstedt S, Tästensen C, Weiß V, Schulte LP, König JE.   +12 more
europepmc   +1 more source