Results 111 to 120 of about 2,526,088 (292)

Kinetic model based on molecular mechanism for action potential [PDF]

, 2011
The Hodgkin-Huxley model for action potentials has been widely used but was not built on a microscopic description of the neuronal membrane. Through molecular dynamics simulations, the molecular mechanism of the channel currents is becoming clear ...
Lizhong Xu
core  

Advanced Manufacturing of Composite‐Based Systems for Energy Applications

Advanced Materials Technologies, EarlyView.
Advanced manufacturing enables the integration of polymers, ceramics, metal oxides, and composites into architected microstructures with tailored transport pathways. By coupling material selection, manufacturing strategy, and structural design, multifunctional energy systems can simultaneously improve electrochemical performance, thermal management ...
Sri Vaishnavi Thummalapalli, Dhanush Patil, Libin Yang, M. Taylor Sobczak, Anshul Kulkarni, Xiao Sun, Arunachalam Ramanathan, Tiantian Li, Ramaraja P. Ramasamy, Jason J. Locklin, Yanyu Chen, Xianqiao Wang, Arunachala Mada Kannan, Kenan Song   +13 more
wiley   +1 more source

3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends

Advanced Robotics Research, EarlyView.
Collectively, this review systematically examines 3D‐printed soft robotics, encompassing material selections, function integration, and manufacturing methodologies. Meanwhile, fabrication strategies are analyzed in order of increasing complexity, highlighting persistent challenges with proposed solutions.
Changjiang Liu, Bin Cui, Xumin Huang, Xiaoyu (Rayne) Zheng, T. Thang Vo‐Doan, Ruirui Qiao   +5 more
wiley   +1 more source

The Role of Na1.9 Channel in the Development of Neuropathic Orofacial Pain Associated with Trigeminal Neuralgia

Molecular Pain, 2015
Background Trigeminal neuralgia is accompanied by severe mechanical, thermal and chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion (TG).
Ana Paula Lulz, Olga Kopach, Sonia Santana-Varela, John N. Wood   +3 more
doaj   +1 more source

Molecular and functional characterization of voltage-gated sodium channels in human sperm

Reproductive Biology and Endocrinology, 2009
Background We have investigated the expression of voltage-gated sodium channels in human spermatozoa and characterized their role in sperm motility. Methods Freshly ejaculated semen was collected from thirty normozoospermic human donors, with each donor ...
Cejudo-Román Antonio, Gallardo-Castro Manuel, Fernández-Sánchez Manuel, Ravina Cristina G, Pinto Francisco M, Candenas Luz   +5 more
doaj   +1 more source

Investigations on subunit-specific assembly and structure-function studies of the voltage sensor in KCNQ potassium channels [PDF]

, 2007
A detailed understanding of how potassium channels function is crucial e. g. for the development of drugs, which could lead to novel therapeutic concepts for diseases ranging from diabetes to cardiac abnormalities.
Athanasiadu, Despina, Athanasiadu, D.
core  

An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids [PDF]

, 2015
We describe the identification in aphids of a unique heterodimeric voltage-gated sodium channel which has an atypical ion selectivity filter and, unusually for insect channels, is highly insensitive to tetrodotoxin.
T. G. E. Davies (7694750), Joanna S. Amey, O'Reilly, Andrias O., Mellor, I. R., Burton, Mark J., M. S. Williamson (7694747), Martin S. Williamson, Duce, I. R., Mellor, I.R., B.A. Wallace, Andrias O. O'Reilly, O'Reilly, A. O., Mark J. Burton, Burton, M. J., Field, L.M., A. O. O'Reilly (7694732), Amey, Joanna S., Puinean, A. M., Davies, T.G. Emyr, T.G. Emyr Davies, A. M. Puinean (7694735), O’Reilly, Andrias O., Williamson, Martin S., Amey, J.S., Duce, Ian R., Williamson, M.S., I. R. Mellor (7694738), Duce, I.R., Field, Linda M., Linda M. Field, Mark J. Burton (7691339), Field, L. M., Alin M. Puinean, Ian R. Duce, Amey, J. S., Wallace, B.A., Ian R. Mellor, J. S. Amey (7694729), Davies, T. G. E., Williamson, M. S., B. A. Wallace (148558), I. R. Duce (7694741), Wallace, Bonnie A., Puinean, Alin M., Mellor, Ian R., L. M. Field (7694744), Wallace, B. A., Davies, T.G.E., Burton, M.J., Puinean, A.M.   +49 more
core   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Effects of acidosis on neuronal voltage-gated sodium channels: Nav1.1 and Nav1.3

Channels, 2018
Voltage-gated sodium channels are key contributors to membrane excitability. These channels are expressed in a tissue-specific manner. Mutations and modulation of these channels underlie various physiological and pathophysiological manifestations.
Mohammad-Reza Ghovanloo, Colin H. Peters, Peter C. Ruben   +2 more
doaj   +1 more source