Results 81 to 90 of about 107,111 (187)
Ciguatoxins: Cyclic Polyether Modulators of Voltage-gated Iion Channel Function
Marine Drugs, 2006 Ciguatoxins are cyclic polyether toxins, derived from marine dinoflagellates, which are responsible for the symptoms of ciguatera poisoning. Ingestion of tropical and subtropical fin fish contaminated by ciguatoxins results in an illness characterised by
Richard J. Lewis, Graham M. Nicholson
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Optimization of the leak conductance in the squid giant axon
, 2010 We report on a theoretical study showing that the leak conductance density, $\GL$, in the squid giant axon appears to be optimal for the action potential firing frequency.
A. L. Hodgkin +7 more
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Ion channels: structural basis for function and disease. [PDF]
, 1996 Ion channels are ubiquitous proteins that mediate nervous and muscular function, rapid transmembrane signaling events, and ionic and fluid balance. The cloning of genes encoding ion channels has led to major strides in understanding the mechanistic basis
Goldstein, SA
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Molecular and functional characterization of voltage-gated sodium channels in human sperm
Reproductive Biology and Endocrinology, 2009 Background We have investigated the expression of voltage-gated sodium channels in human spermatozoa and characterized their role in sperm motility. Methods Freshly ejaculated semen was collected from thirty normozoospermic human donors, with each donor ...
Cejudo-Román Antonio +5 more
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Neural Regeneration ResearchVoltage-gated sodium channels are essential ionic-conductance pathways in the nervous system, which play an irreplaceable role in modulating neuronal excitability and signal transduction.
Ni Li +5 more
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Frontiers in Cellular Neuroscience, 2017 Neurons are highly polarized cells with apparent functional and morphological differences between dendrites and axon. A critical determinant for the molecular and functional identity of axonal and dendritic segments is the restricted expression of ...
Jeffrey Lopez-Rojas +4 more
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α-Nemertides, a novel family of marine peptide neurotoxins from ribbon worms [PDF]
, 2017 Ribbon worms (nemerteans) are marine predators, which capture their prey using a proboscis containing a mixture of toxins which brings on rapid paralysis.
Tytgat, J.
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, 2009 We investigate the regularity of spontaneous spiking activity on Newman-Watts small-world networks consisting of biophysically realistic Hodgkin-Huxley neurons with a tunable intensity of intrinsic noise and fraction of blocked voltage-gated sodium and ...
Ozer, Mahmut +2 more
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Voltage-gated sodium channels assemble and gate as dimers
Nature Communications, 2017 Voltage-gated sodium channels are expressed in excitable tissues and mutations have been linked to cardiac arrhythmias and channelopathies. Here the authors show that the sodium channel α-subunits interact to form a dimer and gate as dimer and that this ...
Jérôme Clatot +9 more
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Detecting and Estimating Signals in Noisy Cable Structures, I: Neuronal Noise Sources [PDF]
, 1999 In recent theoretical approaches addressing the problem of neural coding, tools from statistical estimation and information theory have been applied to quantify the ability of neurons to transmit information through their spike outputs. These techniques,
Koch, Christof, Manwani, Amit
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