Results 41 to 50 of about 219,337 (367)
von Willebrand Disease: The diagnosis and management of this bleeding disorder
Medical Journal of Babylon, 2020 von Willebrand disease (vWD) is one of the most common bleeding disorders, first described by Erik von Willebrand in the Aland Islands. It occurs as a result of decreased or abnormal von Willebrand factor (vWF), a factor that is needed in the process of ...
Basim A. Abd, Nawrass J Al-Salihi
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Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]
, 2009 The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Bõze, Tamás +9 more
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Clinical Pediatric Hematology-Oncology, 2021 von Willebrand disease (VWD) is the most common hereditary bleeding disorder. The treatment of VWD consists mainly of desmopressin and plasma-derived von Willebrand factor (pd-VWF) concentrate.
Seoin Kim, Young Shil Park
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Von Willebrand factor, angiodysplasia and angiogenesis [PDF]
, 2013 The large multimeric glycoprotein Von Willebrand factor (VWF) is best known for its role in haemostasis; however in recent years other functions of VWF have been identified, indicating that this protein is involved in multiple vascular processes.
Laffan, MA, Randi, AM, Starke, RD
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Journal of Thrombosis and Haemostasis, 2018 Essentials Elevated procoagulant levels are associated with an increased risk of venous thrombosis (VT). The dependency on concurrent increased factor levels and VT was analyzed in a large study.
I. M. Rietveld +6 more
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Haematologica, 2017 Factor VIII C-domains are believed to have specific functions in cofactor activity and in interactions with von Willebrand factor. We have previously shown that factor VIII is co-targeted with von Willebrand factor to the Weibel-Palade bodies in blood ...
Eduard H.T.M. Ebberink +7 more
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Desmopressin in moderate hemophilia a patients: A treatment worth considering [PDF]
, 2018 Desmopressin increases endogenous factor VIII levels in hemophilia A. Large inter-individual variation in the response to desmopressin is observed.
Beckers, E. +12 more
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The role of von Willebrand factor in determining the risk of ischemic stroke in Hawler city: a case-control study [PDF]
Zanco Journal of Medical Sciences, 2018 Background and objective: Ischemic stroke is classically characterized as a neurological deficit attributed to an acute focal injury of the central nervous system by a vascular cause, it occurs as a result of obstruction by a blood clot (thrombus) or ...
Sazgar Anwar Hameed, Salar Adnan Ahmed
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Flow-induced elongation of von Willebrand factor precedes tension-dependent activation
Nature Communications, 2017 Von Willebrand factor, an ultralarge concatemeric blood protein, must bind to platelet GPIbα during bleeding to mediate hemostasis, but not in the normal circulation to avoid thrombosis.
Hongxia Fu +5 more
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ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis [PDF]
, 2005 Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and progression of arthritis.
Jones, GC, Riley, GP
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