Results 41 to 50 of about 109,978 (227)

Successful Aortic Aneurysm Repair in a Woman with Severe von Willebrand (Type 3) Disease

Case Reports in Hematology, 2015
von Willebrand disease type 3 (VWD3) is a rare but the most severe form of von Willebrand disease; it is due to almost complete lack of von Willebrand factor activity (VWF:RCo).
Victoria Campbell, Kevin Marriott, Rex Stanbridge, Abdul Shlebak   +3 more
doaj   +1 more source

Ibrutinib effect in acquired von Willebrand syndrome secondary to Waldenström macroglobulinemia

Therapeutic Advances in Hematology, 2021
The pathological increase of clonal IgM in Waldenström macroglobulinemia can be associated with acquired von Willebrand syndrome and can be a major risk of bleeding symptoms in this subgroup of patients with Waldenström macroglobulinemia.
María Poza, Rodrigo Íñiguez, Irene Zamanillo, Sara Redondo, Rafael Alonso, Joaquín Martínez-López, Ana Jiménez-Ubieto   +6 more
doaj   +1 more source

Acquired Von Willebrand Factor Deficiency at Patient-Prosthesis Mismatch after AVR Procedure—A Narrative Review

Medicina, 2023
Acquired von Willebrand factor deficiency has been described in patients with aortic valve stenosis due to high shear forces developed during passage through the narrowed valve orifice, which determines structural changes in this molecule.
Andrei Emanuel Grigorescu, Andrei Anghel, Darius Gheorghe Buriman, Horea Feier   +3 more
doaj   +1 more source

Nitric Oxide and Von Willebrand Factor Levels as Markers of Endothelial Dysfunction in Liver Cirrhosis [PDF]

, 2002
Introduction: A number of investigators have shown that endothelial dysfunction in liver cirrhosis can be indicated by increased levels of nitric oxide (NO) and von Willebrand factor (vWF). The cause of this increase is still unclear. It is believe to be
Ginting, S. (Suara), Nababan, A. (Abiran), Sembiring, J. (Juwita), Tarigan, P. (Pengarapen), Zain, L. H. (Lukman)   +4 more
core  

Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ibα

Haematologica, 2013
Initial platelet arrest at the exposed arterial vessel wall is mediated through glycoprotein Ibα binding to the A1 domain of von Willebrand factor. This interaction occurs at sites of elevated shear force, and strengthens upon increasing hydrodynamic ...
Eelo Gitz, Charlotte D. Koopman, Alèkos Giannas, Cornelis A Koekman, Dave J. van den Heuvel, Hans Deckmyn, Jan-Willem N. Akkerman, Hans C. Gerritsen, Rolf T. Urbanus   +8 more
doaj   +1 more source

Desmopressin testing in von Willebrand disease: Lowering the burden

Research and Practice in Thrombosis and Haemostasis, 2022
Background Individuals with von Willebrand disease (VWD) require desmopressin testing because of interindividual response differences. However, testing is burdensome, while not all patients may need extensive testing. Objectives To provide von Willebrand
Jessica M. Heijdra, Ferdows Atiq, Wala Al Arashi, Quincy Kieboom, Esmee Wuijster, Karina Meijer, Marieke J. H. A. Kruip, Frank W. G. Leebeek, Marjon H. Cnossen, in collaboration with the OPTI‐CLOT Study Group   +9 more
doaj   +1 more source

Az érfal trombogenitása és annak szabályozása = Vessel wall thrombogenicity and its regulation [PDF]

, 2008
Fiziológiás hemosztázis ill. artériás trombózis keletkezésekor a trombociták a gyorsan áramló vérből von Willebrand faktoron keresztül tapadnak ki az érfalban lévő kollagénhez. Az érfal mátrix komponenseit vizsgálva megállapítottuk, hogy a media rétegből
Gombás, Judit, Komorowicz, Erzsébet, Váradi, Balázs   +2 more
core  

Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner

Renal Failure, 2019
Background: Cadmium (Cd) is an environmental pollutant that leads to nephrotoxicity. However, the mechanisms of Cd-induced glomerular injury have not been fully clarified. Von Willebrand factor (vWF) and occludin are important endothelial cell markers in
Zongguo Sun, Qi Xie, Jie Pan, Na Niu
doaj   +1 more source

Some aspects of pathogenesis of erosive-ulcerous gastric lesions in liver cirrhosis patients [PDF]

, 2014
Von Willebrand factor, tumor necrosis factor-α levels and portal bloodstream were examined in 47 patients with liver cirrhosis and 8 apparently healthy persons.
Fediv, O.I., Palibroda, N.M.
core  

Migraine and vascular disease biomarkers: A population-based case-control study. [PDF]

, 2018
Background The underpinnings of the migraine-stroke association remain uncertain, but endothelial activation is a potential mechanism. We evaluated the association of migraine and vascular disease biomarkers in a community-based population.
Ferrari, Michel D., Herial, Nabeel, Khubchandani, Jagdish, Koppen, Hille, Kruit, Mark C., Launer, Lenore J., Palm-Meinders, Inge H., Terwindt, Gisela M., Tietjen, Gretchen E., van Buchem, Mark A.   +9 more
core   +2 more sources