Results 71 to 80 of about 20,520 (215)

Molecular characterization of the VP1, VP2, VP4, VP6, NSP1 and NSP2 genes of bovine group B rotaviruses: identification of a novel VP4 genotype [PDF]

Archives of Virology, 2009
Studies on bovine group B rotaviruses (GBRs) are limited. To date, only the VP6 gene of a single bovine GBR strain and the VP7 and NSP5 genes of a few bovine GBR strains have been sequenced and analyzed. In the present study, using a single-primer amplification method, we have determined the full-length nucleotide sequences of the VP1, VP2, VP4, VP6 ...
Ghosh, S, Kobayashi, N, Nagashima, S, Chawla-Sarkar, M, Krishnan, T, Ganesh, B, Naik, TN   +6 more
openaire   +3 more sources

Colocalization of NS80 and GFP-VP4 in inclusion structures. A

, 2013
. Fluorescence microscope or IF analysis of Vero cells transfected with plasmid pEGFP-C1-VP4 (row1) or cotransfected with pEGFP-C1 and pCI-neo-NS80 (row2). B.
Huan Liu (281351), Hong Guo (142424), Li-Ming Yan (281350), Qin Fang (281352), Ling Shao (281349)   +4 more
core   +1 more source

Borderline Resectable Classification Identifies Candidates for Conversion Therapy in Unresectable Hepatocellular Carcinoma Treated With Atezolizumab and Bevacizumab

Hepatology Research, Volume 56, Issue 5, Page 830-839, May 2026.
ABSTRACT Background Conversion therapy, which seeks to achieve curative treatment following systemic therapy, is increasingly acknowledged in the management of unresectable hepatocellular carcinoma (HCC). However, validated criteria for predicting eligibility for conversion remain unclear. We investigated the utility of the recently proposed borderline
Yasuto Takeuchi, Masahiko Sue, Nozomi Miyake, Takuya Adachi, Hideki Onishi, Miwa Kawanaka, Akinobu Takaki, Kazuhiro Nouso, Kazuya Kariyama, Shinichiro Nakamura, Emi Tanaka, Toshifumi Tada, Tetsuya Yasunaka, Kenji Kuwaki, Junichi Toshimori, Shota Iwado, Akio Moriya, Hiroaki Hagihara, Hiroyuki Takabatake, Masahiro Sakata, Motoyuki Otsuka   +20 more
wiley   +1 more source

Three‐dimensional structure of the rotavirus haemagglutinin VP4 by cryo‐electron microscopy and difference map analysis. [PDF]

, 1994
The three-dimensional structure of the rotavirus spike haemagglutinin viral protein 4 (VP4) has been determined to a resolution of 26 A by cryo-electron microscopy and difference analysis of intact virions and smooth (spikeless) particles.
Bellamy, AR, Baker, TS, Yeager, M, Berriman, JA   +3 more
core   +1 more source

Age‐Related Asymptomatic Rhinovirus Infections Contribute to the Sustained Prevalence in Adults and Are Not Mitigated by Nonpharmaceutical Interventions

Influenza and Other Respiratory Viruses, Volume 20, Issue 5, May 2026.
ABSTRACT Background Rhinovirus (RV) is a common respiratory virus, but asymptomatic RV infections in adults still require further investigation. Nonpharmaceutical interventions (NPIs) for COVID‐19 markedly reduced other respiratory viruses, yet RV circulation appeared to persist.
Dong Wei, Wei Tan, Chenyue Tang, Weihui Ma, Yulong Li, Zhitao Yang, Xinxin Zhang   +6 more
wiley   +1 more source

VP4 fusion-loop mutant and VP7 disulfide-linked trimer.

, 2014
A. Effects of mutations on uncoating. Particles recoated with VP4 fusion-loop mutant (top panel) and VP7 disulfide-linker trimer (bottom panel) added to BSC-1 cells and imaged at 2 min and 45 min. All particles in the field at 45 sec retain VP7.
Aliaa H. Abdelhakim (628663), Tomas Kirchhausen (241303), Xiaofeng Fu (130116), Daniela Nicastro (130119), Eric N. Salgado (628664), Mithun Pasham (628665), Stephen C. Harrison (173989)   +6 more
core   +1 more source

Grass carp reovirus VP4 manipulates TOLLIP to degrade STING for inhibition of IFN production

Journal of Virology
Although fish possess an effective interferon (IFN) system to defend against viral infection, grass carp reovirus (GCRV) still causes epidemic hemorrhagic disease and tremendous economic loss in grass carp.
Yang-Yang Wang, Xue-Li Wang, Zhuo-Cong Li, Can Zhang, Xiao Xu, Bao-Jie Cui, Meng-Ze Tian, Chu-Jing Zhou, Na Xu, Yue Wu, Xiao-Li Yang, Dan-Dan Chen, Long-Feng Lu, Shun Li   +13 more
doaj   +1 more source

Significant response to atezolizumab plus bevacizumab treatment in unresectable hepatocellular carcinoma with major portal vein tumor thrombus: a case report

BMC Gastroenterology, 2021
Background Hepatocellular carcinoma (HCC) with major portal vein tumor thrombus (Vp4 PVTT) is an extremely advanced tumor with limited treatment options.
Shohei Komatsu, Yoshimi Fujishima, Masahiro Kido, Kaori Kuramitsu, Tadahiro Goto, Hiroaki Yanagimoto, Hirochika Toyama, Takumi Fukumoto   +7 more
doaj   +1 more source

Systemic Therapy for Advanced Hepatocellular Carcinoma in 2026: Current Standard‐of‐Care and Emerging Therapeutic Strategies

Journal of Gastroenterology and Hepatology, Volume 41, Issue 5, Page 1436-1445, May 2026.
ABSTRACT Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, accounting for up to 80% of all cases. Most patients present at an advanced stage and are unsuitable for curative treatments. In the past 5 years, immunotherapy combination has superseded tyrosine kinase inhibitors (TKI) as the standard first‐line therapy for ...
Landon L. Chan, Kallista O. K. Chan, Stephen L. Chan   +2 more
wiley   +1 more source

A novel type of VP4 carried by a porcine rotavirus strain

Virology, 2003
The gene encoding the VP8* trypsin-cleavage product of the VP4 protein of porcine rotavirus strain A34 was sequenced, and the predicted amino acid (aa) sequence was compared to the homologous region of all known P genotypes. The aa sequence of the VP8* of strain A34 shared low identity, ranging from 39% (bovine strain B223, P8[11]) to 76% (human strain
Liprandi, Ferdinando, Gerder, Marlene, Bastidas, Zoleida, López, José A., Pujol, Flor H., Ludert, Juan E., Joelsson, Daniel B., Ciarlet, Max   +7 more
openaire   +2 more sources