Results 81 to 90 of about 20,520 (215)

SV40 Late Protein VP4 Forms Toroidal Pores To Disrupt Membranes for Viral Release

open access: yes, 2016
Nonenveloped viruses are generally released from the cell by the timely lysis of host cell membranes. SV40 has been used as a model virus for the study of the lytic nonenveloped virus life cycle. The expression of SV40 VP4 at later times during infection
Fabian B. Romano (215326)   +4 more
core   +1 more source

Molecular Classification of Enteroviruses Not Identified by Neutralization Tests

open access: yesEmerging Infectious Diseases, 2002
We isolated six viruses from patients diagnosed with aseptic meningitis or hand, foot, and mouth disease. The cytopathic effect of these viruses on cultured cells was like that of enteroviruses.
Hideyuki Kubo   +2 more
doaj   +1 more source

Durvalumab–Tremelimumab in Advanced Hepatocellular Carcinoma: Real‐World Data From the LOR‐HCC (Lombardy Real‐World HCC Group)

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aim Dual immune checkpoint blockade with tremelimumab plus durvalumab (STRIDE) is an established first‐line therapy for unresectable hepatocellular carcinoma (uHCC); however, real‐world evidence on its safety, toxicity kinetics and liver function dynamics remains limited.
Andrea Casadei‐Gardini   +27 more
wiley   +1 more source

Vector‐borne diseases‐knowledge maps

open access: yesEFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This scientific report provides a structured overview of the main characteristics of 25 selected vector‐borne diseases (VBDs) of potential relevance for the EU, including 12 diseases listed under the Animal Health Law (AHL) and 13 non‐listed diseases.
European Food Safety Authority (EFSA)   +7 more
wiley   +1 more source

Independent segregation of the VP4 and the VP7 genes in bovine rotaviruses as confirmed by VP4 sequence analysis of G8 and G10 bovine rotavirus strains

open access: yesJournal of General Virology, 1993
We determined the complete nucleotide sequences of the VP4 genes of five bovine rotavirus strains (A5, 61A, A44, B223 and KK3). The deduced VP4 amino acid sequence of strain A5 with G8 serotype specificity is 91.1% identical to that of strain NCDV of the serotype G6, and strain 61A with G10 serotype specificity has a VP4 amino acid sequence (95.2 ...
K, Taniguchi, T, Urasawa, S, Urasawa
openaire   +2 more sources

The VP5 Domain of VP4 Can Mediate Attachment of Rotaviruses to Cells [PDF]

open access: yesJournal of Virology, 2000
ABSTRACT Some animal rotaviruses require the presence of sialic acid (SA) on the cell surface to infect the cell. We have isolated variants of rhesus rotavirus (RRV) whose infectivity no longer depends on SA. Both the SA-dependent and -independent interactions of these viruses with the cell are mediated by the virus spike protein
S, Zárate   +5 more
openaire   +2 more sources

Distinct Host Gene Expression Patterns Induced by Covert Deformed Wing Virus Infections in Honeybees (Apis mellifera)

open access: yesArchives of Insect Biochemistry and Physiology, Volume 121, Issue 4, April 2026.
A transcriptome study was established in Ordu, Türkiye using genetically related A. mellifera anatoliaca colonies founded by super‐sister queens. Nurse bees were collected and high‐quality RNA was sequenced on an Illumina NovaSeq 6000 platform, and analyzed on the Sabancı University HPC cluster (1).
Ali Sinan Kara   +8 more
wiley   +1 more source

Foot-and-mouth disease virus VP4: roles in membrane permeability and capsid breathing [PDF]

open access: yes, 2018
Foot-and-mouth disease virus (FMDV) is an economically-important picornavirus that infects cloven hooved animals. Entry is a vital step in the virus lifecycle and results in conformational changes in the capsid, including release of the capsid protein ...
Swanson, Jessica Jane
core  

Pigeon rotavirus VP4, VP7 and phylogeny.

open access: yes, 2013
A. Pair-wise sliding window of % nucleotide similarity of pigeon rotavirus VP4 and VP7 genes aligned with the related rotavirus species. B. Phylogenetic analyses of VP4 and VP7 proteins of pigeon rotavirus and representatives of all rotavirus species ...
Eric Delwart (123223)   +9 more
core   +1 more source

Efficacy and Safety of Intensity‐Modulated Radiotherapy Combined With Regorafenib With or Without Immune Checkpoint Inhibitors as Second‐Line Treatment for Advanced Hepatocellular Carcinoma: A Real‐World Cohort Study From a Single Center

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Purpose This study aimed to assess the efficacy and safety of intensity‐modulated radiotherapy (IMRT) combined with regorafenib with or without immune checkpoint inhibitors (ICIs) as a second‐ or later‐line treatment for advanced hepatocellular carcinoma (HCC).
Lingxia Xin   +22 more
wiley   +1 more source

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