Results 31 to 40 of about 2,910 (199)

Lactobacillus acidophilus Expressing Murine Rotavirus VP8 and Mucosal Adjuvants Induce Virus-Specific Immune Responses

, 2023
Rotavirus diarrhea-associated illness remains a major cause of global death in children under five, attributable in part to discrepancies in vaccine performance between high- and low-middle-income countries.
Darby Gilfillan, Meichen Pan, Gregg A. Dean, Harry B. Greenberg, Allison C. Vilander, Bridget E. Fox, Yong Jun Goh, Sarah O’Flaherty, Rodolphe Barrangou, Ningguo Feng, Callie Lang, Zaid Abdo   +11 more
core   +1 more source

Subcellular redistribution and sequential recruitment of macromolecular components during SGIV assembly

Protein & Cell, 2016
Virus infection consists of entry, synthesis of macromolecular components, virus assembly and release. Understanding of the mechanisms underlying each event is necessary for the intervention of virus infection in human healthcare and agriculture. Here we
Yongming Yuan, Yunhan Hong
doaj   +1 more source

Transmission of potato spindle tuber viroid between Phytophthora infestans and host plants

Вавиловский журнал генетики и селекции, 2022
Potato spindle tuber viroid (PSTVd) is a naked, circular, single-stranded RNA (356–363 nucleotides in length) which lacks any protein-coding sequences.
O. S. Afanasenko, A. V. Khiutti, N. V. Mironenko, N. M. Lashina   +3 more
doaj   +1 more source

Phage VP882 is more virulent in QS-competent V. parahaemolyticus than in QS-deficient V. parahaemolyticus.

, 2023
(A) Quantitation of viral particles collected from the indicated 882 strains carrying arabinose-inducible vqmAPhage grown in medium lacking (black bars) or containing 0.02% arabinose (white bars). Relative viral load is the amount of phage VP882-specific
Olivia P. Duddy (9954319), Justin E. Silpe (1317783), Bonnie L. Bassler (41611), Chenyi Fei (10515970)   +3 more
core   +1 more source

Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens.

PLoS Pathogens, 2020
Initial cell attachment of rotavirus (RV) to specific cell surface glycan receptors, which is the essential first step in RV infection, is mediated by the VP8* domain of the spike protein VP4.
Shenyuan Xu, Luay U Ahmed, Michael Robert Stuckert, Kristen Rose McGinnis, Yang Liu, Ming Tan, Pengwei Huang, Weiming Zhong, Dandan Zhao, Xi Jiang, Michael A Kennedy   +10 more
doaj   +1 more source

Effects of Rotavirus NSP4 on the Immune Response and Protection of Rotavirus-Norovirus Recombinant Subunit Vaccines in Different Immune Pathways

Vaccines
Diarrheal disease continues to be a major cause of global morbidity and mortality among children under 5 years of age. To address the current issues associated with oral attenuated rotavirus vaccines, the study of parenteral rotavirus vaccines has ...
Jingping Hu, Jinyuan Wu, Han Cao, Ning Luan, Kangyang Lin, Haihao Zhang, Dandan Gao, Zhentao Lei, Hongjun Li, Cunbao Liu   +9 more
doaj   +1 more source

Molecular Design of Encapsulin Protein Nanoparticles to Display Rotavirus Antigens for Enhancing Immunogenicity

Vaccines
Rotavirus considerably threatens global health, particularly for children
Hyun-Gyo Jung, Seonghun Jeong, Min-Ji Kang, Ingi Hong, Young-Shin Park, Eunbyeol Ko, Jae-Ouk Kim, Deog-Young Choi   +7 more
doaj   +1 more source

Development of a novel bivalent vaccine candidate against hepatitis A virus and rotavirus using reverse vaccinology and immunoinformatics

Journal of Virus Eradication
The hepatitis A virus (HAV) and rotavirus are mainly transmitted through fecal-oral and person-to-person contact, and cause severe gastrointestinal complications and liver disease. This work used reverse vaccinology and immunoinformatic methods to create
Hassan Yarmohammadi, Abbas Akhavan Sepahi, Mojtaba Hamidi-fard, Mohammadreza Aghasadeghi, Golnaz Bahramali   +4 more
doaj   +1 more source

The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca ²⁺

, 2023
ABSTRACT Rotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles from which the DLPs escape.
Marilina De Sautu, Tobias Herrmann, Simon Jenni, Stephen C. Harrison   +3 more
openaire   +2 more sources

Oral immunization of mice with Lactococcus lactis expressing the rotavirus VP8* protein [PDF]

Biotechnology Letters, 2011
The efficacy of recombinant Lactococcus lactis as a delivery vehicle for a rotavirus antigen was evaluated in a mouse model. The rotavirus VP8* protein was expressed intracellularly and extracellularly in L. lactis wild type and in an alr mutant deficient in alanine racemase activity, necessary for the synthesis of the cell-wall component D: -alanine ...
Rodríguez Díaz, Jesús, Montava, Rebeca, Viana, R., Buesa, Javier, Pérez Martínez, Gaspar, Monedero, V.   +5 more
openaire   +3 more sources