Results 11 to 20 of about 2,910 (199)
A Nanoparticle-Based Trivalent Vaccine Targeting the Glycan Binding VP8* Domains of Rotaviruses [PDF]
Viruses, 2021 Rotavirus causes severe gastroenteritis in children. Although vaccines are implemented, rotavirus-related diarrhea still claims ~200,000 lives annually worldwide, mainly in low-income settings, pointing to a need for improved vaccine tactics.
Ming Xia +3 more
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Formulation and preclinical studies with a trivalent rotavirus P2-VP8 subunit vaccine [PDF]
Human Vaccines & Immunotherapeutics, 2020 More effective rotavirus vaccines are essential for preventing extensive diarrheal morbidity and mortality in children under five years of age in low-resource regions. Nonreplicating rotavirus vaccines (NRRV) administered parenterally provide an alternate vaccination method to the current licensed oral vaccine. Live attenuated vaccines and may generate
Kyle Lakatos +3 more
openaire +4 more sources
Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution. [PDF]
PLoS Pathogens, 2017 Recognition of specific cell surface glycans, mediated by the VP8* domain of the spike protein VP4, is the essential first step in rotavirus (RV) infection. Due to lack of direct structural information of virus-ligand interactions, the molecular basis of
Yang Liu +6 more
doaj +2 more sources
Glycan binding patterns of human rotavirus P[10] VP8* protein [PDF]
Virology Journal, 2018 Los rotavirus (RV) son una causa importante de gastroenteritis aguda infantil. El rotavirus P [10] pertenece al genogrupo P[I] de los rotavirus del grupo A que infectan principalmente a los animales, mientras que el rotavirus P [10] se identificó principalmente a partir de la infección humana.
Lili Pang +8 more
openaire +4 more sources
mRNA-based VP8* nanoparticle vaccines against rotavirus are highly immunogenic in rodents
npj Vaccines, 2023 Despite the availability of live-attenuated oral vaccines, rotavirus remains a major cause of severe childhood diarrhea worldwide. Due to the growing demand for parenteral rotavirus vaccines, we developed mRNA-based vaccine candidates targeting the viral
Sandro Roier +5 more
doaj +2 more sources
Viruses, 2022 VP8, the most abundant tegument protein of bovine herpesvirus-1 (BoHV-1), plays an important role in viral replication. According to our previous studies, VP8 localizes to the Golgi apparatus of BoHV-1-infected cells where it can be packaged into the ...
Soumya Sucharita +2 more
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GPU-based VP8 encoding: Performance in native and virtualized environments
2016 International Conference on Telecommunications and Multimedia (TEMU), 2016 A key motivation behind the success of Cloud Computing is that virtualization allows significant energy and cost savings by sharing physical resources. Another source of savings in virtualized architectures is the use of h/w accelerators (e.g. GPUs, FPGAs).
Pietro Paglierani +3 more
openaire +2 more sources
Human Vaccines & Immunotherapeutics, 2019 Non-replicating parenteral rotavirus (RV) vaccine candidates are in development in an attempt to overcome the lower efficacy and effectiveness of oral RV vaccines in low-income countries.
Daniel E. Velasquez, Baoming Jiang
doaj +2 more sources
Comparasion Analysis of Video Quality on Codec VP8 and H.265 PBX Server with Pixel Conversion Method
Jurnal Jaringan Telekomunikasi, 2022 Many studies and research are continuously being developed to improve the quality and capability of video compression. Compression of the video is done with the help of a video codec, in the video there are several types of video codecs including VP8 and
Riza Rosyidah Adi Putri +2 more
doaj +3 more sources
Iranian Journal of MicrobiologyBackground and Objectives: Rotavirus and Hepatitis A virus are responsible for causing gastroenteritis and jaundice. The current vaccination approaches have proven insufficient, especially in low-income countries.
Hassan Yarmohammadi +4 more
doaj +3 more sources