Results 11 to 20 of about 2,319 (158)
Genetic Diversity of Rotavirus Strains in the Era of Vaccination: A Pilot Study from Central Kerala, India [PDF]
Introduction: Rotaviruses cause Acute Gastroenteritis (AGE) in children. Characterisation of rotavirus VP7, VP4 and VP6 genes revealed novel genotypes circulating in the region.
Sincy George +3 more
doaj +1 more source
The Functional Characterization of Bat and Human P[3] Rotavirus VP8*s [PDF]
P[3] rotavirus (RV) has been identified in many species, including human, simian, dog, and bat. Several glycans, including sialic acid, histo-blood group antigens (HBGAs) are reported as RV attachment factors. The glycan binding specificity of different P[3] RV VP8*s were investigated in this study.
Dandi Li +8 more
openaire +2 more sources
Evaluation of an inducible knockout system in insect cells based on co-infection and CRISPR/Cas9.
Due to comparably high product titers and low production costs, the baculovirus/insect cell expression system is considered a versatile production platform in the biopharmaceutical industry.
Christina Sophie Hausjell +3 more
doaj +1 more source
Quorum sensing (QS) is a chemical communication process that bacteria use to track population density and orchestrate collective behaviors. QS relies on the production, accumulation, and group-wide detection of extracellular signal molecules called ...
Olivia P Duddy +3 more
doaj +1 more source
Establishment of Sandwich ELISA for Quality Control in Rotavirus Vaccine Production
Non-replicating rotavirus vaccines are alternative strategies that may improve the protective efficacy of rotavirus vaccines in low- and middle-income countries.
Cao Li +9 more
doaj +1 more source
Expression of bovine rotavirus VP8 and preparation of IgY antibodies against recombinant VP8
Group A rotavirus is the leading cause of acute gastroenteritis in cattle and swine. Although, vaccination against this virus is an effective strategy for prevention, additional strategy to control disease is necessary. Egg yolk immunoglobulin (IgY)-based passive immunization could be a better option in preventing this disease.
H S, Kim, B, Lee, S Y, Han, Y T, Jung
openaire +3 more sources
Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution. [PDF]
Recognition of specific cell surface glycans, mediated by the VP8* domain of the spike protein VP4, is the essential first step in rotavirus (RV) infection. Due to lack of direct structural information of virus-ligand interactions, the molecular basis of
Yang Liu +6 more
doaj +1 more source
VP8, the most abundant tegument protein of bovine herpesvirus-1 (BoHV-1), plays an important role in viral replication. According to our previous studies, VP8 localizes to the Golgi apparatus of BoHV-1-infected cells where it can be packaged into the ...
Soumya Sucharita +2 more
doaj +1 more source
Interaction of VP8 with mRNAs of bovine herpesvirus-1
The UL47 gene product, VP8, is one of the most abundant tegument proteins of bovine herpesvirus-1 (BoHV-1). Deletion of VP8 leads to impaired growth in tissue culture, and VP8 is indispensable for BHV-1 replication in cattle. To elucidate the biological functions of VP8, we explored its interaction with mRNAs of immediate early (bICP0), early (gB, gD ...
Azharul, Islam +4 more
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The VP8 fragment of VP4 is the rhesus rotavirus hemagglutinin
The amino-terminal trypsin cleavage fragment of VP4, called VP8, was expressed from a recombinant baculovirus in Sf-9 cells. The baculovirus-expressed VP8 protein is antigenically conserved as demonstrated by its recognition by a library of neutralizing monoclonal antibodies. In Sf-9 cell sonicates, the expressed VP8 protein is capable of agglutinating
L, Fiore, H B, Greenberg, E R, Mackow
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