Results 21 to 30 of about 3,267 (159)

3D Object Class Detection in the Wild [PDF]

open access: yes, 2015
Object class detection has been a synonym for 2D bounding box localization for the longest time, fueled by the success of powerful statistical learning techniques, combined with robust image representations.
Gehler, Peter   +4 more
core   +1 more source

Vaccinia virions lacking core protein VP8 are deficient in early transcription [PDF]

open access: yesJournal of Virology, 1996
When synthesis of the 25-kDa vaccinia virus core protein VP8 is repressed, mature virus particles of normal appearance are produced to approximately 80% of wild-type levels but these particles are over 100-fold less infectious than wild-type particles (D. Wilcock and G. L. Smith, Virology 202:294-304, 1994). Here we show that virions which lack VP8 can
D, Wilcock, G L, Smith
openaire   +2 more sources

The Vaccinia virion: Filling the gap between atomic and ultrastructure.

open access: yesPLoS Pathogens, 2019
We have investigated the molecular-level structure of the Vaccinia virion in situ by protein-protein chemical crosslinking, identifying 4609 unique-mass crosslink ions at an effective FDR of 0.33%, covering 2534 unique pairs of crosslinked protein ...
Yeva Mirzakhanyan, Paul Gershon
doaj   +1 more source

GARP and EARP are required for efficient BoHV-1 replication as identified by a genome wide CRISPR knockout screen.

open access: yesPLoS Pathogens, 2023
The advances in gene editing bring unprecedented opportunities in high throughput functional genomics to animal research. Here we describe a genome wide CRISPR knockout library, btCRISPRko.v1, targeting all protein coding genes in the cattle genome ...
Wenfang S Tan   +7 more
doaj   +1 more source

On-stack replacement, distilled [PDF]

open access: yes, 2018
On-stack replacement (OSR) is essential technology for adaptive optimization, allowing changes to code actively executing in a managed runtime. The engineering aspects of OSR are well-known among VM architects, with several implementations available to ...
Bhandari Abhilash   +14 more
core   +1 more source

Human VP8* mAbs neutralize rotavirus selectively in human intestinal epithelial cells [PDF]

open access: yesJournal of Clinical Investigation, 2019
We previously generated 32 rotavirus-specific (RV-specific) recombinant monoclonal antibodies (mAbs) derived from B cells isolated from human intestinal resections. Twenty-four of these mAbs were specific for the VP8* fragment of RV VP4, and most (20 of 24) were non-neutralizing when tested in the conventional MA104 cell-based assay.
Ningguo Feng   +11 more
openaire   +2 more sources

Subcellular redistribution and sequential recruitment of macromolecular components during SGIV assembly

open access: yesProtein & Cell, 2016
Virus infection consists of entry, synthesis of macromolecular components, virus assembly and release. Understanding of the mechanisms underlying each event is necessary for the intervention of virus infection in human healthcare and agriculture. Here we
Yongming Yuan, Yunhan Hong
doaj   +1 more source

Transmission of potato spindle tuber viroid between Phytophthora infestans and host plants

open access: yesВавиловский журнал генетики и селекции, 2022
Potato spindle tuber viroid (PSTVd) is a naked, circular, single-stranded RNA (356–363 nucleotides in length) which lacks any protein-coding sequences.
O. S. Afanasenko   +3 more
doaj   +1 more source

Coupling coefficients for coupled-cavity lasers [PDF]

open access: yes, 1987
We derive simple, analytic formulas for the field coupling coefficients in a two-section coupled-cavity laser using a local field rate equation treatment.
Lang, Robert J., Yariv, Amnon
core   +1 more source

The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca2+

open access: yes, 2023
ABSTRACTRotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles from which the DLPs escape.
Marilina De Sautu   +3 more
openaire   +2 more sources

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