Results 21 to 30 of about 2,910 (199)

The Functional Characterization of Bat and Human P[3] Rotavirus VP8*s [PDF]

Virologica Sinica, 2021
P[3] rotavirus (RV) has been identified in many species, including human, simian, dog, and bat. Several glycans, including sialic acid, histo-blood group antigens (HBGAs) are reported as RV attachment factors. The glycan binding specificity of different P[3] RV VP8*s were investigated in this study.
Dandi Li, Mengxuan Wang, Tongyao Mao, Mingwen Wang, Qing Zhang, Hong Wang, Lili Pang, Xiaoman Sun, Zhaojun Duan   +8 more
openaire   +2 more sources

Establishment of Sandwich ELISA for Quality Control in Rotavirus Vaccine Production

Vaccines, 2022
Non-replicating rotavirus vaccines are alternative strategies that may improve the protective efficacy of rotavirus vaccines in low- and middle-income countries.
Cao Li, Guoxing Luo, Yuanjun Zeng, Feibo Song, Han Yang, Shiyin Zhang, Yingbin Wang, Tingdong Li, Shengxiang Ge, Ningshao Xia   +9 more
doaj   +1 more source

Expression of bovine rotavirus VP8 and preparation of IgY antibodies against recombinant VP8

Acta virologica, 2017
Group A rotavirus is the leading cause of acute gastroenteritis in cattle and swine. Although, vaccination against this virus is an effective strategy for prevention, additional strategy to control disease is necessary. Egg yolk immunoglobulin (IgY)-based passive immunization could be a better option in preventing this disease.
H S, Kim, B, Lee, S Y, Han, Y T, Jung
openaire   +3 more sources

Incidence and clinical characteristics of group A rotavirus infections among children admitted to hospital in Kilifi, Kenya [PDF]

, 2008
Background Rotavirus, predominantly of group A, is a major cause of severe diarrhoea worldwide, with the greatest burden falling on young children living in less-developed countries.
Peenze, Ina, Maghenda, J. Kamino, Maitland, Kathryn, J Anthony G Scott, J Kamino Maghenda, Dewar, J, Kathryn Maitland, Scott, John, Allan Pamba, Thomas N Williams, Williams, TN, Maitland, K, Bauni, Evasius, Dewar, John, Scott, J. Anthony G., Hellen Gatakaa, Pamba, A, Evasius Bauni, Williams, Thomas N., Maghenda, J Kamino, John Abwao, Peenze, I, John Dewar, Nokes, D. James, Nokes, DJ, Scott, JA, Bauni, E, Scott, J Anthony G, Williams, Thomas N, D James Nokes, Maghenda, JK, Pamba, Allan, Williams, Thomas, Ina Peenze, Gatakaa, Hellen, Nokes, D James, Abwao, J, Gatakaa, H, Abwao, John, Nokes, TN   +39 more
core   +1 more source

The VP8 fragment of VP4 is the rhesus rotavirus hemagglutinin

Virology, 1991
The amino-terminal trypsin cleavage fragment of VP4, called VP8, was expressed from a recombinant baculovirus in Sf-9 cells. The baculovirus-expressed VP8 protein is antigenically conserved as demonstrated by its recognition by a library of neutralizing monoclonal antibodies. In Sf-9 cell sonicates, the expressed VP8 protein is capable of agglutinating
L, Fiore, H B, Greenberg, E R, Mackow
openaire   +2 more sources

Interaction of VP8 with mRNAs of bovine herpesvirus-1

Virus Research, 2015
The UL47 gene product, VP8, is one of the most abundant tegument proteins of bovine herpesvirus-1 (BoHV-1). Deletion of VP8 leads to impaired growth in tissue culture, and VP8 is indispensable for BHV-1 replication in cattle. To elucidate the biological functions of VP8, we explored its interaction with mRNAs of immediate early (bICP0), early (gB, gD ...
Azharul, Islam, Sandra, Schulz, Sharmin, Afroz, Lorne A, Babiuk, Sylvia, van Drunen Littel-van den Hurk   +4 more
openaire   +2 more sources

Impact of Vaccination on Rotavirus Genotype Diversity: A Nearly Two-Decade-Long Epidemiological Study before and after Rotavirus Vaccine Introduction in Sicily, Italy

Pathogens, 2022
Sicily was the first Italian region to introduce rotavirus (RV) vaccination with the monovalent G1P[8] vaccine Rotarix® in May 2012. In this study, the seasonal distribution and molecular characterization of RV strains detected over 19 years were ...
Floriana Bonura, Leonardo Mangiaracina, Chiara Filizzolo, Celestino Bonura, Vito Martella, Max Ciarlet, Giovanni M. Giammanco, Simona De Grazia   +7 more
doaj   +1 more source

The Vaccinia virion: Filling the gap between atomic and ultrastructure.

PLoS Pathogens, 2019
We have investigated the molecular-level structure of the Vaccinia virion in situ by protein-protein chemical crosslinking, identifying 4609 unique-mass crosslink ions at an effective FDR of 0.33%, covering 2534 unique pairs of crosslinked protein ...
Yeva Mirzakhanyan, Paul Gershon
doaj   +1 more source

GARP and EARP are required for efficient BoHV-1 replication as identified by a genome wide CRISPR knockout screen.

PLoS Pathogens, 2023
The advances in gene editing bring unprecedented opportunities in high throughput functional genomics to animal research. Here we describe a genome wide CRISPR knockout library, btCRISPRko.v1, targeting all protein coding genes in the cattle genome ...
Wenfang S Tan, Enguang Rong, Inga Dry, Simon G Lillico, Andy Law, Paul Digard, Bruce Whitelaw, Robert G Dalziel   +7 more
doaj   +1 more source

Distribution of conserved and specific epitopes on the VP8 subunit of rotavirus VP4 [PDF]

Journal of Virology, 1992
Three cDNA clones comprising the VP8 subunit of the VP4 of human rotavirus strain KU (VP7 serotype G1; VP4 serotype P1A) G1 were constructed. The corresponding encoded peptides were designated according to their locations in the VP8 subunit as A (amino acids 1 to 102), B (amino acids 84 to 180), and C (amino acids 150 to 246 plus amino acids 247 to 251
G, Larralde, M, Gorziglia
openaire   +2 more sources