Results 1 to 10 of about 2,268 (114)

Recent Increase in Rotavirus Gastroenteritis After Five Years of Low Activity in Hokkaido Prefecture, Japan, Associated With Equine-Like G3P[8] and G8P[8] Strains, 2025. [PDF]

J Med Virol
ABSTRACT Rotavirus gastroenteritis decreased substantially worldwide during the COVID‐19 pandemic, and activity remained minimal in Hokkaido Prefecture, Japan, for 5 years after 2020. Hospital‐based surveillance in Hokkaido since July 2019 identified the first resurgence of rotavirus gastroenteritis in 2025.
Fukuda Y, Fujii Y, Togashi A, Nawa T, Nakamura S, Kimura R, Kunizaki J, Ando Y, Nishino K, Kizawa T, Yamamoto D, Iizuka Y, Sasaoka Y, Kikuchi M, Nishikawa K, Nagai K, Asakura H, Shimokawa S, Kabutoya H, Kobayashi S, Tsugawa T.   +20 more
europepmc   +2 more sources

Repeated-dose toxicity and immunogenicity evaluation of norovirus P particle-based rotavirus vaccine in juvenile cynomolgus monkeys [PDF]

Frontiers in Immunology
IntroductionRotavirus remains a major cause of mortality among young children worldwide, underscoring the urgent need for new vaccines. The present study evaluated the repeated-dose toxicity and immunogenicity of a bivalent rotavirus subunit candidate ...
Wei Pan, Wei Pan, Yingjie Cheng, Yingjie Cheng, Xiaojing Shi, Xiaojing Shi, Yunxiang Chen, Yunxiang Chen, Yunxiang Chen, Cong Xu, Cong Xu, Zhengbiao Yang, Zhengbiao Yang, Qijiong Lu, Qijiong Lu, Qijiong Lu, Lei Wen, Lei Wen, Lei Wen, Fang Liu, Fang Liu, Tingli Bian, Tingli Bian, Li Qin, Li Qin, Shuizhen Pan, Shuizhen Pan, Ying Chen, Ying Chen, Changwei Wu, Changwei Wu, Lijiang Zhang, Lijiang Zhang, Lijiang Zhang, Hongzhong Yang, Hongzhong Yang, Hongzhong Yang   +36 more
doaj   +2 more sources

Validity and Reliability of the Heart Rate Matching Task: A Novel Measure of Heart Rate Estimation. [PDF]

Psychophysiology
ABSTRACT Sensing and monitoring changes in our heart rate is a key aspect of interoception. We introduce and test the construct validity of the Heart Rate Matching task (HRM), a novel, fast and accessible task designed to assess the ability to estimate heart rate, in both remote (i.e., online) and in‐lab settings.
Moffatt JA, Tünte MR, Von Mohr M, Tsakiris M.   +3 more
europepmc   +2 more sources

Whole-Genome Characterization of Rare Artiodactyl-Like G10P [14] and G8P [14] Rotavirus a Strains Detected in Pediatric Gastroenteritis Cases in Hokkaido Prefecture, Japan. [PDF]

J Med Virol
ABSTRACT Rotavirus alphagastroenteritidis (RVA) is the leading cause of acute gastroenteritis in young children worldwide, as well as in a wide range of animal species. In 2020 and 2022, we identified three unusual RVA strains in pediatric gastroenteritis patients in Hokkaido Prefecture, Japan, using next‐generation sequencing: one G10P[14] strain ...
Takebayashi A, Fukuda Y, Fujii Y, Nihira H, Kihara M, Kudou Y, Adachi S, Shintani N, Tsugawa T.   +8 more
europepmc   +2 more sources

Different Fc scaffolds enhance the breadth of in vitro neutralization of the same Fab against different Rotavirus strains [PDF]

Frontiers in Immunology
Rotaviruses are the primary cause of severe dehydrating diarrhea in infants and young children globally. Currently, several oral rotavirus vaccines are available; however, they have shown reduced effectiveness and quicker waning of protection in low- and
Mabel Rocio Miranda-Echagüe, Giacomo Vezzani, Elena Morandi, Melania Della Peruta, Mirko Scordio, Teresa Anne Clarisse Reyes, Davide Oldrini, Miren Iturriza-Gómara, Rebecca Jo Loomis, Omar Rossi   +9 more
doaj   +2 more sources

Carp edema virus in Ukraine – The evidence for the furthest east presence of CEV genogroup I in Europe

Aquaculture Reports, 2023
Carp edema virus (CEV) is a poxvirus infecting gills of common carp (Cyprinus carpio) and causes a deadly disease called koi sleepy disease (KSD).
Yuriy Rud, Olga Zaloilo, Leonid Buchatsky, Marek Matras, Dieter Steinhagen, Mikolaj Adamek   +5 more
doaj   +1 more source

Design and Construction of Chimeric VP8-S2 Antigen for Bovine Rotavirus and Bovine Coronavirus [PDF]

Advanced Pharmaceutical Bulletin, 2016
Purpose: Bovine Rotavirus and Bovine Coronavirus are the most important causes of diarrhea in newborn calves and in some other species such as pigs and sheep.
Khadijeh Nasiri, Mohammadreza Nassiri, Mojtaba Tahmoorespour, Alireza Haghparast, Saeed Zibaee   +4 more
doaj   +1 more source

Genetic Diversity of Rotavirus Strains in the Era of Vaccination: A Pilot Study from Central Kerala, India [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Rotaviruses cause Acute Gastroenteritis (AGE) in children. Characterisation of rotavirus VP7, VP4 and VP6 genes revealed novel genotypes circulating in the region.
Sincy George, Ozhiparambil A Jagan, Sushama Bai, Sara Chandy   +3 more
doaj   +1 more source

Evaluation of an inducible knockout system in insect cells based on co-infection and CRISPR/Cas9.

PLoS ONE, 2023
Due to comparably high product titers and low production costs, the baculovirus/insect cell expression system is considered a versatile production platform in the biopharmaceutical industry.
Christina Sophie Hausjell, Miriam Klausberger, Wolfgang Ernst, Reingard Grabherr   +3 more
doaj   +1 more source

Natural silencing of quorum-sensing activity protects Vibrio parahaemolyticus from lysis by an autoinducer-detecting phage.

PLoS Genetics, 2023
Quorum sensing (QS) is a chemical communication process that bacteria use to track population density and orchestrate collective behaviors. QS relies on the production, accumulation, and group-wide detection of extracellular signal molecules called ...
Olivia P Duddy, Justin E Silpe, Chenyi Fei, Bonnie L Bassler   +3 more
doaj   +1 more source