Results 41 to 50 of about 2,910 (199)

Association of biomarkers of enteric dysfunction, systemic inflammation, and growth hormone resistance with seroconversion to oral rotavirus vaccine: A lasso for inference approach.

PLoS ONE, 2023
BackgroundRotavirus gastroenteritis remains a leading cause of morbidity and mortality despite the introduction of vaccines. Research shows there are several factors contributing to the reduced efficacy of rotavirus vaccines in low- and middle-income ...
Katayi Mwila-Kazimbaya, Samuel Bosomprah, Obvious Nchimunya Chilyabanyama, Caroline Cleopatra Chisenga, Mwelwa Chibuye, Natasha Makabilo Laban, Michelo Simuyandi, Bert Huffer, Miren Iturriza-Gomara, Robert K M Choy, Roma Chilengi   +10 more
doaj   +1 more source

Association between Immunogenicity of a Monovalent Parenteral P2-VP8 Subunit Rotavirus Vaccine and Fecal Shedding of Rotavirus following Rotarix Challenge during a Randomized, Double-Blind, Placebo-Controlled Trial

, 2023
A correlate of protection for rotavirus (RV) has not been consistently identified. Shedding of RV following an oral rotavirus vaccine (ORV) challenge has been investigated as a potential model to assess protection of parenteral RV vaccines. We previously
Michelle J. Groome, Nicola Page, Stanley Cryz, Jorge Flores, Alan Fix, Monica McNeal, Miren Iturriza-Gomara, Tamika Fellows   +7 more
core   +1 more source

Specificity and Affinity of Sialic Acid Binding by the Rhesus Rotavirus VP8* Core [PDF]

Journal of Virology, 2002
ABSTRACT Nuclear magnetic resonance spectroscopy demonstrates that the rhesus rotavirus hemagglutinin specifically binds α-anomeric N -acetylneuraminic acid with a K d of 1.2 mM. The hemagglutinin requires no additional carbohydrate moieties
Dormitzer, Philip R., Sun, Zhen-Yu J., Blixt, Ola, Paulson, James C., Wagner, Gerhard, Harrison, Stephen C.   +5 more
openaire   +4 more sources

Mechanism underlying the DNA-binding preferences of the Vibrio cholerae and vibriophage VP882 VqmA quorum-sensing receptors.

PLoS Genetics, 2021
Quorum sensing is a chemical communication process that bacteria use to coordinate group behaviors. In the global pathogen Vibrio cholerae, one quorum-sensing receptor and transcription factor, called VqmA (VqmAVc), activates expression of the vqmR gene ...
Olivia P Duddy, Xiuliang Huang, Justin E Silpe, Bonnie L Bassler   +3 more
doaj   +1 more source

Magnetothermal‐Triggered Response and Self‐Healing of Recyclable and Reprocessable Nanocomposites for Actuation Systems

Advanced Functional Materials, Volume 36, Issue 45, 5 June 2026.
Developing recyclable materials for magnetic robotics that combine rapid response and self‐healing properties is challenging. Hence, this study focuses on the integration of magnetothermal nanoparticles into a dynamic sorbitol‐based vitrimer, a recyclable composite capable of remote actuation and self‐healing by magnetic heating.
Maria Weißpflog, Gloria Signorato, Birgit Hankiewicz, Volker Abetz   +3 more
wiley   +1 more source

A Pseudovirus Nanoparticle-Based Trivalent Rotavirus Vaccine Candidate Elicits High and Cross P Type Immune Response

Pharmaceutics, 2022
Rotavirus infection continues to cause significant morbidity and mortality globally. In this study, we further developed the S60-VP8* pseudovirus nanoparticles (PVNPs) displaying the glycan receptor binding VP8* domains of rotavirus spike proteins as a ...
Ming Xia, Pengwei Huang, Ming Tan
doaj   +1 more source

Vaccinia virions lacking core protein VP8 are deficient in early transcription [PDF]

Journal of Virology, 1996
When synthesis of the 25-kDa vaccinia virus core protein VP8 is repressed, mature virus particles of normal appearance are produced to approximately 80% of wild-type levels but these particles are over 100-fold less infectious than wild-type particles (D. Wilcock and G. L. Smith, Virology 202:294-304, 1994). Here we show that virions which lack VP8 can
D, Wilcock, G L, Smith
openaire   +2 more sources

Simplified schematics of the vibriophage VP882 and Vibrio QS circuits at HCD and mechanisms driving phage VP882 host-cell lysis.

, 2023
(A) Multiple autoinducer-receptor pairs control QS in V. parahaemolyticus. AI-1 (circles), AI-2 (triangles), and CAI-1 (squares) are detected by LuxN, LuxPQ, and CqsS, respectively.
Olivia P. Duddy (9954319), Justin E. Silpe (1317783), Bonnie L. Bassler (41611), Chenyi Fei (10515970)   +3 more
core   +1 more source

Secretion of the rotavirus VP8* protein inLactococcus lactis [PDF]

FEMS Microbiology Letters, 2001
Secretion of the VP8* subunit of the VP4 capsid protein of rotavirus by Lactococcus lactis has been achieved. For this purpose, a secretion vector has been constructed with the lactococcal signal sequence AL9 and the VP8*-encoding gene fragment. The amount of VP8* secreted by L. lactis in the culture supernatant was quantified and visualised by Western
Maria Teresa Gil, Isabel Pérez-Arellano, Javier Buesa, Gaspar Pérez-Martı&#x;nez   +3 more
openaire   +1 more source

Helicoverpa armigera nucleopolyhedrovirus occlusion-derived virus-associated protein, HA100, affects oral infectivity in vivo but not virus replication in vitro

, 2011
ORF100 (ha100) of Helicoverpa armigera nucleopolyhedrovirus (HearNPV) has been reported as one of the unique genes of group II alphabaculoviruses encoding a protein located in the occlusion-derived virus (ODV) envelope and nucleocapsid.
Xushi Xu, Luo, S., Just M. Vlak, Fei Deng, Xu, X., Wang, H., Vlak, J.M., Deng, F., Zhang, Y., Yanfang Zhang, Marcel Westenberg, Sijiani Luo, Westenberg, M., Hu, Z., Hualin Wang, Zhihong Hu   +15 more
core   +1 more source