Results 61 to 70 of about 2,319 (158)

Interaction Between Microbiota and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and New Therapeutic Opportunities

open access: yesMedComm, Volume 6, Issue 7, July 2025.
This review systematically concludes the interaction between microbiota and immunity. We introduce six phyla: Bacteroidetes, Firmicutes, Actinobacteria, Proteobacteria, Fusobacteria, and Verrucomicrobia. We also elucidate molecular mechanisms, biological functions, diseases, and new therapeutic opportunities between microbiota and immunity. .
Jingjing Zeng   +4 more
wiley   +1 more source

Design of multi-epitope vaccine against porcine rotavirus using computational biology and molecular dynamics simulation approaches

open access: yesVirology Journal
Porcine Rotavirus (PoRV) is a significant pathogen affecting swine-rearing regions globally, presenting a substantial threat to the economic development of the livestock sector.
Xiaochen Zhu   +4 more
doaj   +1 more source

Circulating rotavirus strains in children with acute gastroenteritis in Iran, 1986 to 2023 and their genetic/antigenic divergence compared to approved vaccines strains (Rotarix, RotaTeq, ROTAVAC, ROTASIIL) before mass vaccination: Clues for vaccination policy makers

open access: yesVirus Research
In the present study, first, rotaviruses that caused acute gastroenteritis in children under five years of age during the time before the vaccine was introduced in Iran (1986 to 2023) are reviewed.
Somayeh Jalilvand   +7 more
doaj   +1 more source

POLYMERASE CHAIN REACTION FOR CHARACTERIZATION OF VP4 GENE TYPES OF GROUP A BOVINE ROTAVIRUS DIRECTLY IN THE FECES OF NEONATAL DAIRY CALVES [PDF]

open access: yesVeterinary Medical Journal - Giza, 1998
A PCR (polymerase chain reaction) genotyping assay was applied to identify bovine rotavirus (BRV) gene 4 types (P genotypes, NCDV (PI), UK (P5), and B223 (P11) in the field samples collected from calves with and without diarrhoea.
HUSSEIN A. HUSSEIN   +3 more
doaj   +1 more source

Phenotyping, genome‐wide dissection, and prediction of maize root architecture for temperate adaptability

open access: yesiMeta, Volume 4, Issue 2, April 2025.
This study dissects the genetic architecture of maize Root System Architecture, identifying significant root trait differences between tropical/subtropical and temperate lines. Using genome‐wide association study, 3511 genes were linked to root morphology, weight, and slice traits.
Weijun Guo   +7 more
wiley   +1 more source

Eco-alternative treatments for Vibrio parahaemolyticus and V. cholerae biofilms from shrimp industry through Eucalyptus (Eucalyptus globulus) and Guava (Psidium guajava) extracts: A road for an Ecuadorian sustainable economy.

open access: yesPLoS ONE
Understanding how environmental variables influence biofilm formation becomes relevant for managing Vibrio biofilm-related infections in shrimp production.
Nicolás Renato Jara-Medina   +11 more
doaj   +1 more source

Severe Diarrhea Outbreaks in Newborn Piglets in China Associated With Porcine Rotavirus B

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Rotavirus B (RVB) is among the enteric pathogens that can cause gastroenteritis in humans and various animals. However, severe diarrhea in newborn piglets has rarely been reported to be linked to porcine RVB (PoRVB). From 2023 to 2024, outbreaks of newborn piglet diarrhea with 20%–50% morbidity and 4%–10% mortality occurred in three herds situated in ...
Mingkai Sun   +10 more
wiley   +1 more source

Rotavirus A Infection Prevalence and Spatio-Temporal Genotype Shift among Under-Five Children in Amhara National Regional State, Ethiopia: A Multi-Center Cross-Sectional Study

open access: yesVaccines
Background: Globally, rotavirus (RV) A (RVA) is the most common cause of severe and sometimes fatal diarrhea in young children. It is also the major cause of acute gastroenteritis among children in Ethiopia.
Debasu Damtie   +9 more
doaj   +1 more source

Evolution of P[8], P[4], and P[6] VP8* genes of human rotaviruses globally reported during 1974 and 2017: possible implications for rotavirus vaccines in development

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Non-replicating parenteral rotavirus (RV) vaccine candidates are in development in an attempt to overcome the lower efficacy and effectiveness of oral RV vaccines in low-income countries.
Daniel E. Velasquez, Baoming Jiang
doaj   +1 more source

Biotechnological Interventions for the Production of Subunit Vaccines Against Group A Rotavirus

open access: yesCell Biochemistry and Function, Volume 42, Issue 8, December 2024.
ABSTRACT Group A rotavirus (RVA) is a major cause of severe gastroenteritis in infants and young children globally, despite the availability of live‐attenuated vaccines. Challenges such as limited efficacy in low‐income regions, safety concerns for immunocompromised individuals, and cold‐chain dependency necessitate alternative vaccine strategies ...
Mukta Prajapati   +10 more
wiley   +1 more source

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