Results 51 to 60 of about 16,455 (176)
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase. [PDF]
PLoS Pathogens, 2007 Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) has been shown to cause G2 cell cycle arrest in human cells by inducing ATR-mediated inactivation of p34cdc2, but factors directly engaged in this process remain unknown.
Jean-Philippe Belzile +5 more
doaj +1 more source
Women's land ownership in Victoria, 1880–1930: Contributions to a fuller picture
Asia‐Pacific Economic History Review, EarlyView.Abstract Responding to calls for more research on Australian women's property ownership this article draws on underutilised shire rate books. The data challenge stubborn historiographical assumptions that women's land ownership in federation‐era Victoria was insignificant.
Kathryn M. Hunter
wiley +1 more source
The Journal of Cell Biology, 2001 ![][1] Nuclear holes allow Wee1 to escape (top, left to right) and Cdc25C to enter (bottom) the nucleus. Greene/AAAS The Vpr protein from HIV-1 makes holes in the nucleus, according to Warner Greene (Gladstone Institute of Virology and Immunology, University of California ...
openaire +2 more sources
The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, R90. [PDF]
PLoS ONE, 2009 BACKGROUND: A hallmark of AIDS progression is a switch of cytokines from Th1 to Th2 in the plasma of patients. IL-12, a critical Th1 cytokine secreted by antigen presenting cells (APCs) is suppressed by Vpr, implicating it as an important virulence ...
Irina Tcherepanova +8 more
doaj +1 more source
International Journal of Dental Hygiene, EarlyView.ABSTRACT Objectives This study aimed to investigate the relationship between functional independence, oral hygiene habits and periodontal status in patients with Down syndrome (DS). Methods A cross‐sectional observational study was conducted with 49 patients with Down Syndrome. Sociodemographic data, oral hygiene habits and functional independence were
Joana Albuquerque Bastos de Sousa +6 more
wiley +1 more source
Anti-cancer effect of HIV-1 viral protein R on doxorubicin resistant neuroblastoma.
PLoS ONE, 2010 Several unique biological features of HIV-1 Vpr make it a potentially powerful agent for anti-cancer therapy. First, Vpr inhibits cell proliferation by induction of cell cycle G2 arrest.
Richard Y Zhao +4 more
doaj +1 more source
HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction. [PDF]
PLoS ONE, 2012 Human immunodeficiency virus 1 (HIV-1) viral protein R (Vpr) has been shown to induce host cell death by increasing the permeability of mitochondrial outer membrane (MOM).
Chih-Yang Huang +4 more
doaj +1 more source
eFood, Volume 7, Issue 4, August 2026.Pulsed electric field (PEF) processing qualitatively reshapes the phytochemical profile of red beet extracts, resulting in enhanced endothelial bioefficacy. Compared with conventional extraction, PEF‐treated extracts more effectively restore nitric oxide signaling, suppress endothelial inflammation, and normalize vascular structure in high‐fat diet ...
Eunju Jang +8 more
wiley +1 more source
Virology Journal, 2011 Background Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) is a virion-associated regulatory protein that functions at several points within the viral life cycle and has been shown to accumulate primarily in the nucleus and at the ...
Ferrucci Adriano +2 more
doaj +1 more source
International Migration, Volume 64, Issue 4, July 2026.ABSTRACT The global increase in displaced populations underscores the need for diverse refugee solutions, with Western countries expanding resettlement and sponsorship programmes. Sponsorship programmes, involving private and community actors in refugee support, are often credited with offering more comprehensive, personalised assistance than ...
Gabriella D'Avino
wiley +1 more source