Results 81 to 90 of about 26,217 (212)
, 2013 (A) Analysis of vpr-1 genetic mosaics showing the lineages of major tissues. Each circle indicates one genetic mosaic worm. Points at which the genomic copy of vpr-1(+) was lost and the resulting phenotype are shown.
Hajer El Oussini (454743) +8 more
core +1 more source
HIV-1 Vpr Affects Alternative Splicing by Modulating SRPK Activity [PDF]
, 2022 Alternative splicing, an essential post-transcriptional mechanism, is a target for HIV. HIV employs this process to produce multiple viral proteins from a single mRNA.
William, Karen A
core +1 more source
Virology Journal, 2011 Background Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) is a virion-associated regulatory protein that functions at several points within the viral life cycle and has been shown to accumulate primarily in the nucleus and at the ...
Ferrucci Adriano +2 more
doaj +1 more source
HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction. [PDF]
PLoS ONE, 2012 Human immunodeficiency virus 1 (HIV-1) viral protein R (Vpr) has been shown to induce host cell death by increasing the permeability of mitochondrial outer membrane (MOM).
Chih-Yang Huang +4 more
doaj +1 more source
Wildlife Biology, EarlyView.Obtaining accurate information on demographic states, such as the age and sex classes of animals, is an important step for monitoring wildlife populations. Traditionally, demographic data are collected from harvest, aerial surveys and telemetry studies.
Alexej P. K. Sirén +15 more
wiley +1 more source
De Novo Expressed Vpr Stimulates HIV-1 Replication in T Cells
VirusesVpr, a virion-associated accessory virulence factor of HIV-1, promotes virus replication in both T cells and macrophages. Although Vpr’s early activity—antagonism of preintegration silencing and host restriction factors—has been documented, the relative ...
Blessing Enya, Jacek Skowronski
doaj +1 more source
Anti-cancer effect of HIV-1 viral protein R on doxorubicin resistant neuroblastoma.
PLoS ONE, 2010 Several unique biological features of HIV-1 Vpr make it a potentially powerful agent for anti-cancer therapy. First, Vpr inhibits cell proliferation by induction of cell cycle G2 arrest.
Richard Y Zhao +4 more
doaj +1 more source
International Journal of Dental Hygiene, EarlyView.ABSTRACT Objectives This study aimed to investigate the relationship between functional independence, oral hygiene habits and periodontal status in patients with Down syndrome (DS). Methods A cross‐sectional observational study was conducted with 49 patients with Down Syndrome. Sociodemographic data, oral hygiene habits and functional independence were
Joana Albuquerque Bastos de Sousa +6 more
wiley +1 more source
mBio, 2019 How Vpr enhances HIV-1 replication in macrophages is still unclear. We report here that Vpr enhanced HIV-1 Env processing during the first round of HIV-1 replication, resulting in virions with higher Env incorporation and viral infectivity.
Qi Wang, L. Su
semanticscholar +1 more source
Journal of Esthetic and Restorative Dentistry, EarlyView.ABSTRACT Objective To evaluate the effect of glazing dwell time and cooling duration on the flexural strength and surface microhardness of high‐translucency 3 mol% yttria‐stabilized tetragonal zirconia polycrystal (3Y‐TZP). Materials and Methods Total of 108 rectangular zirconia specimens (20 × 4 × 2 mm) were fabricated from preshaded monolithic blocks
Shubha Sarmalkar +5 more
wiley +1 more source