Results 91 to 100 of about 20,255 (238)
PLoS Pathogens, 2006 The human immunodeficiency virus (HIV) type-1 viral protein U (Vpu) protein enhances the release of diverse retroviruses from human, but not monkey, cells and is thought to do so by ablating a dominant restriction to particle release. Here, we determined
Stuart J D Neil +3 more
doaj +2 more sources
The HIV-1 Vpu protein induces apoptosis in Drosophila via activation of JNK signaling.
PLoS ONE, 2012 The genome of the human immunodeficiency virus type 1 (HIV-1) encodes the canonical retroviral proteins, as well as additional accessory proteins that enhance the expression of viral genes, the infectivity of the virus and the production of virions.
Christelle Marchal +7 more
doaj +1 more source
Bio-Protocol, 2021 This protocol details a rapid and reliable method for the production and titration of high-titre viral pseudotype particles with the SARS-CoV-2 spike protein (and D614G or other variants of concern, VOC) on a lentiviral vector core, and use for ...
Cecilia Di Genova +17 more
doaj +1 more source
Journal of Virology, 2020 The HIV-1 accessory protein Vpu enhances viral spread by downregulating CD4 and BST-2/tetherin on the surface of infected cells. Natural variability in these Vpu functions may contribute to HIV-1 pathogenesis, but this has not been investigated among the
G. Umviligihozo +18 more
semanticscholar +1 more source
HIV‐1 viral protein effect on cerebral microvasculature: An in vitro blood–brain barrier model
Physiological Reports, Volume 13, Issue 19, October 2025.Abstract The central nervous system (CNS) serves as a sanctuary for the Human Immunodeficiency Virus (HIV), which is facilitated by HIV's ability to breach the blood–brain barrier (BBB). BBB dysfunction occurs in the earliest stages of an HIV‐1 infection.
Sinelisiwe Matubatuba +5 more
wiley +1 more source
Neural Architecture Search for Intel Movidius VPU
, 2023 Hardware-aware Neural Architecture Search (NAS) technologies have been proposed to automate and speed up model design to meet both quality and inference efficiency requirements on a given hardware. Prior arts have shown the capability of NAS on hardware specific network design. In this whitepaper, we further extend the use of NAS to Intel Movidius VPU (
Xu, Qian, Li, Victor, S, Crews Darren
openaire +2 more sources
Effects of Vpu Expression onXenopusOocyte Membrane Conductance
Virology, 1998 The HIV-1-specific vpu gene encodes an integral membrane phosphoprotein which affects three aspects of the HIV-1 infectious cycle: it enhances virion release from infected cells; it causes degradation of the CD4 protein in the endoplasmic reticulum; and it delays syncytia formation in HIV-1-infected CD4+ T-cells.
Coady, Michael J. +6 more
openaire +2 more sources
Functional complementation of a model target to study Vpu sensitivity. [PDF]
PLoS ONE, 2013 HIV-1 forms infectious particles with Murine Leukemia virus (MLV) Env, but not with the closely related Gibbon ape Leukemia Virus (GaLV) Env. We have determined that the incompatibility between HIV-1 and GaLV Env is primarily caused by the HIV-1 ...
Sanath Kumar Janaka +2 more
doaj +1 more source
Journal of Biological Chemistry, 2020 Host proteins with antiviral activity have evolved as first-line defenses to suppress viral replication. The HIV-1 accessory protein viral protein U (Vpu) enhances release of the virus from host cells by down-regulating the cell-surface expression of the
A. Waheed +5 more
semanticscholar +1 more source
Phase Transitions in a Kinetic Flocking Model of Cucker-Smale Type [PDF]
, 2016 We consider a collective behavior model in which individuals try to imitate each others' velocity and have a preferred speed. We show that a phase change phenomenon takes place as diffusion decreases, bringing the system from a “disordered” to an ...
Barbaro, ABT +3 more
core +1 more source