Results 71 to 80 of about 20,255 (238)

Variability of VPU protein in HIV-1 sub-subtype A6 in patients with different stages of HIV infection

HIV Infection and Immunosuppressive Disorders
The aim of the study: to compare the genetic diversity of the Vpu protein in HIV-1 in the people living with HIV (PLWH) with different stages of the disease.Materials and methods.
A. Antonova, A. Lebedev, E. Kazennova, K. V. Kim, E. Ozhmegova, A. Tumanov, Yana M. Munchak, E. Orlova-Morozova, A. Pronin, A. Prilipov, A. Kuznetsova   +10 more
semanticscholar   +1 more source

In COS cells Vpu can both stabilize tetherin expression and counteract its antiviral activity.

PLoS ONE, 2014
The interferon-inducible cellular protein tetherin (CD317/BST-2) inhibits the release of a broad range of enveloped viruses. The HIV-1 accessory protein Vpu enhances virus particle release by counteracting this host restriction factor.
Abdul A Waheed, Nishani D Kuruppu, Kathryn L Felton, Darren D'Souza, Eric O Freed   +4 more
doaj   +1 more source

Identification of residues in the BST-2 TM domain important for antagonism by HIV-1 Vpu using a gain-of-function approach

Frontiers in Microbiology, 2011
The HIV-1 Vpu protein enhances the release of viral particles from the cell surface in a cell-type specific manner. In the absence of Vpu, nascent virions remain tethered to the cell surface in restricted cell types. Recently, the human host factor BST-2/
Takeshi eYoshida, Sandra eKao, Klaus eStrebel   +2 more
doaj   +1 more source

Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue

Retrovirology, 2010
Background The human immunodeficiency virus type 1 (HIV-1) Vpu protein degrades CD4 and counteracts a restriction factor termed tetherin (CD317; Bst-2) to enhance virion release.
Specht Anke, Iwanski Alicja, Koppensteiner Herwig, Wimmer Peter, Banning Carina, Rajan Devi, Schindler Michael, Sauter Daniel, Dobner Thomas, Kirchhoff Frank   +9 more
doaj   +1 more source

Performance analysis and optimization of automatic speech recognition [PDF]

, 2018
© 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes,creating new ...
Arnau Montañés, José María, González Colás, Antonio María, Tabani, Hamid, Tubella Murgadas, Jordi   +3 more
core   +2 more sources

Sex‐Specific Factors Influencing HIV Infection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley   +1 more source

Association of Vpu-Binding Protein with Microtubules and Vpu-Dependent Redistribution of HIV-1 Gag Protein

Virology, 2001
The efficient exit of HIV-1 particles from cells requires the action of the viral encoded protein Vpu. Vpu-binding protein (Ubp) is a cellular protein that interacts with both Vpu and the major structural component of the viral capsid (Gag) and appears to affect the efficiency of particle exit. Elucidation of the function of Ubp and characterization of
Handley, Mark A., Paddock, Steve, Dall, Aaron, Panganiban, Antonito T.   +3 more
openaire   +2 more sources

Differentiable River Routing for End‐to‐End Learning of Hydrological Processes

Journal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 1, February 2026.
Abstract Deep Learning (DL) approaches have shown high accuracy in rainfall runoff modeling. Currently, however, large‐scale DL hydrological simulations at national and global scales still rely on external routing schemes to propagate runoff outputs through river networks, preventing them from leveraging the benefits of end‐to‐end learning of ...
Tristan Hascoet, Victor Pellet, Satoru Oishi, Takemasa Miyoshi   +3 more
wiley   +1 more source

Knowledge-Aided STAP Using Low Rank and Geometry Properties [PDF]

, 2013
This paper presents knowledge-aided space-time adaptive processing (KA-STAP) algorithms that exploit the low-rank dominant clutter and the array geometry properties (LRGP) for airborne radar applications.
de Lamare, Rodrigo C., Li, Xiang, Wang, Hongqiang, Yang, Zhaocheng   +3 more
core   +2 more sources

Recent Developments in HIV Antivirals: The Prospect of Prophylactic Drugs to Change the Pandemic

Microbial Biotechnology, Volume 19, Issue 2, February 2026.
Replication cycle of HIV‐1. The scheme provides an overview from virus entry over reverse transcription of viral RNA into viral DNA, provirus DNA integration into the host genome, genome expression by transcription and translation, proteolytic processing of the viral polyproteins, viral maturation to viral release from the cell. The various targets for
Harald Brüssow
wiley   +1 more source