Results 71 to 80 of about 8,539 (222)
Recent Developments in HIV Antivirals: The Prospect of Prophylactic Drugs to Change the Pandemic
Replication cycle of HIV‐1. The scheme provides an overview from virus entry over reverse transcription of viral RNA into viral DNA, provirus DNA integration into the host genome, genome expression by transcription and translation, proteolytic processing of the viral polyproteins, viral maturation to viral release from the cell. The various targets for
Harald Brüssow
wiley +1 more source
Mixed Env trimers can be Vpu sensitive.
Sensitivity to Vpu of each complementation pair is indicated. The degree of Vpu sensitivity is indicated within parentheses as a ratio of infectivity in the absence of Vpu to infectivity in the presence of Vpu.
Jared Faurot (428469) +2 more
core +1 more source
Primate Swallowing Is Powered by Both Rotation and Contraction of Suprahyoid Muscles
ABSTRACT Objectives Swallowing biomechanics in primates and other mammals is poorly understood, and the effect of hyoid descent on swallowing biomechanics lacks experimental interrogation. In macaques, which share similar swallowing kinematics with humans, the base of the tongue and the food bolus are hypothesized to be driven into the oropharynx by a ...
Courtney P. Orsbon +2 more
wiley +1 more source
HIV-1 Vpu acts positively on viral infectivity by mediating CD4 degradation in endoplasmic reticulum and enhances virion release by counteracting a virion release restriction factor, tetherin.
Masako Nomaguchi +4 more
doaj +1 more source
Expression of the Rev1-Vpu fusion protein.
(A) Western blot analysis of HEK293T cells co-transfected with the proviral clones described in Fig 1A or a vpu-deficient mutant thereof. Expression vectors containing rev1-vpu or vpu cassettes served as size controls. Vpu and Rev1-Vpu were detected with
Simon M. Langer (824158) +7 more
core +1 more source
The Vpu accessory protein promotes HIV-1 release by counteracting Tetherin/BST-2, an interferon-regulated restriction factor, which retains virions at the cell-surface.
Mathieu Dubé +6 more
doaj +1 more source
Anti-tetherin activities in Vpu-expressing primate lentiviruses
Background The anti-viral activity of the cellular restriction factor, BST-2/tetherin, was first observed as an ability to block the release of Vpu-minus HIV-1 from the surface of infected cells.
Haworth Kevin G +5 more
doaj +1 more source
VPU literatūros rašinio ir publicistikos konkurso nuostatai
Šie nuostatai apibrėžia VPU skiriamų premijų ...
core

