Results 51 to 60 of about 8,539 (222)
Evaluation of Varnishes to Slow Down the Aging of Plasticized PVC
Varnish effectiveness in plasticized PVC strongly depends on both formulation and degradation state. A polyurethane varnish effectively limits color change and plasticizer loss in unaged PVC without phosphate plasticizers, whereas no protective effect is observed for phosphate‐containing PVC.
Mathilde Larrieu +5 more
wiley +1 more source
Mechanisms underlying HIV-1 Vpu-mediated viral egress [PDF]
Viruses such as lentiviruses that are responsible for long lasting infections, have to evade several level of cellular immune mechanisms to persist and efficiently disseminate in the host.
Katy eJanvier +11 more
core +1 more source
Functional complementation of a model target to study Vpu sensitivity. [PDF]
HIV-1 forms infectious particles with Murine Leukemia virus (MLV) Env, but not with the closely related Gibbon ape Leukemia Virus (GaLV) Env. We have determined that the incompatibility between HIV-1 and GaLV Env is primarily caused by the HIV-1 ...
Sanath Kumar Janaka +2 more
doaj +1 more source
Effects of Vpu Expression onXenopusOocyte Membrane Conductance [PDF]
The HIV-1-specificvpugene encodes an integral membrane phosphoprotein which affects three aspects of the HIV-1 infectious cycle: it enhances virion release from infected cells; it causes degradation of the CD4 protein in the endoplasmic reticulum; and it
Tiganos, Evangelos +6 more
core +1 more source
The intrinsic immunity factor CD317 (BST-2/HM1.24/tetherin) imposes a barrier to HIV-1 release at the cell surface that can be overcome by the viral protein Vpu.
Sarah Schmidt +4 more
doaj +1 more source
This protocol details a rapid and reliable method for the production and titration of high-titre viral pseudotype particles with the SARS-CoV-2 spike protein (and D614G or other variants of concern, VOC) on a lentiviral vector core, and use for ...
Cecilia Di Genova +17 more
doaj +1 more source
Human immunodeficiency virus (HIV) allosteric integrase inhibitors (ALLINIs) offer a vital alternative to standard therapies by targeting noncatalytic sites. By inducing aberrant integrase multimerization, they disrupt viral maturation. This review explores their medicinal chemistry evolution, detailing structural insights, structure–activity ...
Francesco Saccoliti +10 more
wiley +1 more source
Polarity changes in the transmembrane domain core of HIV-1 Vpu inhibits its anti-tetherin activity.
Tetherin (BST-2/CD317) is an interferon-inducible antiviral protein that restricts the release of enveloped viruses from infected cells. The HIV-1 accessory protein Vpu can efficiently antagonize this restriction.
Mingyu Lv +6 more
doaj +1 more source
Smart Sensing Systems For Agricultural Plant Health Monitoring: Current State and Prospects
Smart plant sensing technologies are critically evaluated across contact and non‐contact modalities, fabrication strategies, and diagnostic capabilities. Key deployment challenges and future research directions are identified, revealing pathways toward scalable, field‐ready systems that enable reliable, real‐time plant health monitoring and accelerate ...
Frank Efe Erukainure +1 more
wiley +1 more source
HLA-C Downmodulation by HIV-1 Vpu [PDF]
It is widely held that HIV-1 Nef downmodulates HLA-A and -B to protect infected cells from CD8(+) T cells but leaves HLA-C on the cell surface to inhibit NK cells. In this issue of Cell Host & Microbe, Apps et al. (2016) revise this model by showing that the Vpu protein of primary HIV-1 isolates downmodulate HLA-C.
Edward, Barker, David T, Evans
openaire +2 more sources

