Results 51 to 60 of about 8,539 (222)

Evaluation of Varnishes to Slow Down the Aging of Plasticized PVC

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 43, November 15, 2026.
Varnish effectiveness in plasticized PVC strongly depends on both formulation and degradation state. A polyurethane varnish effectively limits color change and plasticizer loss in unaged PVC without phosphate plasticizers, whereas no protective effect is observed for phosphate‐containing PVC.
Mathilde Larrieu   +5 more
wiley   +1 more source

Mechanisms underlying HIV-1 Vpu-mediated viral egress [PDF]

open access: yes, 2014
Viruses such as lentiviruses that are responsible for long lasting infections, have to evade several level of cellular immune mechanisms to persist and efficiently disseminate in the host.
Katy eJanvier   +11 more
core   +1 more source

Functional complementation of a model target to study Vpu sensitivity. [PDF]

open access: yesPLoS ONE, 2013
HIV-1 forms infectious particles with Murine Leukemia virus (MLV) Env, but not with the closely related Gibbon ape Leukemia Virus (GaLV) Env. We have determined that the incompatibility between HIV-1 and GaLV Env is primarily caused by the HIV-1 ...
Sanath Kumar Janaka   +2 more
doaj   +1 more source

Effects of Vpu Expression onXenopusOocyte Membrane Conductance [PDF]

open access: yes, 1998
The HIV-1-specificvpugene encodes an integral membrane phosphoprotein which affects three aspects of the HIV-1 infectious cycle: it enhances virion release from infected cells; it causes degradation of the CD4 protein in the endoplasmic reticulum; and it
Tiganos, Evangelos   +6 more
core   +1 more source

HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction

open access: yesmBio, 2011
The intrinsic immunity factor CD317 (BST-2/HM1.24/tetherin) imposes a barrier to HIV-1 release at the cell surface that can be overcome by the viral protein Vpu.
Sarah Schmidt   +4 more
doaj   +1 more source

Production, Titration, Neutralisation, Storage and Lyophilisation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lentiviral Pseudotypes

open access: yesBio-Protocol, 2021
This protocol details a rapid and reliable method for the production and titration of high-titre viral pseudotype particles with the SARS-CoV-2 spike protein (and D614G or other variants of concern, VOC) on a lentiviral vector core, and use for ...
Cecilia Di Genova   +17 more
doaj   +1 more source

Targeting Human Immunodeficiency Virus Integrase Beyond the Active Site: The Discovery and Development of Allosteric Integrase Inhibitors

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Human immunodeficiency virus (HIV) allosteric integrase inhibitors (ALLINIs) offer a vital alternative to standard therapies by targeting noncatalytic sites. By inducing aberrant integrase multimerization, they disrupt viral maturation. This review explores their medicinal chemistry evolution, detailing structural insights, structure–activity ...
Francesco Saccoliti   +10 more
wiley   +1 more source

Polarity changes in the transmembrane domain core of HIV-1 Vpu inhibits its anti-tetherin activity.

open access: yesPLoS ONE, 2011
Tetherin (BST-2/CD317) is an interferon-inducible antiviral protein that restricts the release of enveloped viruses from infected cells. The HIV-1 accessory protein Vpu can efficiently antagonize this restriction.
Mingyu Lv   +6 more
doaj   +1 more source

Smart Sensing Systems For Agricultural Plant Health Monitoring: Current State and Prospects

open access: yesAdvanced Sensor Research, Volume 5, Issue 8, August 2026.
Smart plant sensing technologies are critically evaluated across contact and non‐contact modalities, fabrication strategies, and diagnostic capabilities. Key deployment challenges and future research directions are identified, revealing pathways toward scalable, field‐ready systems that enable reliable, real‐time plant health monitoring and accelerate ...
Frank Efe Erukainure   +1 more
wiley   +1 more source

HLA-C Downmodulation by HIV-1 Vpu [PDF]

open access: yesCell Host & Microbe, 2016
It is widely held that HIV-1 Nef downmodulates HLA-A and -B to protect infected cells from CD8(+) T cells but leaves HLA-C on the cell surface to inhibit NK cells. In this issue of Cell Host & Microbe, Apps et al. (2016) revise this model by showing that the Vpu protein of primary HIV-1 isolates downmodulate HLA-C.
Edward, Barker, David T, Evans
openaire   +2 more sources

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