Results 41 to 50 of about 8,539 (222)

Potential Vpu cofactors: STRING relationships and co-localization with Vpu.

open access: yes, 2021
(A) The interactions of proteins in k-means cluster 6 (Fig 6) were visualized using the STRINGdb (Cytoscape) network analysis tool. The clusters of interrelated proteins identified represent candidate Vpu cofactors.
Sumit K. Chanda (11768006)   +11 more
core   +1 more source

The HIV-1 Vpu protein induces apoptosis in Drosophila via activation of JNK signaling.

open access: yesPLoS ONE, 2012
The genome of the human immunodeficiency virus type 1 (HIV-1) encodes the canonical retroviral proteins, as well as additional accessory proteins that enhance the expression of viral genes, the infectivity of the virus and the production of virions.
Christelle Marchal   +7 more
doaj   +1 more source

Enhancing Lentiviral Purification: Combining CIM QA Monolithic Columns With Design of Experiments Approach

open access: yesELECTROPHORESIS, EarlyView.
Lentiviral vector purification using QA CIM monolith anion‐exchange chromatography was optimized via 96‐well and DOE, increasing recovery from 20% to 90%. The process achieved 3.3‐log host cell protein reduction, decreased particle impurities, and showed high binding capacity, supporting large‐scale manufacturing.
Luka Bevc   +7 more
wiley   +1 more source

Fault‐Specific Diagnostic Regions Based on Normalized DC Voltage and Current Indices for Photovoltaic Systems Using Routine Inverter and Environmental Data

open access: yesEnergy Science &Engineering, EarlyView.
This study proposes a fault diagnostic approach for photovoltaic systems using normalized DC voltage and current indices derived from routinely collected inverter and environmental data. The approach enables string‐ and array‐level fault diagnosis without additional measurement equipment and supports operation and maintenance decision‐making.
Woo Gyun Shin   +5 more
wiley   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

open access: yesThe FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini   +4 more
wiley   +1 more source

HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane.

open access: yesPLoS Pathogens, 2006
The human immunodeficiency virus (HIV) type-1 viral protein U (Vpu) protein enhances the release of diverse retroviruses from human, but not monkey, cells and is thought to do so by ablating a dominant restriction to particle release. Here, we determined
Stuart J D Neil   +3 more
doaj   +2 more sources

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

open access: yesThe FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo   +8 more
wiley   +1 more source

HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses

open access: yeseLife, 2019
Many viral pathogens target innate sensing cascades and/or cellular transcription factors to suppress antiviral immune responses. Here, we show that the accessory viral protein U (Vpu) of HIV-1 exerts broad immunosuppressive effects by inhibiting ...
Simon Langer   +13 more
doaj   +1 more source

U–Pb Dating of Cambrian Magmatism in the Pinerolo‐Sanfront Unit, Dora‐Maira Massif (Western Alps)

open access: yesTerra Nova, EarlyView.
ABSTRACT The Pinerolo‐Sanfront Unit (PSU), the structurally lowest tectonic unit of the Dora‐Maira Massif (Western Alps), has been regarded as a monocyclic unit composed of Permo‐Carboniferous sediments and Permian granitoids that were metamorphosed during the Alpine orogeny.
Francesco De Cesari   +6 more
wiley   +1 more source

Intersentential Anaphoric Use of Personal Pronouns in English Discourse

open access: yesKalbotyra, 2005
The present article is concerned with the determination and descriptive analysis of the basic patterns of intersentential anaphoric use of personal pronouns in J. Galsworthy’s The Man of Property.
Darija Bartkutė
doaj  

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