Results 101 to 110 of about 20,255 (238)

Comparison of HIV-1 Vif and Vpu accessory proteins for delivery of polyepitope constructs harboring Nef, Gp160 and P24 using various cell penetrating peptides

PLoS ONE, 2019
To develop an effective therapeutic vaccine against HIV-1, prediction of the most conserved epitopes derived from major proteins using bioinformatics tools is an alternative achievement.
Kimia Kardani, A. Hashemi, A. Bolhassani
semanticscholar   +1 more source

Electric Field‐Driven Conformational Changes in Molecular Memristor and Synaptic Behavior

Advanced Science, Volume 12, Issue 23, June 20, 2025.
Self‐assembled monolayers (SAMs) based molecular device is used for the emulation of synaptic functions. The device operates with a novel switching mechanism via incoherent charge transport, inducing conformational changes. With a low energy consumption (8.0 pJ µm−2), the system shows promise for neuromorphic computing, offering potential in low‐energy,
Chanjin Lim, Taegil Kim, YoungJu Park, Daeho Kim, ChaeHo Shin, Suji Ha, Jin‐Liang Lin, Yuan Li, Junwoo Park   +8 more
wiley   +1 more source

HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction

mBio, 2011
The intrinsic immunity factor CD317 (BST-2/HM1.24/tetherin) imposes a barrier to HIV-1 release at the cell surface that can be overcome by the viral protein Vpu.
Sarah Schmidt, Joëlle V. Fritz, Julia Bitzegeio, Oliver T. Fackler, Oliver T. Keppler   +4 more
doaj   +1 more source

Assisted evolution enables HIV-1 to overcome a high trim5α-imposed genetic barrier to rhesus macaque tropism [PDF]

, 2013
Diversification of antiretroviral factors during host evolution has erected formidable barriers to cross-species retrovirus transmission. This phenomenon likely protects humans from infection by many modern retroviruses, but it has also impaired the ...
A Kuroishi, A Lassaux, A Reymond, AM Sheehy, AM Sheehy, B Jia, B Pacheco, B Song, BK Ganser-Pornillos, C Aberham, CA Virgen, CA Virgen, CH Liao, D Blanco-Melo, D Perez-Caballero, D Perez-Caballero, E Battivelli, EE Nakayama, F Zhang, F Zhang, G Brennan, GB Mortuza, GJ Towers, H Yang, HL Wiegand, Jeremy Luban, JW Bainbridge, K Hrecka, KR McCarthy, L Yin, M Pizzato, M Stremlau, M Stremlau, M Stremlau, M Stremlau, M Veillette, MJ Perron, MJ Perron, MR Auerbach, MW McNatt, MW Yap, MW Yap, N Van Damme, O Pornillos, Paul D. Bieniasz, R Mariani, RM Newman, S Cowan, S Ohkura, S Ohkura, S Sebastian, Sam J. Wilson, SB Kutluay, Sebla B. Kutluay, SJ Neil, SJ Rihn, SJ Wilson, SJ Wilson, SJ Wilson, SL Sawyer, Steven J. Soll, SY Lim, T Hatziioannou, T Hatziioannou, T Hatziioannou, T Hatziioannou, T Hatziioannou, Theodora Hatziioannou, V Zennou, X Yu, Y Soneoka, YH Zheng, YJ Zhang, Z Ambrose, Z Keckesova, Z Kratovac   +75 more
core   +3 more sources

In‐Sensor Computing‐Based Smart Sensing Architecture Implemented Using a Dual‐Gate Metal‐Oxide Thin‐Film Transistor Technology

Advanced Electronic Materials, Volume 11, Issue 9, June 2025.
A smart sensor architecture combining an array of sensing elements with an overlapping array of computing and memory elements thus emulates an innervated peripheral sensing system (IPSS) capable of local and autonomous neuromorphic in‐sensor data pre‐processing is presented. Compatibility of the proposed architecture with functionally distinct elements
Tengteng Lei, Yushen Hu, Xinying Xie, Runxiao Shi, Man Wong   +4 more
wiley   +1 more source

Transient-mediated fate determination in a transcriptional circuit of HIV [PDF]

, 2007
Steady-state behavior and bistability have been proposed as mechanisms for decision-making in gene circuits. However, transient gene expression has also been proposed to control cell fate with the decision arbitrated by the lifetime of the expression ...
Leor Weinberger, Michael Simpson, Roy D. Dar   +2 more
core   +1 more source

Time-frequency analysis of chaotic systems

, 2002
We describe a method for analyzing the phase space structures of Hamiltonian systems. This method is based on a time-frequency decomposition of a trajectory using wavelets.
Chandre, C., Uzer, T., Wiggins, S.
core   +3 more sources

Genetic Evolution Between HIV‐1 Groups M and O: HIV‐1/MO Recombinant Forms

Journal of Medical Virology, Volume 97, Issue 5, May 2025.
ABSTRACT HIV exhibits significant genetic diversity, with genetic recombination being a major evolutionary process. The co‐circulation of HIV‐1/M and HIV‐1/O variants has led to the description of 20 HIV‐1/M+O dual infections since 1998. Despite the genetic divergence between these variants, HIV‐1/M+O dual infections have resulted in the emergence of ...
Alice Moisan, Fabienne Tombette, Jean‐Christophe Plantier   +2 more
wiley   +1 more source

A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction.

PLoS Pathogens, 2012
The HIV-1 accessory protein Vpu counteracts tetherin (BST-2/CD317) by preventing its incorporation into virions, reducing its surface expression, and ultimately promoting its degradation.
Tonya Kueck, Stuart J D Neil
doaj   +1 more source

Expression of HIV-1 Vpu leads to loss of the viral restriction factor CD317/Tetherin from lipid rafts and its enhanced lysosomal degradation.

PLoS ONE, 2013
CD317/tetherin (aka BST2 or HM1.24 antigen) is an interferon inducible membrane protein present in regions of the lipid bilayer enriched in sphingolipids and cholesterol (often termed lipid rafts).
Ruth Rollason, Katie Dunstan, Peter G Billcliff, Paul Bishop, Paul Gleeson, Helen Wise, Paul Digard, George Banting   +7 more
doaj   +1 more source