Results 121 to 130 of about 34,623 (230)

Electrophysiological properties of mesodiencephalic junction neurons projecting to the inferior olive

The Journal of Physiology, EarlyView.
Abstract figure legend Highlights of the main electrophysiological differences between MDJ neurons that project to the IO and those that do not. IO‐projecting neurons fire rebound spikes and are spontaneously active at higher frequencies. The bottom panel shows the anatomical connectivity of the MDJ with both excitatory and newly discovered inhibitory ...
Stijn Voerman, Xiang Wang, Xiaolu Wang, Laurens W. J. Bosman, Robin Broersen, Chris I. De Zeeuw   +5 more
wiley   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

VTA neurons express HCN protein.

, 2012
(A) Immunocytochemical colabeling in VTA tissue for GAD and HCN4, one of the channels expressed in the VTA that produces the Ih, yields examples of GAD(+) neurons that are HCN4(+) (top) or HCN4(−) (bottom), consistent with the physiology.
Brian Toy (148271), Elyssa B. Margolis (148265), Patricia Himmels (148277), Howard L. Fields (148283), Marisela Morales (148280)   +4 more
core   +1 more source

Timing of Cardiac Contractility Modulation Therapy Implementation

Clinical Cardiology, Volume 49, Issue 11, November 2026.
In this retrospective registry analysis, cardiac contractility modulation (CCM) improved functional status and left ventricular ejection fraction whether implanted early or later. Implantation within 12 months after CCM‐eligible heart failure diagnosis might be associated with better survival, greater ejection‐fraction improvement, and fewer heart ...
Goekhan Yuecel, Gamze Yildirim, Kristin Schreiner, Svetlana Hetjens, Konstantinos Giannakopoulos, Abbass Kodeih, Mostafa Khalil, Babak Yazdani, Faeq Husain‐Syed, Daniel Duerschmied, William T. Abraham, Ibrahim Akin, Jürgen Kuschyk   +12 more
wiley   +1 more source

Endoplasmic Reticulum Autophagy Enhancement Alleviates Synaptic Plasticity Dysfunction and Ameliorates Cognitive Impairment in SAE Mice by Relieving STING‐Associated Inhibition of PKM2 Activity

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
In sepsis‐associated encephalopathy (SAE), enhanced micro‐ER‐phagy mediated by Sec62 facilitates the delivery of STING to lysosomes for degradation in hippocampal neurons. This process relieves STING‐mediated inhibition of PKM2 activity, which further modulates cellular energy metabolism indicators including the ATP/ADP and NAD+/NADH ratios ...
Xiaofeng Guo, Daqing Yin, Zhonghua Zhang, Yuanyuan Zhao, Yali Zhang, Ying Jiang, Zhanying Zhao, Tongwen Sun, Feihu Zhou, Xijing Zhang   +9 more
wiley   +1 more source

Johdon laskentatoimen kehittäminen toimintolaskennan avulla : case VTA Tekniikka oy

VTA Tekniikka Oy on raskaan kuljetuskaluston nostolaitteiden ja kuormatilan lämmönsäätölaitteiden maahantuontiin, jälleenmyyntiin sekä niiden asennus-, varaosa- ja huoltopalveluihin erikoistunut yritys. Lisäksi VTA Tekniikka Oy tarjoaa lisäakselistoja ja
Rask, Tiina
core  

GABAergic Network Dysregulation in Alcohol Use Disorder: Receptor–Transporter Interactions Driving the Transition From Goal‐Directed to Compulsive Behaviour

Addiction Biology, Volume 31, Issue 11, November 2026.
Astrocytic GAT3 regulates ambient GABA levels in the globus pallidus externus (GPe). Reduced GAT3 function enhances extrasynaptic GABAergic signalling and disrupts subthalamic nucleus (STN) regulation and cortical signal fidelity.ABSTRACTAlcohol use disorder (AUD) is characterized by a shift from controlled, goal‐directed drinking to compulsive ...
Hannah Aranda, Nathan Jones, Humza Haroon, Doo‐Sup Choi   +3 more
wiley   +1 more source

Alpha1-adrenergic receptor blockade in the VTA modulates fear memories and stress responses

, 2017
Activity of the ventral tegmental area (VTA) and its terminals has been implicated in the Pavlovian associative learning of both stressful and rewarding stimuli. However, the role of the VTA noradrenergic signaling in fear responses remains unclear.
Wojciech B. Solecki, Przewłocki, Ryszard, Szklarczyk-Smolana, Klaudia, Klasa, Adam, Adam Klasa, Kamil Pradel, Pradel, Kamil, Solecki, Wojciech, Klaudia Szklarczyk, Grzegorz Dobrzański, Dobrzański, Grzegorz, Ryszard Przewłocki   +11 more
core   +1 more source

VTA-PnO article v1

This collection contains all experimental protocols associated with the manuscript “A VTA–pontine GABA pathway drives backward locomotion via local and distal inhibition”.
openaire   +1 more source

The VTA Agreement: How Has it Done?

Maine Policy Review, 1993
The dramatic changes in telecommunications in the past decade have caused many states to try new approaches to the regulation of local telephone companies. The "Vermont Telecommunications Agreement" was one of the earliest attempts at such innovative regulatory approaches.
openaire   +2 more sources