Results 31 to 40 of about 34,623 (230)
Aversion or Salience Signaling by Ventral Tegmental Area Glutamate Neurons
iScience, 2018 Summary: Ventral tegmental area (VTA) neurons play roles in reward and aversion. The VTA has, in addition to dopamine neurons, glutamatergic neurons expressing VGluT2.
David H. Root +2 more
doaj +1 more source
Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety
, 2021 International audienceNicotine stimulates dopamine (DA) neurons of the ventral tegmental area (VTA) to establish and maintain reinforcement. Nicotine also induces anxiety through an as yet unknown circuitry.
Deroche-Gamonet, Véronique +46 more
core +1 more source
NeuroImage, 2022 The ventral tegmental area (VTA) is one of the major sources of dopamine in the brain and has been associated with reward prediction, error-based reward learning, volitional drive and anhedonia.
Laurel S. Morris +9 more
doaj +1 more source
Sweetspot Mapping in Deep Brain Stimulation: Strengths and Limitations of Current Approaches
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives Open questions remain regarding the optimal target, or sweetspot, for deep brain stimulation (DBS) in, for example, Parkinson's disease. Previous studies introduced different methods of mapping DBS effects to determine sweetspots. While having a direct impact on surgical targeting and postoperative programming in DBS, these methods ...
Till A. Dembek +7 more
wiley +1 more source
Increased functional coupling between VTA and hippocampus during rest in first-episode psychosis [PDF]
, 2021 Animal models suggest that interactions between the hippocampus and ventral tegmental area (VTA) underlie the onset and etiology of psychosis. While a large body of research has separately characterized alterations in hippocampal and VTA function in ...
Gregory, David F +13 more
core +1 more source
Molecular Brain, 2019 Chronic opiate exposure induces neuroadaptations in the mesocorticolimbic system including ventral tegmental area (VTA) dopamine (DA) neurons, whose soma size is decreased following opiate exposure.
Sarah C. Simmons +2 more
doaj +1 more source
Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano +10 more
wiley +1 more source
Two-Pronged Control of the Dorsal Raphe by the VTA [PDF]
Neuron, 2019 In this issue of Neuron, Li et al. (2019) distinguish two separable GABAergic projections from the ventral tegmental area (VTA) to the dorsal raphe nucleus (DRN), with differential μ-opioid receptor regulation, each targeting different postsynaptic neurons and promoting opposing behavioral states.
Julie A, Kauer, Abigail M, Polter
openaire +2 more sources
Frontiers in Psychiatry, 2018 Increasing evidence shows that the midbrain dopaminergic system is involved in various functions. However, details of the role of the midbrain dopaminergic system in these functions are still to be determined in humans.
Yuko Nakamura +9 more
doaj +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Introduction Deep brain stimulation (DBS) is an effective treatment for refractory obsessive–compulsive disorder (OCD). Neuropsychological assessment contributes to DBS treatment in several ways: it monitors the cognitive safety of the treatment, identifies beneficial or detrimental cognitive side effects and it could aid to explain ...
Tim A. M. Bouwens van der Vlis +7 more
wiley +1 more source