Current Toolset in Predicting Acute Coronary Thrombotic Events: The “Vulnerable Plaque” in a “Vulnerable Patient” Concept [PDF]
Despite major advances in pharmacotherapy and interventional procedures, coronary artery disease (CAD) remains a principal cause of morbidity and mortality worldwide.
Maria Emfietzoglou+5 more
doaj +2 more sources
Insulin resistance, vulnerable plaque and stroke risk in patients with carotid artery stenosis [PDF]
Insulin resistance (IR) is linked to both the vulnerable plaque and the stroke risk. However, the precise extent of this correlation and its impact on stroke risk in carotid artery stenosis patients remain unclear.
Junjie Cao+8 more
doaj +2 more sources
Inflammation and plaque vulnerability [PDF]
AbstractAtherosclerosis is a maladaptive, nonresolving chronic inflammatory disease that occurs at sites of blood flow disturbance. The disease usually remains silent until a breakdown of integrity at the arterial surface triggers the formation of a thrombus.
G K Hansson
exaly +5 more sources
Imaging Inflammation in Patients and Animals: Focus on PET Imaging the Vulnerable Plaque [PDF]
Acute coronary syndrome (ACS) describes a range of conditions associated with the rupture of high-risk or vulnerable plaque. Vulnerable atherosclerotic plaque is associated with many changes in its microenvironment which could potentially cause rapid ...
Benjamin Bartlett+5 more
doaj +2 more sources
Vulnerable Plaque in Patients with Acute Coronary Syndrome: Identification, Importance, and Management [PDF]
MI is a leading cause of morbidity and mortality worldwide. Coronary artery thrombosis is the final pathologic feature of the most cases of acute MI primarily caused by atherosclerotic coronary artery disease. The concept of vulnerable plaque has evolved
Atsushi Sakamoto+12 more
doaj +2 more sources
Finding the Vulnerable Plaque [PDF]
AbstractAt a recent Transcatheter Therapeutics meeting in San Francisco the PROSPECT Trial was presented by Dr. Greg Stone. Prospect stands for Providing Regional Observations to Study Predictors of Events in the Coronary Tree. This was a natural history study of atherosclerosis using multi‐modality intracoronary imaging to prospectively identify ...
C. Richard Conti
openalex +5 more sources
Basic aspects of plaque vulnerability [PDF]
The treatment of acute coronary syndromes, including acute myocardial infarction and unstable angina, has been one of the most successful contributions in the last 20 years to the improvement of medicine. However, we are still unable to predict them, and therefore to prevent occurrence of acute myocardial infarction and/or death.
Antoine Lafont
openalex +4 more sources
Analysis of carotid vulnerable plaque MRI high-risk features and clinical risk factors associated with concomitant acute cerebral infarction [PDF]
Background This study aimed to investigate the correlation between the high-risk characteristics of high-resolution MRI carotid vulnerable plaques and the clinical risk factors and concomitant acute cerebral infarction (ACI).
Yongxiang Tang+11 more
doaj +2 more sources
Vulnerable Plaque, Characteristics, Detection, and Potential Therapies [PDF]
Plaque development and rupture are hallmarks of atherosclerotic vascular disease. Despite current therapeutic developments, there is an unmet necessity in the prevention of atherosclerotic vascular disease. It remains a challenge to determine at an early
Anouar Hafiane
doaj +2 more sources
Vulnerable Plaque Inside Stent
it has been proposed that nonhealing endothelium after percutaneous coronary intervention may allow for insudation of lipids superficial to the stent strut level, especially when the underlying plaque carried a large necrotic core.
Jin‐Man Cho+3 more
openalex +4 more sources