Current Toolset in Predicting Acute Coronary Thrombotic Events: The "Vulnerable Plaque" in a "Vulnerable Patient" Concept. [PDF]
Despite major advances in pharmacotherapy and interventional procedures, coronary artery disease (CAD) remains a principal cause of morbidity and mortality worldwide.
Emfietzoglou M +5 more
europepmc +2 more sources
Computed Tomography Biomarkers of Vulnerable Coronary Plaques [PDF]
An unstable plaque has a high risk of thrombosis and at the same time for a fast progression of the stenosis degree. Also, “high-risk plaque” and “thrombosis-prone plaque” are used as synonym terms for characterization of a vulnerable plaque. The imaging
Nyulas Tiberiu +8 more
doaj +2 more sources
Insulin resistance, vulnerable plaque and stroke risk in patients with carotid artery stenosis. [PDF]
Insulin resistance (IR) is linked to both the vulnerable plaque and the stroke risk. However, the precise extent of this correlation and its impact on stroke risk in carotid artery stenosis patients remain unclear.
Cao J +8 more
europepmc +2 more sources
Imaging Inflammation in Patients and Animals: Focus on PET Imaging the Vulnerable Plaque. [PDF]
Acute coronary syndrome (ACS) describes a range of conditions associated with the rupture of high-risk or vulnerable plaque. Vulnerable atherosclerotic plaque is associated with many changes in its microenvironment which could potentially cause rapid ...
Bartlett B +5 more
europepmc +2 more sources
Circulating protein biomarkers and their association with vulnerable plaque characteristics - a PROSPECT II substudy. [PDF]
Background: In the PROSPECT-II study, near infrared spectroscopy (NIRS) and intravascular ultrasound (IVUS) was used to characterize atherosclerotic plaques in the coronary arteries.
Sharma T +17 more
europepmc +2 more sources
Vulnerable Plaque in Patients with Acute Coronary Syndrome: Identification, Importance, and Management. [PDF]
MI is a leading cause of morbidity and mortality worldwide. Coronary artery thrombosis is the final pathologic feature of the most cases of acute MI primarily caused by atherosclerotic coronary artery disease. The concept of vulnerable plaque has evolved
Sakamoto A +12 more
europepmc +2 more sources
Analysis of carotid vulnerable plaque MRI high-risk features and clinical risk factors associated with concomitant acute cerebral infarction. [PDF]
Background This study aimed to investigate the correlation between the high-risk characteristics of high-resolution MRI carotid vulnerable plaques and the clinical risk factors and concomitant acute cerebral infarction (ACI).
Tang Y +11 more
europepmc +2 more sources
Inflammation mediates the relationship between cardiometabolic index and vulnerable plaque in patients with acute coronary syndrome. [PDF]
Background As a novel indicator reflecting metabolic status and visceral adiposity distribution, the cardiometabolic index (CMI) has gained attention in cardiovascular risk stratification. This investigation employed optical coherence tomography (OCT) to
Yan H +7 more
europepmc +2 more sources
CircHIPK3 targets DRP1 to mediate hydrogen peroxide-induced necroptosis of vascular smooth muscle cells and atherosclerotic vulnerable plaque formation. [PDF]
Li X +9 more
europepmc +2 more sources
Co-existing Hypertension and Hyperhomocysteinemia Increases the Risk of Carotid Vulnerable Plaque and Subsequent Vascular Event: An MR Vessel Wall Imaging Study. [PDF]
Li D +7 more
europepmc +3 more sources

