Results 101 to 110 of about 56,156 (204)

VWF springs into action [PDF]

The Journal of Cell Biology, 2006
![Graphic][1] Extended organelle form (left) is needed for later correct function. CUTLER/ELSEVIERFollowing blood vessel injury, long strings of multimeric von Willebrand's factor (VWF) act as a scaffold for platelets to help staunch bleeding. The VWF strings, 100-μm long or more,
openaire   +1 more source

vWF sequences 2 [PDF]

, 2016
Nexus file containing phased alleles from vWF sequences of Sunda shelf Crocidura.
Handika, Heru, Demos, Terrence C., Thomas C. Giarla (3199704), Maharadatunkamsi (3199695), Heru Handika (3199701), Kevin C. Rowe (223136), Terrence C. Demos (798528), Jacob A. Esselstyn (214666), Rowe, Kevin C., Anang S. Achmadi (3199698), Giarla, Thomas C., Esselstyn, Jacob A., Maharadatunkamsi, Achmadi, Anang S.   +13 more
core   +1 more source

IL-6 Released from Hepatic Stellate Cells Promotes Glycolysis and Migration of HCC Through the JAK1/vWF/TGFB1 Axis

Journal of Hepatocellular Carcinoma
Yifei Zhu,1,* Jiayi Gu,1,* Yuxin Lu,1 Qianying Tao,1 Xinliang Cao,1 Yanqing Zhu,1 Mu-qing Yang,2 Xin Liang1 1Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, School of ...
Zhu Y, Gu J, Lu Y, Tao Q, Cao X, Zhu Y, Yang MQ, Liang X   +7 more
doaj  

Challenges and considerations of genetic testing in von Willebrand disease

Research and Practice in Thrombosis and Haemostasis
von Willebrand disease (VWD) is the most common inherited bleeding disorder characterized by defects in the quantity or function of the von Willebrand factor (VWF).
Omid Seidizadeh, Luciano Baronciani, Flora Peyvandi   +2 more
doaj   +1 more source

Biomarkers of Prothrombotic State and Risk Assessment of Exacerbations in Patients with Chronic Obstructive Pulmonary Disease

International Journal of COPD
Yan Jin,1,2,* Ke Zhu,1,* Shiyu Wu,1 Shiyi He,1 Chao Cao1 1Department of Respiratory and Critical Medicine, Key Laboratory of Respiratory Disease of Ningbo, The First Affiliated Hospital of Ningbo University, Ningbo, People’s Republic of China ...
Jin Y, Zhu K, Wu S, He S, Cao C
doaj  

HETEROGENEITY OF ANTI-VON WILLEBRAND FACTOR (VWF) ANTIBODIES WHICH INHIBIT RISTOCETIN-INDUCED VWF BINDING TO PLATELET GLYCOPROTEIN (GP)Ⅰb [PDF]

, 1989
The epitopes of four anti-vWF monoclonal antibodies (MoAbs), which inhibit antibiotic ristocetin induced vWF binding to GPⅠb, were investigated and compared with each other.
高瀬, 俊夫, 吉岡, 章, 西尾, 健治, 藤村, 吉博, 中井, 寛明, 新家, 興, 金田, 美喜夫, 福井, 弘, 嶋, 緑倫   +8 more
core  

The relationships between disseminated intravascular coagulation and time series change of Von Willebrand factor in patients with out-of-hospital cardiac arrest: a retrospective observational study

Thrombosis Journal
Background Out-of-hospital cardiac arrest (OHCA) is frequently complicated by disseminated intravascular coagulation (DIC), which worsens outcomes. Von Willebrand factor (VWF) is central to haemostasis, and its multimeric size and activity are regulated ...
Yuki Itagaki, Yuki Chiba, Misako Suzuki, Mariko Hayamizu, Hisanori Horiuchi, Mineji Hayakawa   +5 more
doaj   +1 more source

I polimorfismi del gene del fattore Von Willebrand (VWF) modulano l'aumento del VWF, indotto da corticosteroidi, nella sindrome di Cushing [PDF]

, 2009
Cushing's Syndrome (CS) is associated with a hypercoagulable state, mainly due to a cortisol-induced increase in von Willebrand factor (VWF) and factor VIII (FVIII) levels. The condition increases the cardiovascular risk in CS patients, predisposing them
Daidone, Viviana
core  

CRISPR-Cas9 knockout of CLU results in decreased VWF protein expression VWF mRNA. [PDF]

A CRISPR-Cas9 knockout HUVEC cell line (CLUKO) demonstrated significant decreases in CLU expression as measured by PCR compared to a mock/control CRISPR-Cas9 HUVEC cell line (2A).
Allaura A. Cox (17980027), Alice Liu (4814415), Christopher J. Ng (14290358)   +2 more
core   +1 more source

Clusterin knockdown has effects on intracellular and secreted von Willebrand factor in human umbilical vein endothelial cells.

PLoS ONE
Alterations in von Willebrand factor (VWF) have an important role in human health and disease. Deficiency of VWF is associated with symptoms of bleeding and excesses of VWF are associated with thrombotic outcomes.
Allaura A Cox, Alice Liu, Christopher J Ng   +2 more
doaj   +1 more source