Results 91 to 100 of about 60,545 (283)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Reduced survival of type 2B von Willebrand factor, irrespective of large multimer representation or thrombocytopenia

Haematologica, 2010
Background Type 2B von Willebrand factor (VWF) is characterized by gain of function mutations in the A1 domain inducing a greater affinity for platelet GPIb, possibly associated with the disappearance of large VWF multimers and thrombocytopenia.Design ...
Alessandra Casonato, Lisa Gallinaro, Maria Grazia Cattini, Elena Pontara, Roberto Padrini, Antonella Bertomoro, Viviana Daidone, Antonio Pagnan   +7 more
doaj   +1 more source

Reference intervals for active VWF and other VWF parameters in 120 healthy individuals.

, 2019
Reference intervals for active VWF and other VWF parameters in 120 healthy individuals.
Jasper A. Remijn (6331226), Hilde Kelchtermans (12561), Philip G. de Groot (167182), Lisa N. van der Vorm (6331220), Dana Huskens (211452), Walid Chayouâ (6331223), Bas de Laat (339246), Li Li (14993), Mark Roest (377867)   +8 more
core   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

Summary of 8 mAbs to VWF and their effects on VWF proteolysis by ADAMTS13.

, 2013
Summary of 8 mAbs to VWF and their effects on VWF proteolysis by ADAMTS13.
Ningzheng Dong (328283), Changgeng Ruan (328282), Jingyu Zhang (256203), Yiming Zhao (348349), Zhenni Ma (328280), Jian Su (86223), Anyou Wang (281729), Fang Liu (13271), Fei Shen (348351)   +8 more
core   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Impact of extracorporeal membrane oxygenation treatments on acquired von Willebrand syndrome in patients with out-of-hospital cardiac arrest: a retrospective observational study

Thrombosis Journal
Background Von Willebrand factor (vWF) plays a crucial role in hemostasis, acting as a key factor for platelet adhesion/aggregation and as a transport protein for coagulation factor VIII. vWF is secreted as a giant multimer, and it undergoes shear stress-
Yuki Chiba, Kota Goto, Misako Suzuki, Hisanori Horiuchi, Mineji Hayakawa   +4 more
doaj   +1 more source

vWF Alignment

, 2013
Nexus file containing phased alleles from vWF sequences of Javan Crocidura.
Jacob A. Esselstyn (214666), Anang S. Achmadi (3199698), Evans, Ben J., Esselstyn, Jacob A., Maharadatunkamsi, -, Siler, Cameron D., Ben J. Evans (270416), - Maharadatunkamsi (3245379), Cameron D. Siler (618179), Achmadi, Anang S.   +9 more
core   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source