Results 81 to 90 of about 60,545 (283)

Factor H binds to VWF.

open access: yes, 2013
(A) Purified VWF (20 nM) was incubated with different concentrations of fH (30, 60 nM) and immunoprecipitated (IP) using anti-VWF antibody or control IgG. VWF co-precipitated proteins were immunoblotted using anti-fH antibody.
Vahid Afshar-Kharghan (450560)   +8 more
core   +1 more source

Comparative Transcriptional Profiling of Key Macrophage and Fibroblast Subpopulations in Rheumatoid Arthritis–Associated Lung Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib   +8 more
wiley   +1 more source

O-glycan determinants regulate VWF trafficking to Weibel-Palade bodies. [PDF]

open access: yes
Von Willebrand factor (VWF) undergoes complex post-translational modification within endothelial cells (EC) prior to secretion. This includes significant N- and O-linked glycosylation.
Petra E Bürgisser (18770413)   +7 more
core   +4 more sources

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

open access: yesBMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu   +8 more
wiley   +1 more source

Value of vWF-related indicators in the diagnosis of liver cirrhosis progression in patients with hepatitis B [PDF]

open access: yesZhenduanxue lilun yu shijian
Objective To evaluate the correlation between von Willebrand factor (vWF) and its related indicators and the progression of liver cirrhosis in patients with hepatitis B and explore the diagnostic value of vWF-related indicators in assisting the diagnosis
YANG Mingkang, LIU Yu, XU Guanqun, WANG Jianbiao, WANG Xuefeng, LIANG Qian
doaj   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

open access: yesBMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li   +6 more
wiley   +1 more source

Von Willebrand Factor and ADAMTS13 in COVID-19 and Beyond: A Question of Balance

open access: yesEuropean Medical Journal Nephrology, 2021
von Willebrand factor (VWF) is a large, adhesive, multimeric protein involved in haemostasis. The larger the size (or number of VWF multimers), the greater the functionality of the protein. A deficiency or defect in VWF can lead to von Willebrand disease
Emmanuel J Favaloro   +2 more
doaj  

Autosomal dominant C1149R von Willebrand disease: phenotypic findings and their implications

open access: yesHaematologica, 2009
Background Mutation C1149R in the von Willebrand factor (VWF) gene has been thought to cause autosomal dominant severe type 1 von Willebrand disease (VWD).Design and Methods Eight patients from three unrelated families with this mutation were included in
Almudena Pérez-Rodríguez   +5 more
doaj   +1 more source

Binding of recombinant full-length and truncated fH molecules to VWF and VWF-A2.

open access: yes, 2013
(A) Recombinant GST VWF-A2 protein (100 nM) was mixed with recombinant full-length or truncated fH (30 nM) and precipitated using glutathione agarose beads.
Vahid Afshar-Kharghan (450560)   +8 more
core   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

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