Results 131 to 140 of about 69,458 (313)

Adhesive properties of the carbohydrate-modified von Willebrand factor (CHO-vWF) [PDF]

, 1988
AB Federici, Christophe de Romeuf, PG de Groot, Bruno Samor, R Lombardi, Patrizia d’Alessio, Claudine Mazurier, PM Mannucci, JJ Sixma   +8 more
openalex   +1 more source

A Von Willebrand Faktor multimer- és konformáció függő aktivitása és a vascularis haematologia = The structure and conformation dependent activity of VWF and its implications on vascular haematology [PDF]

, 2010
A von Willebrand faktor (VWF) egy nagy molekulatömegű azonos alegységekből felépülő glikoprotein, mely alegységenként kollagén és thrombocyták számára szolgáló kötőhellyel is rendelkezik.
Budainé Dr. Tóth, Judit, Elek, Norbert, Fazakas, Ferenc, Hársfalvi, Jolán, Kellermayer, Miklós Sándor Zoltán, Mendelboum, Shlomit, Nagy, Béla, Schlammadinger, Ágota, Szabó, István, Szántó, Tímea, Tornai, István, Udvardy, Miklós László   +11 more
core  

Single‐cell sequencing reveals the role of IL‐33+ endothelial subsets in promoting early gastric cancer progression

iMeta, EarlyView.
A single‐cell atlas was established to reveal the molecular characteristics of early gastric cancer (EGC). In combination with organoids, animal models, and clinical samples, it was found that subpopulations such as pit mucous‐like cell (PMC‐like), proliferating cell (PC), CH25H+ CD4+ T cell, IL‐33+ endothelial cell, and ADAMTSL2+ endothelial cell are ...
Li Zhou, Mei Yang, Chao Deng, Manqiu Hu, Suhua Wu, Kewen Lai, Lili Zhang, Zhiji Chen, Qin Tang, Qingliang Wang, Lu Chen, Runmin Zha, Yuanyuan Chen, Yibo Tan, Song He, Zhihang Zhou   +15 more
wiley   +1 more source

Natural progression and prediction markers in non‐clinically significant oesophageal varices in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Limited literature exists on non‐clinically significant varices (nCSV) and progression in children with portal hypertension (PHT). This study investigates trends and associations in this cohort. Methods This retrospective cohort study analysed 70 children with nCSV undergoing surveillance endoscopy between January 2012 and 2024 ...
Cody Chan, Akshat Goel, Robert Hegarty, Bethany Tucker, Vandana Jain, Eirini Kyrana, Tassos Grammatikopoulos   +6 more
wiley   +1 more source

Substrate‐Dependent Variability in Viability and Angiogenic Marker Expression Among Three Endothelial Cell Subtypes: Insights for Artificial Tissue Vascularization

Macromolecular Bioscience, EarlyView.
The study investigates how four ECM‐mimicking biomaterials—fibrin, fibronectin, and non‐crosslinked or crosslinked gelatin—affect different types of human endothelial cells. Cell viability, morphology, and angiogenic marker expression are evaluated. Results reveal substrate‐dependent effects on cell behavior and emphasize the importance of selecting ...
Jernej Vajda, Boštjan Vihar, Marko Milojević, Dragana Bjelić, Amadeja Brečko, Uroš Maver   +5 more
wiley   +1 more source

Identification of two mutations (Arg611Cys and Arg611His) in the A1 loop of von Willebrand factor (vWF) responsible for type 2 von Willebrand disease with decreased platelet-dependent function of vWF [see comments] [PDF]

, 1995
Lysiane Hilbert, Christine Gaucher, Claudine Mazurier   +2 more
openalex   +1 more source

Complications at Diagnosis of Pediatric Chronic Myeloid Leukemia in Chronic Phase

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Chronic myeloid leukemia (CML) is uncommon during the first two decades of life, resulting in limited experience of pediatricians in handling this leukemia. This is even more true when it comes to managing rare complications at the time of diagnosis.
Nirmalya Roy Moulik, Uma Athale, Markus Metzler, Frederic Millot, Meinolf Suttorp   +4 more
wiley   +1 more source

AJvW-2, an Anti-vWF Monoclonal Antibody, Inhibits Enhanced Platelet Aggregation Induced by High Shear Stress in Platelet-Rich Plasma From Patients With Acute Coronary Syndromes [PDF]

, 1999
Koji Eto, Takaaki Isshiki, Hiroshi Yamamoto, Satoshi Takeshita, Masahiko Ochiai, Naoyuki Yokoyama, Ryota Yoshimoto, Yasuo Ikeda, Tomohide Sato   +8 more
openalex   +1 more source

Quantitative Systems Pharmacology Modeling of Platelet Responses to Recombinant ADAMTS13 in Patients With Congenital Thrombotic Thrombocytopenic Purpura

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, life‐threatening thrombotic microangiopathy caused by a severe inherited deficiency of ADAMTS13, a von Willebrand factor (VWF) cleaving enzyme. Inadequate clinical endpoint data often make it challenging to statistically power clinical trials in ultra‐rare diseases ...
Cameron McBride, Jiaolong Jiang, Zhiwei Zhang, John Tolsma, Parth Patwari, Björn Mellgård, Majid Vakilynejad, Indranil Bhattacharya, Andy Z. X. Zhu   +8 more
wiley   +1 more source

Decreased multidrug resistance protein 1 and increased platelet activation in obstructive sleep apnea syndrome

Sleep Research, EarlyView.
There was a positive correlation between apnea/hypopnea index (AHI) index and platelet aggregation and a negative correlation between CD42b and multidrug resistance protein 1 (MRP1). Platelet activation was high while MRP1 expression was low in severe obstructive sleep apnea syndrome (OSAS) independent of smoking, age, and gender.
Cigdem Bayram Gurel, Engin Korkmaz, Suzan Adin Cinar, Gülsel Ayaz, Bulent Tutluoglu, Gunnur Deniz, Arzuhan Koç, Turgut Ulutin, Gonul Kanigur   +8 more
wiley   +1 more source