Results 151 to 160 of about 252,763 (309)

Verruciform Xanthoma Within the Cyst Lining of Hidradenitis Suppurativa

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Verruciform xanthoma (VX) is a rare lesion most often seen in the oral mucosa or anogenital region, most commonly characterized histologically by verrucous epithelial hyperplasia and foamy histiocytes in the papillary dermis. While VX has been reported in association with inflammatory dermatoses such as lichen planus and lichen sclerosus, its ...
Deaquan Nichols   +4 more
wiley   +1 more source

A UK key opinion leader perspective: Navigating the immunological and logistical transformation brought by stem cell‐derived islets for the treatment of type 1 diabetes

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims To explore UK key‐opinion leader perspectives on the future role of stem cell‐derived islets (sc‐islets) in islet transplantation for people with type 1 diabetes (T1D). Methods Four UK‐based key‐opinion leaders evaluated current limitations of donor islet transplantation and reviewed emerging evidence, clinical pathways and logistical ...
Thomas Strakosch, Shareen Forbes
wiley   +1 more source

Synergistic Continuous and Short Fiber Reinforcement in Additively Manufactured Poly(Ether Ether Ketone) Composites

open access: yesPolymer Composites, Volume 47, Issue 3, Page 2178-2192, 10 February 2026.
Synergistic Composite: Fabrication and Evaluation of Continuous and Chopped Fiber Reinforced PEEK Matrix. ABSTRACT Enhancing the mechanical properties of 3D‐printed thermoplastic composites has become a critical focus in advanced manufacturing, particularly for high‐performance materials like PEEK.
Altuğ Uşun   +2 more
wiley   +1 more source

Reducing low‐dose exposure in helical TomoTherapy for locally advanced left‐sided breast cancer with a deformable image registration–based dose‐mimicking workflow

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 2, February 2026.
Abstract Background Helical TomoTherapy provides highly conformal dose distributions for breast irradiation but is limited by extensive low‐dose spillage (“low‐dose bath”), contributing to increased integral dose and potential long‐term toxicities. Complete blocks can suppress low‐dose spread, but at the cost of prolonged treatment times on legacy ...
Chih‐Chieh Chang   +2 more
wiley   +1 more source

The response of rare CFTR mutations to specific modulator combinations

open access: yesERJ Open Research
Background The combination of the cystic fibrosis transmembrane conductance regulator (CFTR) modulators elexacaftor (VX-445)–tezacaftor (VX-661)–ivacaftor (VX-770) (ETI) enables the effective rescue of CFTR function in people with the F508del mutation ...
Noemie Stanleigh   +13 more
doaj   +1 more source

Rhein Inhibits NLRP3 Activation and Alleviates Microglial Pyroptosis After Intracerebral Hemorrhage in Rats

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
Rhein treatment inhibits NLRP3 inflammasome activation, suppresses Caspase‐1/GSDMD‐mediated pyroptosis, reduces pro‐inflammatory cytokine release, promotes M2 polarization, and improves behavioral outcomes of ICH. These findings suggest that rhein protects against ICH‐induced brain injury through the inhibition of NLRP3‐dependent pyroptosis ...
Adalaiti Aimaiti   +7 more
wiley   +1 more source

Unraveling the Mechanism of Action, Binding Sites, and Therapeutic Advances of CFTR Modulators: A Narrative Review

open access: yesCurrent Issues in Molecular Biology
Cystic fibrosis (CF) is a recessive genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) protein, a chloride and bicarbonate channel localized on the plasma membrane of epithelial cells.
Debora Baroni
doaj   +1 more source

Toward a Green Polymerization of Lignin‐Derived Monomers in Ethyl Lactate Solution or Aqueous Emulsion

open access: yesMacromolecular Materials and Engineering, Volume 311, Issue 2, February 2026.
Starting from lignin‐derived compounds (LDCs), a library of radically polymerizable monomers are synthesized. Biobased polymers are then prepared by free radical polymerization using industrially relevant processes: in solution (ethyl lactate) and in emulsion (water). Polymers with high thermal resistance and tunable Tgs are obtained, along with stable
Joanna Michalska‐Walkowiak   +5 more
wiley   +1 more source

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