Results 141 to 150 of about 27,703 (234)

Zdhhc14 promotes pyroptosis in the dorsal root ganglion of oxaliplatin‐induced peripheral neuropathy mice by enhancing GBP5 palmitoylation and suppressing its ubiquitination

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
Oxaliplatin‐induced up‐regulation of Zdhhc14 enhances GBP5 stability through palmitoylation‐dependent inhibition of ubiquitin–proteasome degradation, thereby contributing to the development of peripheral neuropathy. Zdhhc14 is identified as a key palmitoyltransferase up‐regulated in oxaliplatin‐induced peripheral neuropathy.
Xiao Jiang, Wanqiu Li, Yanzhuo Liu, Wei Song, Xuedan Zheng, Liu Tang   +5 more
wiley   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, Volume 183, Issue 22, Page 6607-6626, November 2026.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

HIV‐associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise

HIV Medicine, Volume 27, Issue 11, Page 1753-1762, November 2026.
Abstract Objective To review the pathogenesis, epidemiology, clinical presentation, management and outcomes of HIV‐associated nephropathy (HIVAN), with emphasis on global disparities, genetic susceptibility (APOL1) and emerging therapeutic and technological advances.
Deepak V. Pathiyil, Nicola Wearne, Brendon Price, Frank Post, Dami A. Collier   +4 more
wiley   +1 more source

A Practical Guide to First‐Principles Calculations for Pseudocapacitive Materials: From Electrochemical Experiments to Atomistic Understanding

ChemElectroChem, Volume 13, Issue 20, 16 October 2026.
Electrochemical experiments reveal what happens, whereas first principles calculations explain why. Emerging computational electrochemistry is bridging these perspectives, enabling quantitative understanding of electrode/electrolyte interfaces and enabling the rational design of next‐generation energy storage materials.
Kenji Oqmhula, Ryo Maezono, Kenta Hongo
wiley   +1 more source

Inward motions of the compact SiO masers around VX Sagittarii

, 2006
We report Very Long Baseline Array (VLBA) observations of 43 GHz upsilon = 1, J = 1-0 SiO masers in the circumstellar envelope of the M-type semiregular variable star VX Sgr at three epochs during 1999 April-May.
Kamohara, R, Imai, H, Shen, ZQ, Chen, X
core  

Indirect Detection of Novichok Nerve Agents A-230, A-232, and A-234 by Ion Mobility Spectrometry: Limitations of Hydrolysis-Based Marker Strategies. [PDF]

Anal Chem
Allers M, Ahrens A, Hitzemann M, Zimmermann S, Ficks A.   +4 more
europepmc   +1 more source

Programme for Furioso & VX 18504, Adelaide, SA, 1995.

, 1995
Programme for VX 18504 and Furioso performed in 1995 at The Playhouse, Adelaide Festival Centre, Adelaide ...
Australian Dance Theatre
core  

Suzetrigine Is Not Expected to Have Clinically Relevant DDIs with Apixaban and Rivaroxaban Based on PBPK Modeling. [PDF]

J Clin Pharmacol
Wang G, Lakota E, Feng B, Jiang L, Liang G, Hare B.   +5 more
europepmc   +1 more source

Functional Proteomics and Biological Screening of Protein Misfolding Under ER Stress Conditions in a Neuroblastoma Cell Model. [PDF]

Curr Issues Mol Biol
Serra A, Morretta E, Pecoraro M, Monti MC, Pascale M, Franceschelli S.   +5 more
europepmc   +1 more source

Novichok A‑230: Monitoring of Provisional Airborne Exposure Levels. [PDF]

ACS Omega
Grisham C, Koll K, Paalhar S, Gay B, Stilley B, Eichelberger N, Deardorff M, Youngren C, Mikowlski R, Durnal E.   +9 more
europepmc   +1 more source