Results 121 to 130 of about 24,286 (193)

General trends in the calnexin-dependent expression and pharmacological rescue of clinical CFTR variants. [PDF]

Elife
Tedman A, Olson JA, Kim M, Foye C, Jackson JJ, McDonald EF, McKee AG, Noguera K, Kuntz CP, Meiler J, Oliver KE, Plate L, Schlebach JP.   +12 more
europepmc   +1 more source

The role of gasdermin-mediated mitochondrial RNA release in amplifying secondary immune response during microbial infection. [PDF]

Front Immunol
Afaq U, Qudus MS, Liu S, Wu K, Chen Y, Tian M, Wu J.   +6 more
europepmc   +1 more source

Miltirone promotes pyroptosis via increasing pyroptosis-related protein NLRP3 and AIM2 in kidney renal clear cell carcinoma. [PDF]

Front Immunol
Huang T, Wang Q, Gao Y, Wang H, Guo C, Song L, He P, Cai J.   +7 more
europepmc   +1 more source

Expanding the targeted protein degradation approach with small molecule chimeras directed to the 26S proteasome. [PDF]

Nat Commun
Casasampere M, Carneros H, Roda T, Zuin A, Gallisà-Suñé N, González-Artero A, Coll-Martínez B, Abad JL, Alqahtani A, Casas J, Fernández-Nogueira P, Delgado A, Bujons J, Fabriàs G, Crosas B.   +14 more
europepmc   +1 more source

L467F;F508del Complex Allele in a Heterozygous State with CFTRdele2,3: What to Expect from CFTR Modulators? [PDF]

Int J Mol Sci
Kondratyeva E, Efremova A, Melyanovskaya Y, Krasnova M, Milovanov M, Shchagina O, Stepanova A, Voronkova A, Sherman V, Kutsev S, Goldshtein D.   +10 more
europepmc   +1 more source

Pyroptosis in epilepsy: from pathophysiological mechanisms to therapeutic strategies. [PDF]

Front Cell Dev Biol
Chen Q, Yang YT, Cai L, Zhang HQ, Yang J.   +4 more
europepmc   +1 more source

Structure-based identification of Jervine as a potent dual-targeting inhibitor of cell cycle kinases. [PDF]

Front Pharmacol
Sulaimani MN, Imtiyaz K, Hassan MI, Husain FM, Rathi A, Farooq MO, Ashraf A, Dohare R, Sohal SS, Noor S.   +9 more
europepmc   +1 more source

New Role of Protein Misfolding Corrector in the ER Stress-Inflammation Axis: Possible Therapeutic Indication in Neuronal and Epithelial Tumor Cells. [PDF]

Int J Mol Sci
Pecoraro M, Serra A, Lamberti MJ, Pascale M, Franceschelli S.   +4 more
europepmc   +1 more source

Functional, Cohort-Level Assessment of CFTR Modulator Responses Using Biobanked Nasal Epithelial Cells from Individuals with Cystic Fibrosis. [PDF]

J Pers Med
Aalbers BL, Amatngalim GD, Aarts EM, Rodenburg LW, den Hertog-Oosterhoff LA, Heijerman HGM, Beekman JM.   +6 more
europepmc   +1 more source

Targeting Na_v Channels for Pain Relief: Structural Insights and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Xie Y, Huang X, Lu F, Huang J.
europepmc   +1 more source