Functional Proteomics and Biological Screening of Protein Misfolding Under ER Stress Conditions in a Neuroblastoma Cell Model. [PDF]
Serra A +5 more
europepmc +1 more source
A pre‐installation virtual commissioning platform for the Korea Light Source ID10 hard X‐ray nanoprobe couples browser‐based Monte Carlo ray tracing, EPICS/Bluesky control and a multilingual natural‐language agent (98.2% accuracy in Korean, English and Japanese) under a zero‐change hardware transition principle, producing commissioning design inputs ...
Minho Seo +9 more
wiley +1 more source
Verruciform Xanthoma of the Buccal Mucosa: A Case Report Highlighting a Rare Architectural Variant and Diagnostic Challenge. [PDF]
Shah B +4 more
europepmc +1 more source
Chronic intermittent hypoxia (CIH) induces early myocardial remodeling and senescence‐associated injury without overt systolic failure in young mice. Aging‐related susceptibility, modeled in vivo by Tert−/− mice and in vitro by D‐gal‐treated primary cardiomyocytes, amplifies CIH‐associated cardiac dysfunction and cellular injury.
Yinghui Su +4 more
wiley +1 more source
The Caspase 1 Inhibitor VX-765 Protects the Isolated Rat Heart via the RISK Pathway
PURPOSE: Protecting the heart from ischaemia-reperfusion (IR) injury is a major goal in patients presenting with an acute myocardial infarction. Pyroptosis is a novel form of cell death in which caspase 1 is activated and cleaves interleukin 1β.
Petrucci, O +4 more
core
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter +20 more
wiley +1 more source
Unraveling the therapeutic mechanisms of Huanglian Jiedu Tang in bacterial meningitis: A comprehensive approach integrating network pharmacology, molecular docking, and experimental validation. [PDF]
Xiao Y, Tong X.
europepmc +1 more source
Colombia and other tropical regions face a very high threat from torrential floods, which have resulted in over 25,000 deaths in a single event. Unfortunately, there is no comprehensive assessment methodology to zone and determine the magnitude of these disasters; therefore, this research aims to help fill this gap.
Carlos A. Buenahora Ballesteros +2 more
wiley +1 more source
Impact of Solvent Choice on SERS Sensing: Solvent-Analyte and Solvent-Substrate Effects for Organophosphate and Nerve Agent Detection. [PDF]
Öberg R +4 more
europepmc +1 more source
Antioxidants Differentially Regulate Non‐Photochemical Quenching
ABSTRACT Non‐photochemical quenching (NPQ) dissipates excess light energy as heat, limiting reactive oxygen species production during photosynthesis. Exogenous antioxidants are widely reported to improve plant performance under stress, yet their impacts on NPQ are inconsistent across studies, complicating mechanistic interpretation.
Aline de Rodrigues de Queiroz +5 more
wiley +1 more source

