Results 161 to 170 of about 24,286 (193)
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Archives of Environmental Contamination and Toxicology, 2005
VX is one of the most toxic chemical warfare agents. Its low volatility and its persistence in the environment raise the issue of long-term exposure risks, either by inhalation or by transdermal penetration. Therefore, a topic of acute interest is the fate of VX in preservative environmental surfaces. In this work, the fate of VX in asphalt pavement, a
S, Gura +4 more
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VX is one of the most toxic chemical warfare agents. Its low volatility and its persistence in the environment raise the issue of long-term exposure risks, either by inhalation or by transdermal penetration. Therefore, a topic of acute interest is the fate of VX in preservative environmental surfaces. In this work, the fate of VX in asphalt pavement, a
S, Gura +4 more
openaire +2 more sources
Speciation of VX in Aqueous Solutions
The Journal of Physical Chemistry C, 201331P and 13C NMR studies of the toxic chemical warfare agent VX [O-ethyl S-(2-N,N′-(diisopropylamino)ethyl) methylphosphonothioate] have been used to understand the reactivity in a wide variety of matrices. The presence of protonated VX has been invoked in many mechanisms of VX degradation and decontamination.
Willliam R. Creasy +2 more
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Journal of Hazardous Materials
VX, a well-known organophosphorus nerve agent (OPNA), poses a significant threat to public safety if employed by terrorists. Obtaining complete metabolites is critical to unequivocally confirm its alleged use/exposure and elucidate its whole-molecular metabolism.
Pei-Yu, Jiang +7 more
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VX, a well-known organophosphorus nerve agent (OPNA), poses a significant threat to public safety if employed by terrorists. Obtaining complete metabolites is critical to unequivocally confirm its alleged use/exposure and elucidate its whole-molecular metabolism.
Pei-Yu, Jiang +7 more
openaire +2 more sources
Current opinion in investigational drugs (London, England : 2000), 2005
Vertex and Mitsubishi are developing VX-950 (LY-570310), the lead compound from a program of small-molecule inhibitors of the hepatitis C virus (HCV) NS3 protease, for the potential treatment of HCV infection. In November 2004, Vertex initiated a phase Ib European trial of VX-950 for the treatment of HCV infection.
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Vertex and Mitsubishi are developing VX-950 (LY-570310), the lead compound from a program of small-molecule inhibitors of the hepatitis C virus (HCV) NS3 protease, for the potential treatment of HCV infection. In November 2004, Vertex initiated a phase Ib European trial of VX-950 for the treatment of HCV infection.
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Connective Tissue Research
Caspase-1 inhibition is a promising option for degenerative joint diseases such as osteoarthritis; however, there is still a long way to go toward clinical use. One of the open challenges is associated with the non-inflammatory role of this caspase in the inflammatory environment as well as under physiological conditions.
Barbora Vesela +6 more
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Caspase-1 inhibition is a promising option for degenerative joint diseases such as osteoarthritis; however, there is still a long way to go toward clinical use. One of the open challenges is associated with the non-inflammatory role of this caspase in the inflammatory environment as well as under physiological conditions.
Barbora Vesela +6 more
openaire +2 more sources
Chemical & Engineering News Archive, 2005
THE ARMY'S CONTROVERSIAL and problem-plagued plan to destroy VX nerve agent stored at Newport, Ind., just hit another snag: The waste by-product of VX neutralization is flammable. Under current plans, the Army would neutralize VX at Newport and transport the by-product, called hydrolysate, to a DuPont facility in New Jersey for secondary treatment and ...
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THE ARMY'S CONTROVERSIAL and problem-plagued plan to destroy VX nerve agent stored at Newport, Ind., just hit another snag: The waste by-product of VX neutralization is flammable. Under current plans, the Army would neutralize VX at Newport and transport the by-product, called hydrolysate, to a DuPont facility in New Jersey for secondary treatment and ...
openaire +1 more source