Role of microtubule dynamics in Wallerian degeneration and nerve regeneration after peripheral nerve injury [PDF]
Wallerian degeneration, the progressive disintegration of distal axons and myelin that occurs after peripheral nerve injury, is essential for creating a permissive microenvironment for nerve regeneration, and involves cytoskeletal reconstruction. However,
Jingmin Liu+16 more
doaj +4 more sources
Investigating the Association of Wallerian Degeneration and Diaschisis After Ischemic Stroke With BOLD Cerebrovascular Reactivity [PDF]
IntroductionWallerian degeneration and diaschisis are considered separate remote entities following ischemic stroke. They may, however, share common neurophysiological denominators, since they are both related to disruption of fiber tracts and brain ...
C. H. B. van Niftrik+16 more
doaj +3 more sources
Macrophage-specific RhoA knockout delays Wallerian degeneration after peripheral nerve injury in mice [PDF]
Background Plenty of macrophages are recruited to the injured nerve to play key roles in the immunoreaction and engulf the debris of degenerated axons and myelin during Wallerian degeneration, thus creating a conducive microenvironment for nerve ...
Jiawei Xu+11 more
doaj +3 more sources
Visualizing Wallerian degeneration in the corticospinal tract after sensorimotor cortex ischemia in mice [PDF]
Stroke can cause Wallerian degeneration in regions outside of the brain, particularly in the corticospinal tract. To investigate the fate of major glial cells and axons within affected areas of the corticospinal tract following stroke, we induced ...
Jiao Mu+8 more
doaj +3 more sources
Ascorbic acid accelerates Wallerian degeneration after peripheral nerve injury [PDF]
Wallerian degeneration occurs after peripheral nerve injury and provides a beneficial microenvironment for nerve regeneration. Our previous study demonstrated that ascorbic acid promotes peripheral nerve regeneration, possibly through promoting Schwann ...
Lixia Li+7 more
doaj +3 more sources
Wallerian degeneration of bilateral cerebral peduncles after acute carbon monoxide poisoning [PDF]
Background Cases of Wallerian degeneration of bilateral cerebral peduncles after acute carbon monoxide poisoning have not yet been reported. To date, most of the delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) lesions captured in ...
Sui-yi Xu+4 more
doaj +3 more sources
Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury [PDF]
Background Recovery of function from traumatic nerve injury depends on the ability of severed axons to grow/regenerate back to their target tissues. This is achieved by successfully crossing the lesion site where physical impact severed axons, determined
Gerard Elberg+5 more
doaj +3 more sources
Baculoviral inhibitor of apoptosis protein repeat-containing protein 3 delays early Wallerian degeneration after sciatic nerve injury [PDF]
Wallerian degeneration is a complex biological process that occurs after nerve injury, and involves nerve degeneration and regeneration. Schwann cells play a crucial role in the cellular and molecular events of Wallerian degeneration of the peripheral ...
Min Cai+8 more
doaj +3 more sources
Ingenuity pathway analysis of gene expression profiles in distal nerve stump following nerve injury: insights into Wallerian degeneration [PDF]
Nerve injury is a common and difficult clinical problem worldwide with a high disability rate. Different from the central nervous system, the peripheral nervous system is able to regenerate after injury.
Jun Yu, Xiaosong Gu, Sheng Yi
doaj +3 more sources
Differential gene and protein expression between rat tibial nerve and common peroneal nerve during Wallerian degeneration [PDF]
Wallerian degeneration and nerve regeneration after injury are complex processes involving many genes, proteins and cytokines. After different peripheral nerve injuries the regeneration rate can differ.
Yao-Fa Lin+4 more
doaj +3 more sources