The Gene for Slow Wallerian Degeneration (Wlds) Is Also Protective against Vincristine Neuropathy
Neurobiology of Disease, 2001 Neurological diseases are frequently associated with axonal degeneration, which leads to dysfunction though separation of neurons from their targets. The mechanisms of axonal degeneration are largely unknown and in many cases are independent of those ...
Min-Sheng Wang +3 more
doaj +2 more sources
Case report: Wallerian degeneration: The innate-immune response to adult-onset Still's disease peripheral nerve injury. [PDF]
Front Neurol, 2022 Cheng H, Lv H, Wang Y, Wang GQ.
europepmc +2 more sources
Wallerian degeneration: From mechanism to disease to imaging [PDF]
HeliyonWallerian degeneration (WD) was first discovered by Augustus Waller in 1850 in a transection of the glossopharyngeal and hypoglossal nerves in frogs. Initial studies suggested that the formation mechanism of WD is related to the nutrition of neuronal ...
Ruiqi Tian +4 more
doaj +2 more sources
Wallerian degeneration of the middle cerebellar peduncles secondary to pontine infarction, case report, and review of literature [PDF]
Radiology Case ReportsWallerian degeneration (WD) is a process of axonal degradation that occurs downstream from a primary injury site and is often seen after strokes affecting the brainstem. This case report documents WD of the bilateral middle cerebellar peduncles (MCPs) in
Zaina Brinji +3 more
doaj +2 more sources
Neutrophil peptide 1 accelerates the clearance of degenerative axons during Wallerian degeneration by activating macrophages after peripheral nerve crush injury [PDF]
Neural Regeneration ResearchMacrophages play an important role in peripheral nerve regeneration, but the specific mechanism of regeneration is still unclear. Our preliminary findings indicated that neutrophil peptide 1 is an innate immune peptide closely involved in peripheral ...
Yuhui Kou +5 more
doaj +2 more sources
Role of Cell Oxidant Status and Redox State in Controlling Cell Proliferation and Apoptosis in Two Models of Wallerian Degeneration of Rat Sciatic Nerve [PDF]
AntioxidantsAfter peripheral nerve lesion, the role of reactive oxygen species (ROS) has not been clarified during Wallerian degeneration. The present study examined the participation of oxidant stress after rat sciatic nerve injury induced by two experimental ...
Myrna Alexandra Roberta Dent +2 more
doaj +2 more sources
Signaling mechanisms regulating Wallerian degeneration [PDF]
Current Opinion in Neurobiology, 2014 Wallerian degeneration (WD) occurs after an axon is cut or crushed and entails the disintegration and clearance of the severed axon distal to the injury site. WD was initially thought to result from the passive wasting away of the distal axonal fragment, presumably because it lacked a nutrient supply from the cell body.
Marc Freeman
openaire +4 more sources
Protective effects of NAMPT or MAPK inhibitors and NaR on Wallerian degeneration of mammalian axons. [PDF]
Neurobiol Dis, 2022 Alexandris AS +9 more
europepmc +2 more sources
Clinical and magnetic resonance imaging features in acute ischemic stroke with early wallerian degeneration: a case-control study. [PDF]
BMC NeurolOta K +7 more
europepmc +3 more sources