Nogo‐A oligodendrocytes expression emerges at perilesional regions over time and suggests an extended therapeutical window for anti‐Nogo‐A pathway trageting interventrions beyond four weeks in patients after spinal cord injury. Abstract The myelin‐associated inhibitor Nogo‐A (Reticulon 4, RTN4) restricts axonal outgrowth, plasticity, and neural ...
Carmen Schwaiger+9 more
wiley +1 more source
Death Receptor 6 Promotes Wallerian Degeneration in Peripheral Axons. [PDF]
Gamage KK+8 more
europepmc +2 more sources
Wallerian degeneration in central nervous system: dynamic associations between diffusion indices and their underlying pathology. [PDF]
BACKGROUND: Although diffusion tensor imaging has been used to monitor Wallerian degeneration, the exact relationship between the evolution of diffusion indices and its underlying pathology, especially in central nervous system, remains largely unknown ...
Wen Qin+7 more
doaj +1 more source
Some identities involving degenerate Stirling numbers associated with several degenerate polynomials and numbers [PDF]
The aim of this paper is to investigate some properties, recurrence relations and identities involving degenerate Stirling numbers of both kinds associated with degenerate hyperharmonic numbers and also with degenerate Bernolli, degenerate Euler, degenerate Bell and degenerate Fubini polynomials.
arxiv +1 more source
Wallerian Degeneration, WldS, and Nmnat [PDF]
Traditionally, researchers have believed that axons are highly dependent on their cell bodies for long-term survival. However, recent studies point to the existence of axon-autonomous mechanism(s) that regulate rapid axon degeneration after axotomy.
Coleman, Michael P., Freeman, Marc R.
openaire +4 more sources
Wallerian degeneration of the corticospinal tracts [PDF]
A 35-year-old woman experienced acute onset of neck pain with dysarthria and left-sided weakness. Neurologic examination revealed a right-sided Horner’s syndrome, left facial palsy, and left hemiparesis. The diagnostic evaluation disclosed a spontaneous cervicocephalic dissection of the right internal carotid artery with infarction of the anterior ...
openaire +2 more sources
Heme Oxygenase 1 in Schwann Cells Regulates Peripheral Nerve Degeneration Against Oxidative Stress
During Wallerian degeneration, Schwann cells lose their characteristic of myelinating axons and shift into the state of developmental promyelinating cells.
Muwoong Kim+8 more
doaj +1 more source
Changes of statistical structural fluctuations unveils an early compacted degraded stage of PNS myelin [PDF]
Degradation of the myelin sheath is a common pathology underlying demyelinating neurological diseases from Multiple Sclerosis to Leukodistrophies. Although large malformations of myelin ultrastructure in the advanced stages of Wallerian degradation is known, its subtle structural variations at early stages of demyelination remains poorly characterized.
arxiv +1 more source
Bilateral Wallerian Degeneration of the Pontocerebellar Tracts [PDF]
Wallerian degeneration is the process of progressive demyelination and disintegration of the distal axonal segment following the transection of the axon or damage to the neuron. We report a case of a patient with Wallerian degeneration of the pontocerebellar tracts. She had a history of a pontine infarction 3 months ago.
Baki Hekimoglu+4 more
openaire +2 more sources
Wallerian degeneration: the innate-immune response to traumatic nerve injury
Traumatic injury to peripheral nerves results in the loss of neural functions. Recovery by regeneration depends on the cellular and molecular events of Wallerian degeneration that injury induces distal to the lesion site, the domain through which severed
Rotshenker Shlomo
doaj +1 more source