A Comprehensive Review of Interstitial Lung Abnormalities
Respirology, Volume 30, Issue 5, Page 385-397, May 2025.ABSTRACT Interstitial lung abnormalities (ILAs) represent radiological entities that comprise changes compatible with an interstitial process, occurring in individuals not suspected to have interstitial lung disease (ILD). The prevalence of ILAs ranges from 2.5% to 16.7% in lung cancer screening and population‐based cohorts. ILAs have consistently been
Yuben Moodley, John A. Mackintosh
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Evolutionary history and functional implications of protein domains and their combinations in eukaryotes [PDF]
, 2007 [Background]In higher multicellular eukaryotes, complex protein domain combinations contribute to various cellular functions such as regulation of intercellular or intracellular signaling and interactions.
Masumi Itoh +4 more
core +1 more source
Controversy and multiple roles of the solitary nucleus receptor Nur77 in disease and physiology
The FASEB Journal, Volume 39, Issue 6, 31 March 2025.Multiple roles of Nur77. Nur77 has complex biological functions, including roles in the nervous system, genome integrity, cell differentiation, cell homeostasis, oxidative stress, autophagy, aging, and infection. Furthermore, Nur77 is implicated in various neurodegenerative diseases and cancers. Abstract Neuron‐derived clone 77 (Nur77), a member of the
Yanteng Wang +3 more
wiley +1 more source
CCAAT/enhancer binding protein β directly regulates the expression of the complement component 3 gene in neural cells: implications for the pro-inflammatory effects of this transcription factor [PDF]
, 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License.[Background]: The CCAAT/enhancer-binding protein β (C/EBPβ) is a transcription factor, which was first identified as a regulator of differentiation and
Aguilar Morante, Diana +6 more
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Prodomain processing controls BMP‐10 bioactivity and targeting to fibrillin‐1 in latent conformation
The FASEB Journal, Volume 39, Issue 3, 15 February 2025.Model of BMP‐10 prodomain‐growth factor conformation and its role in controlling bioactivity. The bioactivity of BMP‐10 is regulated through conformational changes governed by intracellular or extracellular processing by proprotein convertases (PPCs).
Chara E. S. Spanou +16 more
wiley +1 more source
Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9 [PDF]
, 2013 Alcohol consumption is a known risk factor for hypertension, with recent candidate studies implicating gene-alcohol interactions in blood pressure (BP) regulation.
Kume, Rezart +4 more
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Population Proteomics: A Tool to Gain Insights Into the Inflamed Periodontium
PROTEOMICS, Volume 25, Issue 1-2, January 2025.ABSTRACT Periodontitis, characterized by inflammatory loss of tooth‐supporting tissues associated with biofilm, is among the most prevalent chronic diseases globally, affecting approximately 50% of the adult population to a moderate extent and cases of severe periodontitis surpassing the one billion mark.
Stefan Lars Reckelkamm +4 more
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Plantaricin: Production Dynamics, Functional Applications, and Challenges in Food Biopreservation
Journal of Food Processing and Preservation, Volume 2025, Issue 1, 2025.Lactiplantibacillus plantarum is a lactic acid bacterium (LAB) capable of producing antimicrobial compounds such as lactic acid, hydrogen peroxide, exopolysaccharides, and a bacteriocin known as plantaricin. Plantaricin exhibits strong inhibitory effects against both Gram‐positive and Gram‐negative pathogenic and spoilage bacteria, making it a ...
Rianti Nur Azzahra +5 more
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Comprehensive Analysis of Neonatal versus Adult Unilateral Decortication in a Mouse Model Using Behavioral, Neuroanatomical, and DNA Microarray Approaches [PDF]
, 2014 Previously, studying the development, especially of corticospinal neurons, it was concluded that the main compensatory mechanism after unilateral brain injury in rat at the neonatal stage was due in part to non-lesioned ipsilateral corticospinal neurons ...
Nakamachi Tomoya +4 more
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Artificial intelligence in rheumatoid arthritis research: A bibliometric analysis from 2004 to 2023
Rheumatology &Autoimmunity, Volume 4, Issue 3, Page 133-144, September 2024.The role of artificial intelligence in the early diagnosis and management of rheumatoid arthritis is explored in this article. Abstract Background Artificial intelligence (AI) holds promise for the screening, diagnosis, and management of patients with rheumatoid arthritis (RA).
Yang Liu +5 more
wiley +1 more source