Results 1 to 10 of about 106,451 (346)

Transcription factor ONECUT3 regulates HDAC6/HIF-1α activity to promote the Warburg effect and tumor growth in colorectal cancer [PDF]

Cell Death and Disease
The Warburg effect, also known as aerobic glycolysis, plays a crucial role in the onset and progression of colorectal cancer (CRC), although its mechanism remains unclear.
Ruixue Huo, Weihan Li, Hao Wu, Kexin He, Hao Wang, Shan Zhang, Shu-Heng Jiang, Rongkun Li, Junli Xue   +8 more
doaj   +2 more sources

Metabolic modelling links Warburg effect to collagen formation, angiogenesis and inflammation in the tumoral stroma. [PDF]

PLoS ONE
Cancer cells are known to express the Warburg effect-increased glycolysis and formation of lactic acid even in the presence of oxygen-as well as high glutamine uptake. In tumors, cancer cells are surrounded by collagen, immune cells, and neoangiogenesis.
Maxime Mahout, Laurent Schwartz, Romain Attal, Ashraf Bakkar, Sabine Peres   +4 more
doaj   +2 more sources

Fructose in the kidney: from physiology to pathology [PDF]

Kidney Research and Clinical Practice, 2021
The Warburg effect is a unique property of cancer cells, in which glycolysis is activated instead of mitochondrial respiration despite oxygen availability.
Takahiko Nakagawa, Duk-Hee Kang
doaj   +1 more source

Evolutionary dynamics of the Warburg effect: Glycolysis as a collective action problem among cancer cells. [PDF]

, 2013
Archetti, Marco
core   +3 more sources

Warburg effect‐related risk scoring model to assess clinical significance and immunity characteristics of glioblastoma

Cancer Medicine, 2023
Background Glioblastoma (GBM), the most common primary malignant brain tumor, has a poor prognosis, with a median survival of only 14.6 months.
Rong Zhang, Can Wang, Xiaohong Zheng, Shenglan Li, Weichunbai Zhang, Zhuang Kang, Shuo Yin, Jinyi Chen, Feng Chen, Wenbin Li   +9 more
doaj   +1 more source

Research Progress on Regulatory Mechanism of Ubiquitin Modification on Warburg Effect in Malignant Tumors

Zhongliu Fangzhi Yanjiu, 2022
Ubiquitin modification and Warburg effect play an important role in the occurrence and development of tumors. The process of tumor ubiquitin modification is closely related to glycolysis, that is, ubiquitin modification in tumor cells can regulate the ...
WANG Fengli, HU Jing
doaj   +1 more source

Human tau promotes Warburg effect-like glycolytic metabolism under acute hyperglycemia conditions. [PDF]

J Biol Chem
Yao J, Li K, Fu Z, Zheng J, Chen Z, Xu J, Lai G, Huang Y, Huang J, You G, Han S, He Z, Liu Q, Li N.   +13 more
europepmc   +2 more sources

The HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer:Targets for Effective Therapy with 3-Bromopyruvate [PDF]

, 2016
This review summarizes the current state of knowledge about the metabolism of cancer cells, especially with respect to the “Warburg” and “Crabtree” effects.
Andre Goffeau, Arora, Bustamante, Dell’Antone, Dyląg, Forman, Gandham, Hinson, Icard, Kaplan, Katarzyna Niedźwiecka, Kennedy, Lehninger, Lis, Lu, Mariusz Dyląg, Meister, Nakashima, Nakashima, Patrick, Paweł Lis, Pedersen, Pedersen, Peter Pedersen, Ramos, Stanisław Ułaszewski, Van Urk, Vora, Weber, Young Ko, Zhang, Zhang, Zhang   +32 more
core   +7 more sources

Warburg effect in colorectal cancer: the emerging roles in tumor microenvironment and therapeutic implications

Journal of Hematology & Oncology, 2022
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related death worldwide. Countless CRC patients undergo disease progression.
Xinyang Zhong, Xuefeng He, Yaxian Wang, Zijuan Hu, Huixia Huang, Senlin Zhao, Ping Wei, Dawei Li   +7 more
doaj   +1 more source

Hydrogen Sulfide Ameliorates Angiotensin II-Induced Atrial Fibrosis Progression to Atrial Fibrillation Through Inhibition of the Warburg Effect and Endoplasmic Reticulum Stress

Frontiers in Pharmacology, 2021
Atrial fibrosis is the basis for the occurrence and development of atrial fibrillation (AF) and is closely related to the Warburg effect, endoplasmic reticulum stress (ERS) and mitochondrion dysfunctions-induced cardiomyocyte apoptosis. Hydrogen sulfide (
Heng-Jing Hu, Heng-Jing Hu, Xiu-Heng Wang, Yao Liu, Tian-Qing Zhang, Zheng-Rong Chen, Chi Zhang, Zhi-Han Tang, Shun-Lin Qu, Hui-Fang Tang, Zhi-Sheng Jiang, Zhi-Sheng Jiang, Zhi-Sheng Jiang   +12 more
doaj   +1 more source