Results 1 to 10 of about 678,174 (319)
Synaptic Plasticity and the Warburg Effect [PDF]
Cell Metabolism, 2014 Functional brain imaging studies show that in certain brain regions glucose utilization exceeds oxygen consumption, indicating the predominance of aerobic glycolysis. In this issue, Goyal et al. (2014) report that this metabolic profile is associated with an enrichment in the expression of genes involved in synaptic plasticity and remodeling processes.
Pierre J. Magistretti +2 more
openaire +7 more sources
Partners in the Warburg effect [PDF]
eLife, 2016 Cells that surround tumors produce vesicles that supply nutrients to cancer cells and, more surprisingly, also impair the generation of energy in these cancer cells.
Joshua D Rabinowitz, Hilary A Coller
doaj +4 more sources
Fructose in the kidney: from physiology to pathology [PDF]
Kidney Research and Clinical Practice, 2021 The Warburg effect is a unique property of cancer cells, in which glycolysis is activated instead of mitochondrial respiration despite oxygen availability.
Takahiko Nakagawa, Duk-Hee Kang
doaj +1 more source
Cancer Medicine, 2023 Background Glioblastoma (GBM), the most common primary malignant brain tumor, has a poor prognosis, with a median survival of only 14.6 months.
Rong Zhang +9 more
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2022 Ubiquitin modification and Warburg effect play an important role in the occurrence and development of tumors. The process of tumor ubiquitin modification is closely related to glycolysis, that is, ubiquitin modification in tumor cells can regulate the ...
WANG Fengli, HU Jing
doaj +1 more source
Autophagy, Warburg, and Warburg Reverse Effects in Human Cancer [PDF]
BioMed Research International, 2014 Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanisms to a nonoxidative breakdown of ...
González, Claudio Daniel +5 more
openaire +3 more sources
Journal of Hematology & Oncology, 2022 Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related death worldwide. Countless CRC patients undergo disease progression.
Xinyang Zhong +7 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Atrial fibrosis is the basis for the occurrence and development of atrial fibrillation (AF) and is closely related to the Warburg effect, endoplasmic reticulum stress (ERS) and mitochondrion dysfunctions-induced cardiomyocyte apoptosis. Hydrogen sulfide (
Heng-Jing Hu +12 more
doaj +1 more source
The Warburg effect: 80 years on [PDF]
Biochemical Society Transactions, 2016 Influential research by Warburg and Cori in the 1920s ignited interest in how cancer cells' energy generation is different from that of normal cells. They observed high glucose consumption and large amounts of lactate excretion from cancer cells compared with normal cells, which oxidised glucose using mitochondria.
Morten, K, Potter, M, Newport, E
openaire +4 more sources
Expression of proteins associated with the Warburg‐effect and survival in colorectal cancer
The Journal of Pathology: Clinical Research, 2022 Previous research has suggested that the expression of proteins related to the Warburg effect may have prognostic value in colorectal cancer (CRC), but results remain inconsistent.
Kelly Offermans +9 more
doaj +1 more source