Results 11 to 20 of about 13,460,861 (391)
Partners in the Warburg effect [PDF]
eLife, 2016 Cells that surround tumors produce vesicles that supply nutrients to cancer cells and, more surprisingly, also impair the generation of energy in these cancer cells.
Joshua D Rabinowitz, Hilary A Coller
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Revisiting the Warburg Effect with Focus on Lactate
Cancers, 2022 Simple Summary Almost a century ago, Nobel Prize laureate Otto Warburg realized that cancer cells consumed much more glucose than normal cells and also produced large amounts of lactate even in aerobic conditions, which was very surprising at the time ...
E. Kociánová +2 more
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Nuclear Receptors and the Warburg effect in cancer [PDF]
International Journal of Cancer, 2015 In 1927 Otto Warburg established that tumours derive energy primarily from the conversion of glucose to lactic acid and only partially through cellular respiration involving oxygen.
Abedin SA +15 more
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The epigenetic basis of the Warburg effect [PDF]
Epigenetics, 2010 Cancer development results from the accumulation of genetic and epigenetic changes. By interacting with intracellular signaling to promote carcinogenesis, epigenetic networks can actively transform cancer-promoting signals from tumor-permissive microenvironment to coordinate cellular proliferation and metabolism in the initiation and progression of ...
Xian Wang, Hongchuan Jin
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Fructose in the kidney: from physiology to pathology [PDF]
Kidney Research and Clinical Practice, 2021 The Warburg effect is a unique property of cancer cells, in which glycolysis is activated instead of mitochondrial respiration despite oxygen availability.
Takahiko Nakagawa, Duk-Hee Kang
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The Warburg effect: a signature of mitochondrial overload.
Trends in Cell Biology, 2023 A long-standing question in cancer biology has been why oxygenated tumors ferment the majority of glucose they consume to lactate rather than oxidizing it in their mitochondria, a phenomenon known as the 'Warburg effect.' An abundance of evidence shows not only that most cancer cells have fully functional mitochondria but also that mitochondrial ...
Yahui Wang, Gary J. Patti
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Zhongliu Fangzhi Yanjiu, 2022 Ubiquitin modification and Warburg effect play an important role in the occurrence and development of tumors. The process of tumor ubiquitin modification is closely related to glycolysis, that is, ubiquitin modification in tumor cells can regulate the ...
WANG Fengli, HU Jing
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The Warburg effect: a score for many instruments in the concert of cancer and cancer niche cells
Pharmacological Reports, 2023 Although Warburg's discovery of intensive glucose uptake by tumors, followed by lactate fermentation in oxygen presence of oxygen was made a century ago, it is still an area of intense research and development of new hypotheses that, layer by layer ...
Martyna Jaworska +6 more
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Autophagy, Warburg, and Warburg Reverse Effects in Human Cancer [PDF]
BioMed Research International, 2014 Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanisms to a nonoxidative breakdown of ...
González, Claudio Daniel +5 more
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International Journal of Molecular Sciences, 2023 The Warburg effect is the long-standing riddle of cancer biology. How does aerobic glycolysis, inefficient in producing ATP, confer a growth advantage to cancer cells? A new evaluation of a large set of literature findings covering the Warburg effect and
Lilia Alberghina
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