Results 41 to 50 of about 108,453 (351)
Relevance of the Warburg Effect in Tuberculosis for Host-Directed Therapy
Frontiers in Cellular and Infection Microbiology, 2020 Tuberculosis (TB) was responsible for more deaths in 2019 than any other infectious agent. This epidemic is exacerbated by the ongoing development of multi-drug resistance and HIV co-infection.
Bridgette M. Cumming +4 more
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Scientific Reports, 2023 Proliferative diabetic retinopathy (PDR) remains a leading cause of blindness despite progress in screening and treatment. Recently, the Warburg effect, a metabolic alteration affecting amino acid (AA) metabolism in proliferating cells, has drawn ...
Andrew Gregory +7 more
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Hepatocellular carcinoma: Review of disease and tumor biomarkers. [PDF]
, 2016 © The Author(s) 2016.Hepatocellular carcinoma (HCC) is a common malignancy and now the second commonest global cause of cancer death. HCC tumorigenesis is relatively silent and patients experience late symptomatic presentation. As the option for curative
Cox, IJ +8 more
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Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect
Frontiers in Cell and Developmental Biology, 2018 The Warburg Effect, or aerobic glycolysis, is one of the major metabolic alterations observed in cancer. Hypothesized to increase a cell's proliferative capacity via regenerating NAD+, increasing the pool of glycolytic biosynthetic intermediates, and ...
Elizabeth K. Wiese +3 more
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Molecular Medicine, 2023 Background The main cause of high mortality from sepsis is that immunosuppression leads to life-threatening organ dysfunction, and reversing immunosuppression is key to sepsis treatment. Interferon γ (IFNγ) is a potential therapy for immunosuppression of
Xu-zhe Fu, Yu Wang
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Mechanisms Governing Metabolic Heterogeneity in Breast Cancer and Other Tumors
Frontiers in Oncology, 2021 Reprogramming of metabolic priorities promotes tumor progression. Our understanding of the Warburg effect, based on studies of cultured cancer cells, has evolved to a more complex understanding of tumor metabolism within an ecosystem that provides and ...
Sayani Patra +19 more
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Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle [PDF]
, 2015 Cancer cells utilize large amounts of ATP to sustain growth, relying primarily on non-oxidative, fermentative pathways for its production.
CAPUANI, FABRIZIO +3 more
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Oxygen Transfer on Substituted ZrO2, Bi2O3, and CeO2 Electrolytes with Platinum Electrodes II. A-C Impedance Study [PDF]
, 1983 An equivalent electrical circuit that describes the electrode processes on different electrolytes, using porous Pt electrodes,is given. Diffusional processes are important and have to be presented by Warburg components in the circuit.
Burggraaf, A.J., Verkerk, M.J.
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Warburg′s effect on solid tumors
Saudi Journal of Kidney Diseases and Transplantation, 2014 Lactic acidosis is the result of imbalance between the systemic formation of lactate and its hepatic metabolism. In cancer patients, lactic acidosis is mainly associated with hematologic malignancies (leukemia and lymphomas) and the mechanism is known as Warburg's effect.
Talal El Imad +2 more
openaire +3 more sources
Biology, 2021 Colorectal cancer (CRC) development is a gradual process defined by the accumulation of numerous genetic mutations and epigenetic alterations leading to the adenoma-carcinoma sequence.
Batoul Abi Zamer +4 more
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