Results 41 to 50 of about 47,258 (264)

Correlation between the Warburg effect and progression of triple-negative breast cancer

open access: yesFrontiers in Oncology, 2023
Triple-negative breast cancer (TNBC) is ineligible for hormonal therapy and Her-2-targeted therapy due to the negative expression of the estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2. Although targeted therapy and
Shaojun Liu   +4 more
doaj   +1 more source

Laser‐Induced Graphene from Waste Almond Shells

open access: yesAdvanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova   +9 more
wiley   +1 more source

Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer

open access: yesActa Pharmaceutica Sinica B
Cancer reprogramming is an important facilitator of cancer development and survival, with tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation, even under sufficient oxygen supply condition.
Minru Liao   +6 more
doaj   +1 more source

An invertebrate Warburg effect: a shrimp virus achieves successful replication by altering the host metabolome via the PI3K-Akt-mTOR pathway.

open access: yesPLoS Pathogens, 2014
In this study, we used a systems biology approach to investigate changes in the proteome and metabolome of shrimp hemocytes infected by the invertebrate virus WSSV (white spot syndrome virus) at the viral genome replication stage (12 hpi) and the late ...
Mei-An Su   +15 more
doaj   +1 more source

Synergistic Induction of Potential Warburg Effect in Zebrafish Hepatocellular Carcinoma by Co-Transgenic Expression of Myc and xmrk Oncogenes. [PDF]

open access: yesPLoS ONE, 2015
Previously we have generated inducible liver tumor models by transgenic expression of Myc or xmrk (activated EGFR homolog) oncogenes in zebrafish. To investigate the interaction of the two oncogenes, we crossed the two transgenic lines and observed more ...
Zhen Li   +4 more
doaj   +1 more source

mTORC2 dictates Warburg effect and drug resistance [PDF]

open access: yesCell Cycle, 2014
Metabolic reprogramming, a prominent phenotype in cancer cells, is the adaptation to shifts in the usage of metabolites, including glucose, fatty acids, amino acids, and glutamine. The central feature of this adaptation lies in the fact that cancer cells undergo glycolysis even in the presence of ample oxygen, contrary to normal cells.1 This aerobic ...
Masui, Kenta   +2 more
openaire   +2 more sources

PTFE‐Activated Graphene Overcomes Dispersion Challenges for Scalable Solvent‐Free Fabrication of Ultra‐Thick, High‐Performance Cathodes in Lithium Metal Batteries

open access: yesAdvanced Functional Materials, EarlyView.
PTFE nanoparticle–anchored rGO (rGO@PTFE) for scalable solvent‐free fabrication of ultra‐thick, high‐density cathodes, achieving high conductivity (9.55 S cm−1), lithium transference (0.73), and improved wettability, is developed. The resulting cathode delivers 15.2 mAh cm−2 areal and 563 mAh cm−3 volumetric capacities, with full cells exhibiting 637 ...
Juhee Yoon   +7 more
wiley   +1 more source

Synaptic Plasticity and the Warburg Effect [PDF]

open access: yesCell Metabolism, 2014
Functional brain imaging studies show that in certain brain regions glucose utilization exceeds oxygen consumption, indicating the predominance of aerobic glycolysis. In this issue, Goyal et al. (2014) report that this metabolic profile is associated with an enrichment in the expression of genes involved in synaptic plasticity and remodeling processes.
openaire   +3 more sources

Warburg effect hypothesis in autism Spectrum disorders [PDF]

open access: yesMolecular Brain, 2018
Autism spectrum disorder (ASD) is a neurodevelopmental disease which is characterized by a deficit in social interactions and communication with repetitive and restrictive behavior. In altered cells, metabolic enzymes are modified by the dysregulation of the canonical WNT/β-catenin pathway. In ASD, the canonical WNT/β-catenin pathway is upregulated. We
Alexandre Vallée, Jean-Noël Vallée
openaire   +3 more sources

Artificial Amorphous Interface Matters for Boosting High‐Voltage Stable LiCoO2 Cathode

open access: yesAdvanced Functional Materials, EarlyView.
The amorphization of phosphate‐based surface layer with favorable Li‐ion conducting kinetics is realized by precisely tailored atomic‐level fabrication. This amorphous coating enables the lithium cobalt oxide (LCO) cathode superior high‐voltage rate capability and cycling performance, owing to the fast interfacial ionic transport and maintained ...
Jinjin Ma   +10 more
wiley   +1 more source

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