Results 81 to 90 of about 106,451 (346)

Anti-Warburg effect of rosmarinic acid via miR-155 in gastric cancer cells

open access: yesDrug Design, Development and Therapy, 2015
Shuai Han,* Shaohua Yang,* Zhai Cai, Dongyue Pan, Zhou Li, Zonghai Huang, Pusheng Zhang, Huijuan Zhu, Lijun Lei, Weiwei Wang Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of China ...
Han S   +9 more
doaj  

Hippocampal warburg effect mediates hydrogen sulfide-ameliorated diabetes-associated cognitive dysfunction: Involving promotion of hippocampal synaptic plasticity

open access: yesNeuroscience Research
Our previous studies have reported that hydrogen sulfide (H2S) has ability to improve diabetes-associated cognitive dysfunction (DACD), but the exact mechanisms remain unknown.
Run-Qi Li   +7 more
doaj   +1 more source

Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition

open access: yesScientific Reports, 2018
Warburg effect is an emerging hallmark of cancer cells with pyruvate kinase M2 (PKM2) as its key regulator. Curcumin is an extensively-studied anti-cancer compound, however, its role in affecting cancer metabolism remains poorly understood.
Farid Ahmad Siddiqui   +11 more
doaj   +1 more source

Emerging role of the pentose phosphate pathway in hepatocellular carcinoma [PDF]

open access: yes, 2017
In recent years, there has been a revival of interest in metabolic changes of cancer cells as it has been noticed that malignant transformation and metabolic reprogramming are closely intertwined.
Columbano, Amedeo   +2 more
core   +2 more sources

Genetic analysis of the Warburg effect in yeast [PDF]

open access: yesAdvances in Biological Regulation, 2015
We recently discovered that the Warburg effect, defined by the dramatically enhanced metabolism of glucose to pyruvate, even in well-oxygenated cancer cells, can occur as a consequence of mutations that enhance lipid biosynthesis at the expense of respiratory capacity.
Bola, Olayanju   +2 more
openaire   +2 more sources

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

open access: yesAdvanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han   +17 more
wiley   +1 more source

Metformin as a Therapeutic Target in Endometrial Cancers. [PDF]

open access: yes, 2018
Endometrial cancer is the most common gynecologic malignancy in developed countries. Its increasing incidence is thought to be related in part to the rise of metabolic syndrome, which has been shown to be a risk factor for the development of ...
Johnson, Jennifer   +6 more
core   +2 more sources

Differentiating the Synergistic Interactions Between Li+ Salts and Cyclic to Linear Carbonate Ratios to Enable Wide‐Temperature Performance of Lithium‐Ion Batteries

open access: yesAdvanced Functional Materials, EarlyView.
The coordination in carbonate solvents and degradation products of lithium difluoro(oxolato) borate (LiDFOB) salt enables sufficient passivation of both LiNi0.8Mn0.1Co0.1O2 (NMC811) cathode and graphite anode in the absence of ethylene carbonate (EC).
Thomas J. Watts   +2 more
wiley   +1 more source

Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

open access: yes, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz   +431 more
core   +2 more sources

Enhanced Mechanical and Electrochemical Properties of Carbon Nanotube Fibers via Embedded Sucrose‐Derived Porous Carbon for Mechanoelectrochemical Energy Harvesting

open access: yesAdvanced Functional Materials, EarlyView.
Sucrose‐derived porous carbon network (SPINE‐C) is formed within CNT fibers via FCCVD, bridging inter‐bundles of CNTs and increasing surface area through introduced microporosity. As a result, both mechanical and electrochemical properties are simultaneously enhanced, leading to a 2.8‐fold increase in the power density of a mechano‐electrochemical ...
Hocheol Gwac   +9 more
wiley   +1 more source

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