Results 61 to 70 of about 2,466,381 (317)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Optical clearing and shielding with fan-shaped vortex beams

APL Photonics, 2020
We propose and demonstrate a new method for creation of fan-shaped optical vortex beams by rational phase modulation and assembly based on a well-known conical vortex phase.
Haiping Wang, Liqin Tang, Jina Ma, Huiwen Hao, Xiuyan Zheng, Daohong Song, Yi Hu, Yigang Li, Zhigang Chen   +8 more
doaj   +1 more source

Introduction to Weak Measurements and Weak Values

Quanta, 2013
We present a short review of the theory of weak measurement. This should serve as a map for the theory and an easy way to get familiar with the main results, problems and paradoxes raised by the theory. Quanta 2013; 2: 7–17.
Boaz Tamir, Eliahu Cohen
openaire   +3 more sources

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

A weak turbulence theory for incompressible magnetohydrodynamics [PDF]

, 2000
We derive a weak turbulence formalism for incompressible magnetohydrodynamics. Three-wave interactions lead to a system of kinetic equations for the spectral densities of energy and helicity. The kinetic equations conserve energy in all wavevector planes
S. V. Nazarenko, Nazarenko, Sergey, S. Galtier, Galtier, S., Newell, Alan C., Pouquet, A., A. C. Newell, A. Pouquet   +7 more
core   +1 more source

Weak-Key Analysis for BIKE Post-Quantum Key Encapsulation Mechanism

, 2023
Weak-Key Analysis for BIKE Post-Quantum Key Encapsulation ...
Syed Wajid Ali Shah (13096779), Ashish Nanda (13059273), Robin Ram Mohan Doss (13090617), Mohammad Nosouhi (13087743), Lei Pan (13101435), P Gauravaram (16064735), Y Zolotavkin (14451261)   +6 more
core   +1 more source

Topological Evolution and Nonconservation of Fractional Vector Optical Fields in Linear and Nonlinear Regimes

Photonics
The topological properties of vector optical fields are traditionally considered strictly conserved during continuous deformations and linear propagation.
Jiahao Zhao, Xizhe Hou, Yue Li, Xuan Zhang, Yongnan Li, Chenghou Tu   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The integrated angular bispectrum of weak lensing [PDF]

, 2022
openWe investigate three-point statistics in weak lensing convergence, through the integrated angular bispectrum. It involves measuring the three-point function of harmonic multipoles of the lensing field by estimating how the angular power spectrum (two-
REBESCHINI, LEONARDO
core