Results 41 to 50 of about 847,820 (230)

Inhibition of oncogenic transcription factor REL by the natural product derivative calafianin monomer 101 induces proliferation arrest and apoptosis in human B-lymphoma cell lines [PDF]

open access: yes, 2015
Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB.
Chennamadhavuni, Spandan   +4 more
core   +2 more sources

Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells [PDF]

open access: yes, 2018
Estrogen receptor α (ERα) is expressed in tissues as diverse as brains and mammary glands. In breast cancer, ERα is a key regulator of tumor progression.
Acconcia   +111 more
core   +2 more sources

Induction of Extracellular Matrix Glycoproteins in Brassica Petioles by Wounding and in Response to Xanthomonas campestris

open access: yesMolecular Plant-Microbe Interactions, 1997
A panel of monoclonal antibodies that recognize plant extracellular matrix glycoproteins previously implicated in plant-microbe interactions was used to study the effects of pathogen inoculation and wounding on glycoproteins in petioles of Brassica ...
Huw A. Davies   +2 more
doaj   +1 more source

Recombinant antigens for immunodiagnosis of cystic echinococcosis

open access: yesBiological Procedures Online, 2004
Three cDNAs, termed EpC1, TPxEg and EgG5, were isolated by immunoscreening from an Echinococcus granulosus cDNA library. The recombinant phages exhibited strong reactivity with sera from humans with confirmed cystic echinococcosis (CE) and with sera from
Li Jun, Zhang Wen-Bao, McManus Donald P.
doaj   +1 more source

Western Blot diagnostic yield for simultaneous antibody detection in patients with human cysticercosis, hydatidosis, and human fascioliasis

open access: yesRevista Peruana de Medicina Experimental y Salud Pública, 2016
Objectives. To determine the diagnostic yield using western blotting to simultaneously detect antibodies in patients with human cysticercosis, hydatidosis, and human fascioliasis. Materials and methods.
Kelly Davelois   +2 more
doaj   +1 more source

Development and evaluation of an indirect ELISA for detection of Teladorsagia circumcincta infection in sheep

open access: yesBMC Veterinary Research, 2021
Background The gastrointestinal helminth, Teladorsagia circumcincta, is one of the major health risks and production-limiting diseases in small ruminant populations, particularly in temperate regions.
Jalal Aliabadi   +2 more
doaj   +1 more source

A Novel Western Multi-blotting Device [PDF]

open access: yes, 2012
poster abstractBlotting is a common technique widely used for molecular analysis in life sciences. The Western blot, in particular, is a process of transferring protein samples from a polyacrylamide gel to a blotting membrane and detecting the levels of ...
Blair, Matthew   +3 more
core  

New histone deacetylase inhibitors as potential therapeutic tools for advanced prostate carcinoma [PDF]

open access: yes, 2008
The anti-epileptic drug valproic acid is also under trial as an anti-cancer agent due to its histone deacetylase (HDAC) inhibitory properties. However, the effects of valproic acid (VPA) are limited and concentrations required for exerting anti ...
Atmaca, Akin   +8 more
core   +1 more source

InterAKTions with FKBPs - mutational and pharmacological exploration [PDF]

open access: yes, 2013
The FK506-binding protein 51 (FKBP51) is an Hsp90-associated co-chaperone which regulates steroid receptors and kinases. In pancreatic cancer cell lines, FKBP51 was shown to recruit the phosphatase PHLPP to facilitate dephosphorylation of the kinase Akt,
Biondi, Ricardo M.   +5 more
core   +6 more sources

The evolutionary rewiring of ubiquitination targets has reprogrammed the regulation of carbon assimilation in the pathogenic yeast Candida albicans [PDF]

open access: yes, 2012
Date of Acceptance: 13/11/2012 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in ...
Ashe   +78 more
core   +1 more source

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