Effects of Uniaxial Cyclic Strain on Endothelial Progenitor Cells [PDF]
Despite the high prevalence of calcific aortic valve disease (CAVD), the underlying mechanisms of pathogenesis have not been found yet. Therefore, it is extremely important to study CAVD and understand how it develops.
Zeballos Castro, Maria Alejandra
core +2 more sources
The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability [PDF]
USP21 is a centrosome-associated deubiquitylase (DUB) that has been implicated in the formation of primary cilia - crucial organelles for the regulation of the Hedgehog (Hh) signaling pathway in vertebrates. Here, we identify KCTD6 - a cullin-3 E3-ligase
Bertsoulaki, Erithelgi +6 more
core +1 more source
Phosphorylation of MCPH1 isoforms during mitosis followed by isoform‐specific degradation by APC/C‐CDH1 [PDF]
Microcephalin‐1 (MCPH1) exists as 2 isoforms that regulate cyclin‐dependent kinase‐1 activation and chromosome condensation during mitosis, with MCPH1 mutations causing primary microcephaly.
Blain, Peter G. +5 more
core +2 more sources
The protein antigens secreted in vivo by adult male Schistosoma mansoni [PDF]
Adult schistosomes can be transferred surgically from donor C57BL/6 mice to the portal veins of naive recipients with complete success. This procedure bypasses larval development and the antibody response of the host is directed against, and can be used ...
Cutts, L., Wilson, R.A.
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Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo. [PDF]
We have developed affinity chromatography methods for the isolation of microtubule-associated proteins (MAPs) from soluble cytoplasmic extracts and have used them to analyze the cytoskeleton of the early Drosophila embryo.
Alberts, BM, Field, CM, Kellogg, DR
core
A Molecular Basis for Stabilization of the von Hippel-Lindau (VHL) Tumor Suppressor Protein by Components of the VHL Ubiquitin Ligase [PDF]
The multiprotein von Hippel-Lindau (VHL) tumor suppressor (CBCVHL, Cul2-Elongin BC-VHL) and SCF (Skp1-Cul1/Cdc53-F-box protein) complexes are members of structurally related families of E3 ubiquitin ligases that use a heterodimeric module composed of a ...
Brower, Christopher S. +3 more
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A simple, flexible, and high‐efficiency western blot analysis for age‐related human induced neurons [PDF]
Yanfei Shen +4 more
openalex +1 more source
Análisis de la expresión transgénica en plantas, mediante la técnica Western Blotting
La transformación de plantas mediante la tecnología del DNA recombinante es un proceso cuyo resultado debe evaluarse a nivel molecular aplicando técnicas de análisis de la expresión transgénica.
Leidy Andrea Ávila Sánchez +1 more
doaj
The mitochondrial cytochrome c oxidase, the terminal enzyme of the respiratory chain, contains heme and copper centers for electron transfer. The conserved COX2 subunit contains the CuA site, a binuclear copper center.
Aich, A. +11 more
core +2 more sources
Specific and versatile monoclonal antibodies for hantavirus research
Rodent-borne hantaviruses pose a continual public health threat to humans through zoonotic transmission, with case fatality rates of up to 50% in some cases.
Autumn LaPointe +5 more
doaj +1 more source

