Разработка и регистрация лекарственных средств, 2021 Introduction. The stage of wet granulation is often used in the technology of solids. The method of wet granulation in a mixer-granulator with high shear force can be regarded as the most complicated method of its implementation from the engineering and ...
O. N. Abrosimova, M. A. Burakova
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Effect of operating conditions and physico–chemical properties on the wet granulation kinetics in high shear mixer [PDF]
, 2009 The wet granulation process is sensitive to changes in product properties and process variables. The optimal process and formulation are based on the knowledge of the granule growth mechanisms and of the effects of product properties and process ...
Benali, Mohammed +2 more
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Influence of process variables on the properties of simvastatin self-emulsifying granules obtained through high shear wet granulation [PDF]
, 2015 Improvements of the oral bioavailability of lipophilic drugs can be obtained using lipidic formulations such as the self-emulsifying drug delivery systems.
Benda L. +5 more
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High-Speed Tableting of High Drug-Loaded Tablets Prepared from Fluid-Bed Granulated Isoniazid
Pharmaceutics, 2023 The aim of this feasibility study was to investigate the possibility of producing industrial-scale relevant, robust, high drug-loaded (90.9%, w/w) 100 mg dose immediate-release tablets of isoniazid and simultaneously meet the biowaiver requirements. With
Valentyn Mohylyuk, Dace Bandere
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Modelling the Effect of Process Parameters on the Wet Extrusion and Spheronisation of High-Loaded Nicotinamide Pellets Using a Quality by Design Approach [PDF]
, 2019 Open access articleThe aim of the present study was to develop an alternative process to spray granulation in order to prepare high loaded spherical nicotinamide (NAM) pellets by wet extrusion and spheronisation.
Keppler, Julia K +4 more
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Predicting pharmaceutical particle size distributions using kernel mean embedding [PDF]
, 2020 In the pharmaceutical industry, the transition to continuous manufacturing of solid dosage forms is adopted by more and more companies. For these continuous processes, high-quality process models are needed.
De Beer, Thomas +3 more
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PREPARATION AND EVALUATION OF SUSTAINED-RELEASE DICLOFENAC SODIUM TABLETS
Zagazig Journal of Pharmaceutical Sciences, 2008 The aim of this work is to prepare and evaluate sustained-release matrix diclofenac sodium (DS) tablets using simple diluents by either direct compression or wet granulation techniques. The prepared tablets were evaluated for physical characteristics and
Hussein Sayed +2 more
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Development of nutraceutical product [PDF]
, 2015 The aim of this study was to discuss the development of nutraceutical product which includes the current market trends, challenges, and exploitation of natural resources through various processing.
Chin, Nyuk Ling +2 more
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Comprehensive review on modern techniques of granulation in pharmaceutical solid dosage forms
Intelligent PharmacyThis comprehensive review explores modern granulation techniques in pharmaceutical dosage forms along with conventional methods, focusing on dry granulation and wet granulation.
Anil Kumar Vadaga +4 more
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Formulation and evaluation of theophylline sustained release matrix tablets using synthetic polymers
Journal of Applied Pharmaceutical Research, 2022 The aim of present work was to develop theophylline sustained release tablets which could improve patient compliance towards the effective management of asthma The polymers, HPMC (Hydroxy propyl methyl cellulose) K4M, HPMC K100M, Eudragit, Chitosan in ...
Navdeep Kaur, Mohit Kumar
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