Results 111 to 120 of about 45,444 (316)

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

Flavour and Fragrance Journal, EarlyView.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan, Yuhan Dong, Zishuo Guo, Xiaodong Zhao, Jian Liu, Fangyuan Zhu, Shengjie Ge, Chengcheng Liu, Shuai Xu, Ming Xia   +9 more
wiley   +1 more source

Identification of Immune-Related Genes as Biomarkers for Uremia

International Journal of General Medicine, 2023
Dongning Lyu, Guangyu He, Kan Zhou, Jin Xu, Haifei Zeng, Tongyu Li, Ningbo Tang Department of Nephrology Clinic, Guangxi International Zhuang Medicine Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, Guangxi, People’s Republic of ...
Lyu D, He G, Zhou K, Xu J, Zeng H, Li T, Tang N   +6 more
doaj  

Transcriptome and WGCNA reveal hub genes in sugarcane tiller seedlings in response to drought stress [PDF]

, 2023
Yuwei Tang, Jiahui Li, Qiqi Song, Cheng Qin, Qinliang Tan, Quanguang Zhou, Zemei Nong, Ping Lv   +7 more
openalex   +1 more source

Microbial influences on immune modulation and colorectal cancer progression through combined transcriptomic and microbiomic analysis

iMetaOmics, EarlyView.
Schematic representation of the distinct tumor microenvironment characteristics in CA1 and CA2 subtypes. CA1 illustrates an immune‐active tumor microenvironment characterized by elevated infiltration of immune cells, particularly CD8 + T cells and macrophages, and enhanced IFN‐γ signaling.
Shuting Xia, Likun Wang, Yangzhuo Xu, Jiaqi Zhang, Zeyang Zhou, Libing Sun, Heng Li, Chungen Xing, Jialu Mao, Yina Liu, Fulin Yang, Ling Zhong, Jiancheng Xu, Xiaodong Yang, Zhemin Zhou   +14 more
wiley   +1 more source

Coexpression network analysis of platelet genes in sickle cell disease

Platelets, 2019
Platelets play important roles in vascular health. Activation of platelet may contribute to coagulation and inflammation. Evidence suggests circulating platelets are chronically activated in sickle cell disease (SCD) patients with steady state and ...
Fang-Fang Liu, Tong-Tao Tu, Hong-Feng Zhang, Fan Hu, Liang Huang, Lin-Feng Deng, Mao Guo, Qing Wei, Ke Li   +8 more
doaj   +1 more source

Majorbio Cloud 2026 provides comprehensive analysis workflows for microbiome

iMeta, EarlyView.
The integrated microbiome data analysis platform on Majorbio Cloud (https://cloud.majorbio.com/) encompasses 26 analytical workflows, with a core architecture of two modules: single‐omics workflows and cross‐omics integration and correlation workflows.
Jianhua Zhao, Linmeng Liu, Jichen Han, Junbiao Zhang, Xiaodan Li, Yan Wang, Qianhui Han, Xue Gong, Linna Zhang, Hao Gao, Bing Yang, Yachen Dong, Huasheng Huang, Xianglin Zhang, Kegang Yu   +14 more
wiley   +1 more source

Identification of Potential Drug Targets for the Treatment of Severe Burn Wounds from a Multi-Omics Perspective

Journal of Inflammation Research
Gehua Zhu,1,* Jiaqi Li,2,* Jiamin Xu,1 Guanghua Guo,1 Feng Zhu2 1Medical Centre of Burn Plastic and Wound Repair, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, People’s Republic of China; 2Department of ...
Zhu G, Li J, Xu J, Guo G, Zhu F
doaj  

Integrated PPI- and WGCNA-retrieval of hub gene signatures for soft substrates inhibition of human fibroblasts proliferation and differentiation [PDF]

, 2022
Ziran Xu, Tian Zhou, Yin Wang, Leijie Zhu, Jihao Tu, Zhixiang Xu, Lisha Li, Yulin Li   +7 more
openalex   +1 more source

PD‐1/PD‐L1 in Hepatocellular Carcinoma (2014–2024): A Combined Macro and Micro Analysis of Immunotherapy Implications

iNew Medicine, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) represents a significant global health issue, with the PD‐1/PD‐L1 axis serving a pivotal target for immunotherapy in this malignancy. However, a comprehensive bibliometric analysis of PD‐1/PD‐L1 research in HCC is lacking.
Xingyu Zhu, Lin Tang, Hongyan Li, Hao Li, Jiamei Wang   +4 more
wiley   +1 more source

Screening of m6A-associated ferroptosis-related genes in atherosclerosis based on WGCNA

Frontiers in Cardiovascular Medicine
BackgroundN6-methyladenosine (m6A) has been shown to mediate ferroptosis but its role in atherosclerosis (AS) is unclear.MethodsDifferentially expressed m6A-associated ferroptosis-related genes (DE-m6A-Ferr-RGs) were obtained using differential expression analysis and Pearson correlation analysis.
Meiling Jiang, Weidong Zhao, Liyong Wu, Guofu Zhu   +3 more
openaire   +3 more sources