Results 141 to 150 of about 45,444 (316)

Exploring the Relevance of Disulfidptosis to the Pathophysiology of Ulcerative Colitis by Bioinformatics Analysis

Journal of Inflammation Research
Zhe Xiong,1,2 Ying Fang,1,2 Shuangshuang Lu,1 Qiuyue Sun,1,3 Yuhui Sun,1,3 Pengcheng Yang,4,* Jin Huang1,* 1Department of Gastroenterology, The Affiliated Changzhou No.2 People’s Hospital of Nanjing Medical University, Changzhou, Jiangsu Province,
Xiong Z, Fang Y, Lu S, Sun Q, Sun Y, Yang P, Huang J   +6 more
doaj  

Enhancing postmenopausal osteoporosis: a study of KLF2 transcription factor secretion and PI3K-Akt signaling pathway activation by PIK3CA in bone marrow mesenchymal stem cells

Archives of Medical Science
Introduction Mesenchymal stem cells can develop into osteoblasts, making them a promising cell-based osteoporosis treatment. Despite their therapeutic potential, their molecular processes are little known.
Wenjie Ma, Chen Li
doaj   +1 more source

Comparison of Clustering Methods for Time Course Genomic Data: Applications to Aging Effects

, 2014
Time course microarray data provide insight about dynamic biological processes. While several clustering methods have been proposed for the analysis of these data structures, comparison and selection of appropriate clustering methods are seldom discussed.
Horvath, Steve, Ophoff, Roel, Telesca, Donatello, Zhang, Yafeng   +3 more
core  

Identification of key proteins in early-onset Alzheimer’s disease based on WGCNA

Frontiers in Aging Neuroscience
IntroductionEarly-onset Alzheimer’s disease (EOAD) is sporadic, highly heterogeneous, and its underlying pathogenic mechanisms remain largely elusive. Proteomics research aims to uncover the biological processes and key proteins involved in disease progression.
Dazhi Li, Yaxin Wang, Jinliang Wang, Qiqiang Tang   +3 more
openaire   +3 more sources

Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses

Allergy, EarlyView.
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong, Kati Palosuo, Victoria Hinkkanen, Vittorio Fortino, Mika J. Mäkelä, Piia Karisola   +5 more
wiley   +1 more source

Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis. [PDF]

, 2019
The development of the mammalian retina is a complicated process involving the generation of distinct types of neurons from retinal progenitor cells (RPCs) in a spatiotemporal-specific manner.
An, Qin, Fan, Guoping, Hu, Youjin, Liu, Qinghuai, Mao, Xiying, Wang, Jinmei, Xi, Huiyu, Yang, Xian-Jie, Yuan, Songtao, Zhang, Xiangmei   +9 more
core  

Comprehensive Molecular Analyses of a Macrophage-Related Gene Signature With Regard to Prognosis, Immune Features, and Biomarkers for Immunotherapy in Hepatocellular Carcinoma Based on WGCNA and the LASSO Algorithm

, 2022
Tao Wang, Liqun Dai, Shu Shen, Yi Yang, Ming Yang, Xianwei Yang, Yiwen Qiu, Wentao Wang   +7 more
openalex   +1 more source

Glycosylation‐Related Genes Predict the Prognosis and Immune Fraction of Ovarian Cancer Patients Based on Weighted Gene Coexpression Network Analysis (WGCNA) and Machine Learning [PDF]

, 2022
Chen Zhao, Kewei Xiong, Fangrui Zhao, Abdalla Adam, Xiangpan Li   +4 more
openalex   +1 more source

Optic nerve sheath meningioma exhibits neural niche‐associated transcriptomic features and rare copy number variation‐linked evolution

Brain Pathology, EarlyView.
Optic nerve sheath meningiomas are typically NF2‐intact with few copy number alterations and are generally clinically indolent. Rare aggressive recurrences are associated with progressive accumulation of copy number variations, including CDKN2A/B homozygous deletion, 1q gain, and 14q loss.
Daisuke Sato, Satoru Miyawaki, Yu Sakai, Kenta Ohara, Yu Teranishi, Yudai Hirano, Motoyuki Umekawa, Takahiro Tsuchiya, Shotaro Ogawa, So Hirata, Hiroki Hongo, Hideaki Ono, Daisuke Komura, Tetsuo Ushiku, Shumpei Ishikawa, Nobuhito Saito   +15 more
wiley   +1 more source

Additional file 10 of Single-cell and WGCNA uncover a prognostic model and potential oncogenes in colorectal cancer

, 2022
Ziyang Di, Sicheng Zhou, Gaoran Xu, Lian Ren, Chengxin Li, Zheyu Ding, Kaixin Huang, Leilei Liang, Yihang Yuan   +8 more
openalex   +1 more source