Results 161 to 170 of about 45,444 (316)

Identification of prognostic biomarkers in neuroblastoma using WGCNA and multi-omics analysis

Discover Oncology
Neuroblastoma (NB) is one of the most frequent parenchymal tumors among children, with a high degree of heterogeneity and wide variation in clinical presentation. Despite significant therapeutic advances in recent years, long-term survival in high-risk patients remains low, emphasizing the urgent need to find new biomarkers and construct reliable ...
Yuhan Ke, Wenliang Ge
openaire   +3 more sources

Multi‐omics analyses shed lights on the evolution and fruit development of Chinese raspberries (Rubus spp.)

Journal of Integrative Plant Biology, EarlyView.
High‐quality genomes of four wild raspberry species, analysis of their genetic relationships, identification of centromeres as markers for tracing their hybrid origins, exploration of fruit quality regulation, and discovery of a gene blocking anthocyanin transport and thus causing yellow fruits provides valuable resources for raspberry breeding ...
Ticao Zhang, Dengli Luo, Guodong Li, Huanchong Wang, Qiang Cao, Rengang Zhang, Yuran Li, Yingan Zhu, Chunhua Ma, Aaron Liston, Hang Sun, Qin Qiao   +11 more
wiley   +1 more source

Module Preservation Across Breast Cancer RNA-seq Data Using WGCNA

, 2017
Breast cancer is the most common cancer in US, 61,000 new cases are expected to be diagnoised in 2016. Even though a list of differentially expressed genes and frequently mutated genes have been identified, the differential co-expression network and the module preservation between normal breast tissue and early stage in breast carcinogenesis haven’t ...
openaire   +1 more source

Combined Transcriptomic and Metabolomic Analysis Reveals an Ethylene‐Activated Regulatory Model on Monoterpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus

Plant Biotechnology Journal, EarlyView.
ABSTRACT Catharanthus roseus contains nearly 200 bioactive monoterpenoid indole alkaloids (MIAs) that are effective in treating cancer and other diseases. Ethylene plays a significant role in enhancing MIA biosynthesis, and we have found that it greatly induces the accumulation of anhydrovinblastine.
Bofu Deng, Qing Miao, Chaoqin Ou, Yuanbing Pan, Hang Liu, Xueqing Fu, Ling Li, Yuliang Wang, Kexuan Tang, Qifang Pan   +9 more
wiley   +1 more source

Identification and immunoinfiltration analysis of key genes in ulcerative colitis using WGCNA

PeerJ
Objective Ulcerative colitis (UC) is a chronic non-specific inflammatory bowel disease characterized by an unclear pathogenesis. This study aims to screen out key genes related to UC pathogenesis. Methods Bioinformatics analysis was conducted for screening key genes ...
Siyi Ni, Yingchao Liu, Jihong Zhong, Yan Shen   +3 more
openaire   +3 more sources

Metabolo‐Transcriptomics Analyses Reveal Alfalfa Adaptation to Combined Saline‐Alkali and Low‐Temperature Stress in the Field

Plant Biotechnology Journal, EarlyView.
ABSTRACT Alfalfa (Medicago sativa L.) is known as the ‘King of Forage’ because of its high protein content and excellent palatability. Alfalfa productivity is adversely affected in cold regions with saline‐alkali soils. However, the mechanisms underlying the response of alfalfa to combined saline‐alkali and low‐temperature stress under field conditions
Rui Guo, Lei Liu, Jiaqi Li, Hongyu Qu, Weileng Guo, Lishuang Zhang, Dihe Yang, Ruixin Wang, Changhong Guo   +8 more
wiley   +1 more source

Peer Review #2 of "Identifying DUSP-1 and FOSB as hub genes in immunoglobulin A nephropathy by WGCNA and DEG screening and validation (v0.1)"

, 2022
L Wang
openalex   +1 more source

Identification of a 5-Gene-Based Scoring System by WGCNA and LASSO to Predict Prognosis for Rectal Cancer Patients [PDF]

, 2021
He Huang, Shilei Xu, Aidong Chen, Fen Li, Jiezhong Wu, Xusheng Tu, Kunpeng Hu   +6 more
openalex   +1 more source

The Diversity of the DNA‐Binding Landscape in the DREB/ERF Family: Focusing on Reproductive Processes in Fruit Trees With Highly Heterozygous Genome

Plant Biotechnology Journal, EarlyView.
ABSTRACT DREB/ERF transcription factors play pivotal roles in plant development; however, their structural characteristics, DNA‐binding preferences, and functional roles in highly heterozygous woody plants remain insufficiently understood. Using lychee (Litchi chinensis) as a model, we identified 95 DREB/ERF genes subdivided into ten phylogenetic ...
Fengqi Wu, Jiakun Zheng, Huimin Hu, Hongsen Liu, Yaxuan Xiao, Junting Feng, Yanwei Hao, Chengjie Chen, Rui Xia, Zaohai Zeng   +9 more
wiley   +1 more source

VvERF045 Integrates Ethylene, Brassinosteroid and Abscisic Acid Pathways to Orchestrate Anthocyanin Biosynthesis in Grapevine

Plant Biotechnology Journal, EarlyView.
ABSTRACT Anthocyanin biosynthesis in non‐climacteric grape berries is regulated through coordinated phytohormonal signalling networks. However, the precise mechanisms by which abscisic acid (ABA), brassinosteroids (BRs) and ethylene (ET) synergistically modulate this process remain unclear.
Jiajia Li, Qifei Gao, Yi Quan, Ruo he Yin, Boyang Liu, Yang Hu, Song tao Jiu, Bin Han, Ying Zhang, Jiayu Han, Shuli Han, Dinghan Guo, Chao Ma, Caixi Zhang, Lei Wang, Shiping Wang   +15 more
wiley   +1 more source