Results 41 to 50 of about 62,645 (251)
Mechanisms of leptin secretion from white adipocytes [PDF]
American Journal of Physiology-Cell Physiology, 2002 The mechanisms regulating leptin secretion were investigated in isolated rat white adipocytes. Insulin (1–100 nM) linearly stimulated leptin secretion from incubated adipocytes for at least 2 h. The adrenergic agonists norepinephrine, isoproterenol (two nonselective β-agonists), or CL-316243 (potent β3) all inhibited insulin (10 nM)-stimulated leptin ...
Philippe G, Cammisotto +1 more
openaire +2 more sources
Integrin αV Mediates the Effects of Irisin on Human Mature Adipocytes
Obesity Facts, 2022 Introdution and Aims: The myokine irisin is critical to modulating adipocytes thermogenesis and influence whole-body metabolism. However, whether there is difference in the effects of irisin on adipocytes derived from different depots remains unknown ...
Tingting Fu +6 more
doaj +1 more source
Differentiation of human adipose-derived stem cells into brite (brown-in-white) adipocytes
Frontiers in Endocrinology, 2011 It is well established now that adult humans possess active brown adipose tissue which represents a potential pharmacological target to combat obesity and associated diseases.
Didier F Pisani +6 more
doaj +1 more source
Journal of Obesity, 2015 Physical exercise accelerates the mobilization of free fatty acids from white adipocytes to provide fuel for energy. This happens in several tissues and helps to regulate a whole-body state of metabolism.
Junetsu Ogasawara +8 more
doaj +1 more source
ESRRG and PERM1 Govern Mitochondrial Conversion in Brite/Beige Adipocyte Formation
Frontiers in Endocrinology, 2020 When exposed to cold temperatures, mice increase their thermogenic capacity by an expansion of brown adipose tissue mass and the formation of brite/beige adipocytes in white adipose tissue depots.
Sebastian Müller +8 more
doaj +1 more source
Frontiers in Physiology, 2021 The mammalian target of rapamycin (mTOR) is an important protein kinase that senses changes in extracellular and intracellular energy levels and plays a key role in regulating energy metabolism.
Bahetiyaer Huwatibieke +10 more
doaj +1 more source
Src family kinases suppress differentiation of brown adipocytes and browning of white adipocytes [PDF]
Genes to Cells, 2016 Brown adipocytes and beige adipocytes can expend energy, generate heat, and increase whole‐body energy expenditure. The detailed mechanisms of adipogenesis and thermogenesis of these cells are still obscure. Here, we show that Src family kinases (SFKs) regulate both brown adipogenesis and browning of white adipocytes.
Mai, Usui +2 more
openaire +2 more sources
Deciphering White Adipose Tissue Heterogeneity
Biology, 2019 Adipose tissue not only stores energy, but also controls metabolism through secretion of hormones, cytokines, proteins, and microRNAs that affect the function of cells and tissues throughout the body.
Quyen Luong, Jun Huang, Kevin Y. Lee
doaj +1 more source
White adipocytes are less prone to apoptotic stimuli than brown adipocytes in rodent [PDF]
Cell Death & Differentiation, 2006 n ...
E. Nisoli +9 more
openaire +5 more sources
HOXC10 suppresses browning to maintain white adipocyte identity
Diabetes, 2021 Promoting beige adipocyte development within white adipose tissue (WAT) is a potential therapeutic approach to staunch the current obesity epidemic. Previously, we identified homeobox-containing transcription factor HOXC10 as a suppressor of browning in subcutaneous WAT.
H.Y. Angeline Tan +9 more
openaire +4 more sources