Results 21 to 30 of about 62,645 (251)

Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition

open access: yesBiology of Sex Differences, 2022
Highlights 1. Androgen excess in PCOS model is associated with decreased markers of mitochondrial content in both subcutaneous and visceral white adipose tissue. 2.
Jacob E. Pruett   +9 more
doaj   +1 more source

Adrenoceptors in white, brown, and brite adipocytes [PDF]

open access: yesBritish Journal of Pharmacology, 2019
Adrenoceptors play an important role in adipose tissue biology and physiology that includes regulating the synthesis and storage of triglycerides (lipogenesis), the breakdown of stored triglycerides (lipolysis), thermogenesis (heat production), glucose metabolism, and the secretion of adipocyte‐derived hormones that can control whole‐body energy ...
Bronwyn A. Evans   +3 more
openaire   +2 more sources

Adipocytes and Stromal Cells Regulate Brown Adipogenesis Through Secretory Factors During the Postnatal White-to-Brown Conversion of Adipose Tissue in Syrian Hamsters

open access: yesFrontiers in Cell and Developmental Biology, 2021
Brown adipose tissue (BAT) is a specialized tissue that regulates non-shivering thermogenesis. In Syrian hamsters, interscapular adipose tissue is composed primarily of white adipocytes at birth, which is converted to BAT through the proliferation and ...
Junnosuke Mae   +6 more
doaj   +1 more source

Enhancement of the Antiobesity and Antioxidant Effect of Purple Sweet Potato Extracts and Enhancement of the Effects by Fermentation

open access: yesAntioxidants, 2021
The browning of white adipocytes, which transforms energy-storing white adipocytes to heat-producing beige adipocytes, is considered a strategy against metabolic diseases.
Seul Gi Lee   +6 more
doaj   +1 more source

Artepillin C, a Typical Brazilian Propolis-Derived Component, Induces Brown-Like Adipocyte Formation in C3H10T1/2 Cells, Primary Inguinal White Adipose Tissue-Derived Adipocytes, and Mice. [PDF]

open access: yesPLoS ONE, 2016
Induction of brown-like adipocytes (beige/brite cells) in white adipose tissue (WAT) suggests a new approach for preventing and treating obesity via induction of thermogenesis associated with uncoupling protein 1 (UCP1).
Sho Nishikawa   +9 more
doaj   +1 more source

Regulatory mechanism of white adipocyte browning and research advances [PDF]

open access: yesBIO Web of Conferences
Adipose tissue has energy storage and metabolic functions, and its content is highly correlated with an individual’s obesity status. The relative proportions of white adipocytes, brown adipocytes, and beige adipocytes are also important in regulating ...
Wang Zihan
doaj   +1 more source

Heparan Sulfate: A Regulator of White Adipocyte Differentiation and of Vascular/Adipocyte Interactions

open access: yesBiomedicines, 2022
White adipose tissues are major endocrine organs that release factors, termed adipokines, which affect other major organ systems. The development and functions of adipose tissues depend largely upon the glycosaminoglycan heparan sulfate. Heparan sulfate proteoglycans (HSPGs) surround both adipocytes and vascular structures and facilitate the ...
J. Michael Sorrell, Arnold I. Caplan
openaire   +3 more sources

Heritability of fat accumulation in white adipocytes

open access: yesAmerican Journal of Physiology-Endocrinology and Metabolism, 2014
Since individual cells from freshly isolated white adipose tissue (WAT) exhibit variable levels of fat accumulation, we attempted to determine which factor(s) cause this variation. We used primary WAT cells from adult mice and the mouse 3T3-L1 cell-line of preadipocytes for these studies.
Liora S, Katz   +2 more
openaire   +3 more sources

A Method to Induce Brown/Beige Adipocyte Differentiation from Murine Preadipocytes

open access: yesBio-Protocol, 2021
Adipocytes exhibit different morphological and functional characteristics, depending on their anatomical location, developmental origin, and stimulus. While white adipocytes tend to accumulate energy as triglycerides, brown and beige adipocytes tend to ...
Andréa Rocha   +3 more
doaj   +1 more source

Intrinsic Properties of Brown and White Adipocytes Have Differential Effects on Macrophage Inflammatory Responses

open access: yesMediators of Inflammation, 2017
Obesity is marked by chronic, low-grade inflammation. Here, we examined whether intrinsic differences between white and brown adipocytes influence the inflammatory status of macrophages.
Louisa Dowal   +13 more
doaj   +1 more source

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