Ceiling culture of human mature white adipocytes with a browning agent: A novel approach to induce transdifferentiation into beige adipocytes [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Excess and dysfunctional adipose tissue plays an important role in metabolic diseases, including obesity, atherosclerosis and type 2 diabetes mellitus. In mammals, adipose tissue is categorized into two types: white and brown.
Yufei He +6 more
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IL-27 increases energy storage in white adipocytes by enhancing glucose uptake and fatty acid esterification [PDF]
Adipocyte, 2023 The cytokine interleukin (IL)-27 has been reported to induce thermogenesis in white adipocytes. However, it remains unknown whether IL-27-mediated adipocyte energy dissipation is paralleled by an elevated energy supply from lipids and/or carbohydrates ...
Chiara Scaffidi +3 more
doaj +2 more sources
Analysis of the different characteristics between omental preadipocytes and differentiated white adipocytes using bioinformatics methods [PDF]
Adipocyte, 2022 Obesity is emerging as an epidemiological issue, being associated with the onset and progress of various metabolism-related disorders. Obesity is characterized by the white adipose expansion, which encounters white adipocyte hypertrophy and hyperplasia ...
Xinyu Yang +5 more
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Distinct signalling dynamics of BMP4 and BMP9 in brown versus white adipocytes [PDF]
Scientific ReportsAdipocyte dysfunction contributes to lipotoxicity and cardiometabolic diseases. Bone morphogenetic protein 4 (BMP4) is expressed in white adipocytes and remodels white adipose tissue, while liver-derived BMP9, a key circulating BMP, influences adipocyte ...
Benjamin Constant +9 more
doaj +2 more sources
AMP-Activated Kinase (AMPK) Activation by AICAR in Human White Adipocytes Derived from Pericardial White Adipose Tissue Stem Cells Induces a Partial Beige-Like Phenotype. [PDF]
PLoS ONE, 2016 Beige adipocytes are special cells situated in the white adipose tissue. Beige adipocytes, lacking thermogenic cues, morphologically look quite similar to regular white adipocytes, but with a markedly different response to adrenalin.
Omar Abdul-Rahman +18 more
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Cell Reports, 2019 Summary: White adipose tissue (WAT) is a central factor in the development of type 2 diabetes, but there is a paucity of translational models to study mature adipocytes.
Matthew J. Harms +12 more
doaj +3 more sources
Peritumoral adipose tissue promotes lipolysis and white adipocytes browning by paracrine action [PDF]
Frontiers in Endocrinology, 2023 BackgroundStromal adipocytes and tumor breast epithelial cells undergo a mutual metabolic adaptation within tumor microenvironment. Therefore, browning and lipolysis occur in cancer associated adipocytes (CAA).
Priscila Pagnotta +13 more
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Elevated UCP1 levels are sufficient to improve glucose uptake in human white adipocytes
Redox Biology, 2019 Brown adipose tissue (BAT) has been considered beneficial for metabolic health by participating in the regulation of glucose homoeostasis. The browning factors that improve glucose uptake beyond normal levels are still unknown but glucose uptake is not ...
D. Tews +7 more
doaj +3 more sources
PLoS Biology, 2019 Lipid species patterns are conserved within cells to maintain physicochemical properties of membranes and cellular functions. We present the lipidome, including sterols, glycerolipids (GLs), glycerophospholipids (GPLs), and sphingolipids (SLs), of ...
Sabine Schweizer +7 more
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Identification of Biochemical Differences in White and Brown Adipocytes Using FTIR Spectroscopy
Applied Sciences, 2022 This study was conducted to investigate the developmental characteristics of adipocytes and to identify selectively white and brown adipocytes through Fourier transform infrared (FTIR) spectroscopy.
DongHyun Shon +3 more
doaj +1 more source